- Asthma and respiratory diseases
- Cystic Fibrosis Research Advances
- Neonatal Respiratory Health Research
- Liver Disease Diagnosis and Treatment
- Respiratory viral infections research
- Hepatocellular Carcinoma Treatment and Prognosis
- Tracheal and airway disorders
- Allergic Rhinitis and Sensitization
- Respiratory and Cough-Related Research
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Respiratory Support and Mechanisms
- Inflammatory Bowel Disease
- Pediatric health and respiratory diseases
- COVID-19 Clinical Research Studies
- Microscopic Colitis
- Inhalation and Respiratory Drug Delivery
- Hepatitis C virus research
- Liver Disease and Transplantation
- Long-Term Effects of COVID-19
- Urticaria and Related Conditions
- Congenital Diaphragmatic Hernia Studies
- Eosinophilic Esophagitis
- Colorectal Cancer Treatments and Studies
- Food Allergy and Anaphylaxis Research
- Olfactory and Sensory Function Studies
University of Catania
2016-2025
Misericordia University
2024
Azienda Unità Sanitaria Locale di Ferrara
2024
Agostino Gemelli University Polyclinic
2024
Istituto Ortopedico Gaetano Pini
2022
Policlinico Universitario di Catania
2008-2022
University of Messina
2022
ORCID
2021
Sapienza University of Rome
2020-2021
Brescia University
2020-2021
To date cytokines profile in AEDS is poorly described children. We evaluated the interleukin (IL)-17, IL-23, and IL-10 levels atopic eczema/dermatitis syndrome (AEDS) children healthy controls, (aAEDS) nonatopic (naAEDS) subtypes their relationship with disease severity. A total of 181 aAEDS 93 were evaluated. According to skin-prick test (SPT) for allergens serum IgE, all patients subdivided two groups: 104 77 naAEDS. In patients, IL-17, detected. Serum IL-17 IL-23 significantly higher,...
Cystic fibrosis transmembrane conductance regulator (CFTR) modulators represent targeted therapies directly acting on the CFTR channel. The triple therapy Elexacaftor/Tezacaftor/Ivacaftor (ELX/TEZ/IVA) has been demonstrated to improve lung function and quality of life in cystic (CF) patients. However, effects ELX/TEZ/IVA sleep-disordered breathing (SDB) respiratory muscle strength are poorly studied. aim this study was assess patients with CF severe disease cardiorespiratory polygraphy...
The COVID-19 pandemic has had a significant impact on the epidemiology of respiratory viruses. Non-pharmaceutical interventions (NPIs) led to dramatic reduction in infections. However, long-term effects virus remain unclear.We conducted comparative study hospitalized pediatric patients with illness during two seasons: 1 October 2021 15 March 2022 and 2023. We compared type virus, mean duration hospitalization, disease severity.In first season, 47.1% (65/138) tested positive for at least one...
Abstract The clinical spectrum of SARS‐CoV‐2 infection is mixed. It ranges from asymptomatic cases, medium‐intensity forms with mild to moderate symptoms, severe ones bilateral lung involvement and respiratory distress, which can require transfer ICUs intubation. In most the picture characterized by a persistent fever, cough, dyspnoea, expectoration, myalgias, arthralgias, headache, gastrointestinal nasal congestion, pharyngodynia. spread COVID‐19 in Europe has highlighted an atypical...
Recently, type 2 inflammation has been recognized as one of the most critical factors participating in pathogenesis cystic fibrosis (CF). On hand, restores tissue homeostasis and contributes to resolution following an injury. other response-activated immune cells may become dysregulated or chronically activated, causing fibrosis. Among cytokine-driven inflammatory pathways, transforming growth factor β (TGFβ), interleukin (IL)-17, IL-33, IL-13 have identified essential mediators patients...
Abstract Background Recurrent respiratory infections (RRIs) are defined by the presence of at least one following criteria: (i) > 6 annual (RIs); (ii) 1 monthly RIs involving upper airways from September to April; (iii) 3 lower represent a very common health problem in first years life. We conducted multi-centre, prospective, single-open study assess efficacy and safety Streptococcus salivarius 24SMBc oralis 89a prevention tract (URTIs) children. Methods Ninety-one children (M:F = 47:44,...