A5050036587- Mycobacterium research and diagnosis
- Pharmacological Effects of Natural Compounds
- Tuberculosis Research and Epidemiology
- Immune responses and vaccinations
- Autoimmune and Inflammatory Disorders
- Immunodeficiency and Autoimmune Disorders
- Ginseng Biological Effects and Applications
- Gut microbiota and health
- Alzheimer's disease research and treatments
- Diabetes and associated disorders
- Cancer Mechanisms and Therapy
- Neuroinflammation and Neurodegeneration Mechanisms
- Parkinson's Disease Mechanisms and Treatments
- Cytomegalovirus and herpesvirus research
- Infectious Diseases and Mycology
- Immune Cell Function and Interaction
- Cytokine Signaling Pathways and Interactions
- Helicobacter pylori-related gastroenterology studies
- Salivary Gland Disorders and Functions
- Sarcoidosis and Beryllium Toxicity Research
- Infection Control in Healthcare
- Restless Legs Syndrome Research
- Telomeres, Telomerase, and Senescence
- Humic Substances and Bio-Organic Studies
- Medical Device Sterilization and Disinfection
Smith-Kettlewell Eye Research Institute
2014-2025
University of Wisconsin–Madison
2015-2025
Wisconsin Institutes for Discovery
2024-2025
Chippewa Valley Technical College
2006-2018
McPherson College
2015-2018
Temple University Health System
2017
Charleston Area Medical Center
2015
Highland Community College - Illinois
2006-2008
Bronson Methodist Hospital
1976
On March 24 and 25, 2017 researchers clinicians from around the world met at Temple University in Philadelphia to discuss current knowledge of Mycobacterium avium ssp. Paratuberculosis (MAP) its relationship human disease. The conference was held because shared concern that MAP is a zoonotic bacterium poses threat not only animal health but also health. In order further study this problem, conferees discussed ways improve diagnostic tests potential future anti-MAP clinical trials....
Telomere attrition and corresponding cellular senescence of the retinal pigment epithelium contribute to changes age-related macular degeneration. Activation enzyme telomerase can add telomeric DNA chromosomal ends has been proposed as a treatment for We report use small molecule, oral activator (TA)-65 in early This study, focusing on degeneration, provides model TAs disease.Thirty-eight (38) patients were randomly assigned 1-year, double-blinded, placebo-controlled interventional study...
Background and Aim of the Work. Blau syndrome is an inherited granulomatous inflammatory disorder with clinical findings uveitis, arthritis, dermatitis. Although rare, shares features more common diseases sarcoidosis Crohn's disease. The are indistinguishable from juvenile sarcoidosis; mutations on same gene chromosome 16 (CARD15) that confers susceptibility to product this part innate immune system. Mycobacterium avium ss. paratuberculosis (MAP) putative cause disease has been implicated as...
Mycobacterium avium subspecies paratuberculosis (MAP) is the known infectious cause of Johne’s disease, an enteric inflammatory disease mostly studied in ruminant animals. MAP has also been implicated very similar Crohn’s humans as well sarcoidosis. Recently, associated with juvenile sarcoidosis (Blau syndrome), autoimmune diabetes, thyroiditis, and multiple sclerosis. While it intuitive to implicate granulomatous diseases where microbe participates granuloma, more difficult assign a role...
Kuenstner JT conceived of the combined UVBI and antibiotic treatment protocol discovered MAP infections in all cases; Chamberlin W Telega G were treating physicians for patient 1 W, Weg S John K 2; Naser SA, Collins MT Aitken JM performed cultures serologic assays on patients through 5; Eckstein TM a assay leprosy 2 provided guidance presentation case reports interpretation literature; Haas D extensive analytic spectroscopic tests to confirm chemical composition medication taken by Dow CT...
Increasingly, Johne's disease of ruminants and human Crohn's are regarded as the same infectious disease: paratuberculosis. Mycobacterium avium ss. paratuberculosis (MAP) is cause most commonly linked disease. Humans broadly exposed to MAP in dairy products environment. has been found within granulomas such can stimulate autoantibodies diseases type 1 diabetes (T1D) Hashimoto's thyroiditis. Moreover, beyond T1D, increasingly associated with a host autoimmune diseases. This article suggests...
SPS is characterized by progressive spasmodic muscular rigidity. thought to be an autoimmune disease with a prominent feature of antibodies against glutamic acid decarboxylase (GAD). GAD responsible for the enzymatic conversion (glutamate) into inhibitory neurotransmitter gamma-aminobutyric (GABA). Reduced GABA activity leads increased excitability in central nervous system, resulting muscle rigidity and spasms characteristic SPS. While rare, anti-GAD seen are also much more common disease,...
BCG vaccine has been used for 100 years to prevent tuberculosis. Not all countries, including the United States, adopted initial World Health Organization recommendation use BCG. Moreover, many Western countries that had routinely have discontinued its use. Recent population studies demonstrate lower prevalence of Alzheimer's disease (AD) in with high coverage. Intravesicular instillation is also treat bladder cancer not invaded muscle wall and shown reduce recurrence. Several retrospective...
Abstract: Human endogenous retroviruses (HERV) are remnants of ancient retroviral infections that, over millions years, became integrated into the human genome. While normally inactive, environmental stimuli such as have contributed to transcriptional reactivation HERV promoting pathological conditions including devel-opment autoimmunity, neurodegenerative disease and cancer. What then trigger activation? Mycobacterium avium subspecies paratuberculosis (MAP) is a pluripotent driver disease....
Abstract: Human endogenous retroviruses (HERV) are remnants of ancient retroviral infections that, over millions years, became integrated into the human genome. While normally inactive, environmental stimuli such as have contributed to transcriptional reactivation HERV promoting pathological conditions including development autoimmunity, neurodegenerative disease and cancer. What then trigger activation? Mycobacterium avium subspecies paratuberculosis (MAP) is a pluripotent driver disease....
The neurologic effects of long-COVID are a therapeutic challenge. This article discusses the immunologic manifestations and proposes non-androgenic, synthetic analog dehydroepiandrosterone (DHEA), bromo-epi-androsterone (BEA), as candidate for clinical trials this exigent collection conditions. Moreover, because there is an association between Alzheimer’s disease, evaluation BEA in may serve proxy its effect on neuroinflammatory biomarkers disease that shared with long-COVID.