Zhijie Shi

ORCID: 0000-0003-4291-0910
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About
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Research Areas
  • MicroRNA in disease regulation
  • Circular RNAs in diseases
  • Estrogen and related hormone effects
  • Vitamin D Research Studies
  • Epigenetics and DNA Methylation
  • Colorectal Cancer Surgical Treatments
  • Cancer-related molecular mechanisms research
  • Cancer Genomics and Diagnostics
  • Breast Cancer Treatment Studies
  • Prostate Cancer Treatment and Research
  • Adipokines, Inflammation, and Metabolic Diseases
  • Regulation of Appetite and Obesity
  • Inflammasome and immune disorders
  • Folate and B Vitamins Research
  • Pancreatic and Hepatic Oncology Research
  • Advanced Breast Cancer Therapies
  • Acute Ischemic Stroke Management
  • Colorectal Cancer Screening and Detection

First Hospital of Shanxi Medical University
2025

Shanxi Medical University
2025

Zhejiang Shuren University
2021-2024

First Affiliated Hospital of Henan University of Science and Technology
2018-2022

Tangshan Gongren Hospital
2017-2018

The aim of this study was to perform a systematic review and meta-analysis evaluate the value Glasgow prognostic score (GPS) or modified (mGPS) in patients with colorectal cancer (CRC).A comprehensive medical literature search performed using online databases PubMed, Embase, Web Science, Cochrane Library. After extracting basic characteristics data from included studies, overall survival (OS) cancer-specific (CSS) were pooled as primary outcomes. Subgroup analyses according therapeutic...

10.2147/cmar.s185350 article EN cc-by-nc Cancer Management and Research 2018-12-01

Background Breast cancer is a significant public health issue, exhibiting the most pronounced occurrence and fatality rates among malignant neoplasms globally. Targeted therapy medical intervention that focuses on specific molecular markers. This study aims to investigate evaluate current research trends directions in field of targeted for breast using bibliometric analysis. Method The Web Science database was utilized retrieve relevant articles published between 2003 2022. VOSviewer...

10.3389/fonc.2024.1366900 article EN cc-by Frontiers in Oncology 2024-06-04

Minor ischemic strokes, despite their initial mild symptoms, pose a significant risk of recurrence, potentially leading to severe disability. The role C-reactive protein (CRP) gene variants in predicting the recurrent minor stroke, particularly interaction with lifestyle factors such as smoking, remains unclear. We aimed investigate relationship single-nucleotide polymorphisms (SNPs) CRP stroke focusing on gene-environment interactions. A retrospective cohort study was conducted using data...

10.1186/s40001-025-02355-3 article EN cc-by-nc-nd European journal of medical research 2025-03-18

Gastric cancer (GC) is one of the most common malignant tumors. Circular RNA (circRNA) has been shown to be involved in progression GC. However, function circ_0008035 GC not studied. Quantitative real-time polymerase chain reaction (qRT-PCR) was used detect expression circ_0008035, microRNA-1256 (miR-1256) and carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6). 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT) assay, 5-ethynyl-2'-deoxyuridine (EdU) flow...

10.1080/15384101.2022.2041354 article EN Cell Cycle 2022-02-28

Numerous previous studies reported the association of Vitamin D receptor gene Taq Ipolymorphism with prostate cancer risk, however these results were controversial. In order to provide a relatively comprehensive description this relationship, we conducted meta-analysis by searching PubMed, Embase, and China National Knowledge Infrastructure. Finally, 36 8,423 cases 8,887 controls included. I polymorphism was found marginally increase risk in recessive genetic model (tt/Tt vs. TT: Odds Ratio...

10.18632/oncotarget.23606 article EN Oncotarget 2017-12-22

This study focused on the investigation into how HMGB3 works in breast cancer (BC) progression. Firstly, we analyzed relationship between and BC patients through TCGA database. We performed qRT-PCR for determining mRNA level Western blot detecting protein of cell lines. CCK-8, flow cytometry, transwell, wound healing assays were utilized to detect effect phenotypes. Next, prediction binding site shared by miR-145-5p was bioinformatics method. The targeting validated using dual-luciferase...

10.1155/2022/1954099 article EN Computational and Mathematical Methods in Medicine 2022-11-10
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