A5002414265- Silk-based biomaterials and applications
- Neuroscience and Neural Engineering
- Advanced Memory and Neural Computing
- Conducting polymers and applications
- EEG and Brain-Computer Interfaces
- Advanced Sensor and Energy Harvesting Materials
- Biochemical and Structural Characterization
- Photoreceptor and optogenetics research
- Nanofabrication and Lithography Techniques
- Neurobiology and Insect Physiology Research
- Terahertz technology and applications
- Advanced Materials and Mechanics
- Neural dynamics and brain function
- Polydiacetylene-based materials and applications
- Advanced Chemical Sensor Technologies
- Photonic and Optical Devices
- Metamaterials and Metasurfaces Applications
- 3D Printing in Biomedical Research
- Analytical Chemistry and Sensors
- Silkworms and Sericulture Research
- Millimeter-Wave Propagation and Modeling
- Electrospun Nanofibers in Biomedical Applications
- Plasmonic and Surface Plasmon Research
- Neurological disorders and treatments
- Nerve injury and regeneration
State Key Laboratory of Transducer Technology
2016-2025
Shanghai Institute of Microsystem and Information Technology
2016-2025
Chinese Academy of Sciences
2016-2025
University of Chinese Academy of Sciences
2017-2025
Aerospace Information Research Institute
2025
Southern Medical University
2023-2024
Shanghai University
2024
Shanghai University of Sport
2024
People's Hospital of Xinjiang Uygur Autonomous Region
2015
A set of biocompatible, biodegradable, and biofunctionalizable diffractive optical elements (DOEs) using silk proteins as the building materials is reported. The diffraction pattern a DOE highly sensitive to surrounding environment structural integrity, offering numerous opportunities for biosensing applications.
Abstract Self‐powered electronics using triboelectric nanogenerators (TENGs) is drawing increasing efforts and rapid advancements in eco/biocompatible energy harvesting, intelligent sensing, biomedical applications. Currently, the performances are mainly determined by pair materials’ inherent electron affinity difference, merely tuned chemical or physical methods, which significantly limit optional variety output capability, especially for natural‐biomaterial‐based TENGs. Herein, a...
Mechanical signals such as pressure and strain reflect important psychological physiological states of the human body. Body-integrated sensors, including skin-mounted surgically implanted ones, allow personalized health monitoring for general population well patients. However, development measuring devices has been hindered by strict requirements human-biocompatible materials need high performance sensors; most existing or sensors do not meet all desired specifications. Here, a set flexible,...
Abstract Silk protein fibres produced by silkworms and spiders are renowned for their unparalleled mechanical strength extensibility arising from high-β-sheet crystal contents as natural materials. Investigation of β-sheet-oriented conformational transitions in silk proteins at the nanoscale remains a challenge using conventional imaging techniques given limitations chemical sensitivity or limited spatial resolution. Here, we report on electron-regulated polymorphic revealed near-field...
The combination of optogenetics and electrophysiological recording enables high-precision bidirectional interactions between neural interfaces circuits, which provides a promising approach for the study progressive neurophysiological phenomena. Opto-electrophysiological probes with sufficient flexibility biocompatibility are desirable to match low mechanical stiffness brain tissue chronic reliable performance. However, lack rigidity poses challenges accurate implantation flexible less...
Abstract Recent progress in ultrafast spectroscopy and semiconductor technology is enabling unique applications screening, detection, diagnostics the Terahertz (T‐ray) regime. The promise of efficaciously operation this spectral region tempered by lack devices that can spectrally analyze samples at sufficient temporal spatial resolution. Real‐time, multispectral T‐ray (Mul‐T) imaging reported designing demonstrating hyperspectral metamaterial focal plane array (MM‐FPA) interfaces allowing...
Abstract Controllable degradation and excellent biocompatibility during/after a lifetime endow emerging transient electronics with special superiority in implantable biomedical applications. Currently, most of these devices need external power sources, limiting their real‐world utilizations. Optimizing existing bioresorbable electronic requires natural‐material‐based construction and, more importantly, diverse or even all‐in‐one multifunctionalization. Herein, silk‐based implantable,...
Abstract Flexible electronics can serve as powerful tools for biomedical diagnosis and therapies of neurological disorders, particularly application cases with brain–machine interfaces (BMIs). Existing conformal soft bioelectrodes are applicable basic electrocorticogram (ECoG) collecting/monitoring. Nevertheless, an emerging promising approach, further multidisciplinary efforts still demanded in‐depth exploitations these toward their practical neurophysiological applications in both...
Advancements in microscale electrode technology have revolutionized the field of neuroscience and clinical applications by offering high temporal spatial resolution recording stimulation. Flexible neural probes, with their mechanical compliance to brain tissue, been shown be superior rigid devices terms stability longevity chronic recordings. Shuttle are commonly used assist flexible probe implantation; however, protective membrane still makes penetration difficult. Hidden damage vessels...
Abstract Precise patterning of polymer‐based biomaterials for functional bio‐nanostructures has extensive applications including biosensing, tissue engineering, and regenerative medicine. Remarkable progress is made in both top‐down (based on lithographic methods) bottom‐up (via self‐assembly) approaches with natural synthetic biopolymers. However, most methods only yield 2D pseudo‐3D structures restricted geometries functionalities. Here, it reported that precise nanostructuring genetically...
Precise patterning of biomaterials has widespread applications, including drug release, degradable implants, tissue engineering, and regenerative medicine. Patterning protein‐based microstructures using UV‐photolithography been demonstrated protein as the resist material. The Achilles heel existing biophotoresists is inevitable wide molecular weight distribution during extraction/regeneration process, hindering their practical uses in semiconductor industry where reliability repeatability...
Abstract Implantable bioelectronic devices, designed for both monitoring and modulating living organisms, require functional biological adaptability. Pure silk is innovatively employed, which known its excellent biocompatibility, to engineer water‐triggered, geometrically reconfigurable membranes, on functions can be integrated by Micro Electro Mechanical System (MEMS) techniques specially functionalized silk. These devices undergo programmed shape deformations within 10 min once triggered...
Ultraflexible neural electrodes have shown superior stability compared with rigid in long-term vivo recordings, owing to their low mechanical mismatch brain tissue. It is desirable detect neurotransmitters as well electrophysiological signals for months science. This work proposes a stable electronic interface that can simultaneously electrical activity and dopamine concentration deep the brain. ultraflexible electrode modified by nanocomposite of reduced graphene oxide (rGO)...
Abstract Metamaterial (MM) sensors and devices, usually consisting of artificially structured composite materials with engineered responses that are mainly determined by the unit structure rather than bulk properties or composition, offer new functionalities not readily available in nature. A set implantable resorbable therapeutic MM devices at terahertz (THz) frequencies designed fabricated patterning magnesium split ring resonators on drug‐loaded silk protein substrates controllable device...
Global atmospheric CO2 concentrations, driven by anthropogenic emissions and natural carbon cycle dynamics, have emerged as a critical accelerator of climate change. However, due to the spatiotemporal heterogeneity sources sinks, estimating flux remains highly uncertain. Accurately quantifying contribution various sinks concentration is essential for understanding global balance. In this study, GEOS-Chem (version 13.2.1), MERRA-2 meteorological data, was used simulate monthly concentrations...