A5089344475- Advanced Graph Theory Research
- Complexity and Algorithms in Graphs
- Optimization and Search Problems
- Algorithms and Data Compression
- Scheduling and Optimization Algorithms
- Genome Rearrangement Algorithms
- Gene expression and cancer classification
- RNA and protein synthesis mechanisms
- Optimization and Packing Problems
- Genomics and Phylogenetic Studies
- Advanced Manufacturing and Logistics Optimization
- VLSI and FPGA Design Techniques
- graph theory and CDMA systems
- Protein Structure and Dynamics
- Machine Learning in Bioinformatics
- Interconnection Networks and Systems
- DNA and Biological Computing
- Graph Labeling and Dimension Problems
- Bioinformatics and Genomic Networks
- Computational Geometry and Mesh Generation
- Genetic Mapping and Diversity in Plants and Animals
- Assembly Line Balancing Optimization
- Metabolomics and Mass Spectrometry Studies
- Constraint Satisfaction and Optimization
- Limits and Structures in Graph Theory
University of Alberta
2015-2024
Gansu Provincial Maternal and Child Health Hospital
2024
Virginia Commonwealth University
2024
Shenzhen Bao'an District People's Hospital
2020-2022
Wuhan University of Technology
2022
ZTE (United States)
2022
Guangdong Medical College
2019
Guangdong Provincial People's Hospital
2018
Zhejiang Sci-Tech University
2015-2017
Athabasca University
2012-2014
Arc-annotated sequences are useful in representing the structural information of RNA sequences. In general, secondary and tertiary structures can be represented as a set nested arcs crossing arcs, respectively. Since functions largely determined by molecular confirmation therefore structures, comparison between has received much attention recently. this paper, we propose notion edit distance to measure similarity two incorporating various operations performed on both bases (i.e.,...
Identification of unknown metabolites is a major challenge in metabolomics. Without the identities metabolites, metabolome data generated from biological sample cannot be readily linked with proteomic and genomic information for studies systems biology medicine. We have developed web-based metabolite identification tool (http://www.mycompoundid.org) that allows searching interpreting mass spectrometry (MS) against newly constructed library composed 8 021 known human endogenous their...
Abstract Background Microarray data analysis is notorious for involving a huge number of genes compared to relatively small samples. Gene selection detect the most significantly differentially expressed under different conditions, and it has been central research focus. In general, better gene method can improve performance classification significantly. One difficulties in that numbers samples conditions vary lot. Results Two novel methods are proposed this paper, which not affected by...
High-performance chemical isotope labeling (CIL) liquid chromatography-mass spectrometry (LC-MS) is an enabling technology based on rational design of reagents to target a class metabolites sharing the same functional group (e.g., all amine-containing or amine submetabolome) provide concomitant improvements in metabolite separation, detection, and quantification. However, identification labeled remains be analytical challenge. In this work, we describe library standards search method for CIL...
We report an analytical tool to facilitate metabolite identification based on MS/MS spectral match of unknown a library predicted spectra possible human metabolites. To construct the library, known endogenous metabolites in Human Metabolome Database (HMDB) (8,021 metabolites) and their metabolic products via one reaction Evidence-based Library (EML) (375,809 were subjected silico fragmentation produce spectra. This is hosted at public MCID Web site (www.MyCompoundID.org), search program,...
The recently constructed river buffalo whole-genome radiation hybrid panel (BBURH5000) has already been used to generate preliminary (RH) maps for several chromosomes, and buffalo-bovine comparative chromosome have constructed. Here, we present the first-generation whole genome RH map (WG-RH) of generated from cattle-derived markers. aligned bovine sequence assembly Btau_4.0, providing valuable mapping information both species. A total 3990 markers were typed on BBURH5000 panel, which 3072...
PROSESS (PROtein Structure Evaluation Suite and Server) is a web server designed to evaluate validate protein structures generated by X-ray crystallography, NMR spectroscopy or computational modeling. While many structure evaluation packages have been developed over the past 20 years, unique in its comprehensiveness, capacity X-ray, predicted as well ability variety of experimental data. integrates previously developed, well-known thoroughly tested methods both global residue specific: (i)...
Abstract ChatGPT has surprised academia with its remarkable abilities but also raised substantial concerns regarding academic integrity and misconduct. Despite the debate, empirical research exploring issue is limited. The purpose of this study to bridge gap by analyzing Twitter data understand how perceiving ChatGPT. A total 9733 tweets were collected through Python via API in three consecutive weeks May June 2023; 3000 most relevant ones analyzed Atlas ti. 23. Our findings reveal a...
Microarray gene expression data often contains multiple missing values due to various reasons. However, most of analysis algorithms require complete data. Therefore, accurate estimation the is critical further analysis. In this paper, an Iterated Local Least Squares Imputation (ILLSimpute) method proposed for estimating values. Two unique features ILLSimpute are: does not fix a common number coherent genes target purpose, but defines as those within distance threshold genes. Secondly, in...
Given a set of species and their similarity data, an important problem in evolutionary biology is how to reconstruct phylogeny (also called tree) so that are close the if only they have high similarity. Assume data represented as graph G = (V, E), where each vertex represents two vertices adjacent represent The reconstruction can then be abstracted finding (phylogenetic) tree T from given such (1) has no degree-2 internal nodes, (2) external nodes (i.e., leaves) exactly elements V, (3) $(u,...
Abstract Suffering an acute spinal cord injury (SCI) can result in catastrophic physical and emotional loss. Efforts to translate novel therapies clinical trials are impeded by the SCI community’s singular dependence upon functional outcome measures. Therefore, a compelling rationale exists establish neurochemical biomarkers for objective classification of severity. In this study, CSF serum samples were obtained at 3 time points (~24, 48, 72 hours post-injury) from 30 patients (10 AIS A, 12...
In order to mitigate the effects of a changing climate, agriculture requires more effective evaluation, selection, and production crop cultivars in accelerate genotype-to-phenotype connections selection beneficial traits. Critically, plant growth development are highly dependent on sunlight, with light energy providing plants required photosynthesize as well means directly intersect environment develop. analyses, machine learning deep techniques have proven ability learn patterns, including...
Given a digraph G=(V,E), the k-path partition problem aims to find minimum collection of vertex-disjoint directed paths, each order at most k, cover all vertices V. The has various applications in facility location, network monitoring, transportation networks and others. Its special case on undirected graphs is NP-hard when k≥3, received much study recently from approximation algorithm perspective. However, general digraphs seemingly untouched literature. We fill gap with first...