A5025259520- Chronic Obstructive Pulmonary Disease (COPD) Research
- Healthcare Systems and Public Health
- Human Health and Disease
- Pediatric health and respiratory diseases
- Respiratory Support and Mechanisms
- COVID-19 Clinical Research Studies
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Long-Term Effects of COVID-19
- Asthma and respiratory diseases
- Inhalation and Respiratory Drug Delivery
- Gut microbiota and health
- Acute Myocardial Infarction Research
- Venous Thromboembolism Diagnosis and Management
- Pneumonia and Respiratory Infections
- Pleural and Pulmonary Diseases
Privolzhsky Research Medical University
2020-2025
Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing
2020-2025
Nizhny Novgorod Research Institute of Traumatology and Orthopedics
2024
Hypersensitivity pneumonitis (HP) is an inflammatory and/or fibrotic lung disease that occurs in response to repeated inhalation of broad-spectrum aerosol antigens. The prevalence HP ranges from 0.3 0.9 cases per 100,000 population. basis treatment therapy includes glucocorticoids, immunosuppressants, and antifibrotic drugs. target audience these clinical recommendations are general practitioners, pulmonologists, pathologists, radiologists, medical rehabilitation specialists. Methods. Each...
Chronic obstructive pulmonary disease (COPD) is the third leading cause of death worldwide, with over 30% these patients dying from cardiovascular diseases. Objective: to study pathophysiological links between echocardiography, spirometry indicators, and inflammatory biomarkers in various clinical phenotypes occupational COPD comorbidity. Material methods. The included 111 Based on results, were divided into 4 groups (clinical phenotypes). Clinical examinations, serum concentrations troponin...
Chronic obstructive pulmonary disease (COPD) is a progressing disease. Each exacerbation impairs the patient’s prognosis and increases burden for healthcare system. The most common maintenance treatment options COPD include long-acting bronchodilators – β2-agonists (LABA) antimuscarinic agents (LAMA), inhaled glucocorticosteroids (ICS), in fixed/opened double triple combinations. Triple therapy subjects with history effective way to prevent negative outcomes of It can reduce frequency...
Chronic obstructive pulmonary disease (COPD) is a progressing disease. Each exacerbation impairs the patient’s prognosis and increases burden for healthcare system. The most common maintenance treatment options COPD include long-acting bronchodilators – β2-agonists (LABA) antimuscarinic agents (LAMA), inhaled glucocorticosteroids (ICS), in fixed/opened double triple combinations. Triple therapy subjects with history effective way to prevent negative outcomes of It can reduce frequency...
Currently there is no convincing evidence concerning pathogenetic mechanisms of fibrous and sclerotic processes in pulmonary tissue as well bronchopulmonary system remodeling patients with chronic obstructive disease (COPD) occupation etiology (OE). The purpose the study was to identify relationship between serum hyaluronic acid (HA) level severity ventilation impairment according spirometry data subjects COPD associated impact silica-containing dust occupational non-obstructive (common)...
The specific features of the course chronic occupational bronchitis (OCB) and its relationships with obstructive pulmonary disease (OCOPD) have not been adequately investigated in clinic pathology. aim study was to risk factors, clinical prognosis non-obstructive bronchitis. 222 patients (metal workers) OCB OCOPD were randomly selected for study. medical histories diseases studied from initial diagnosis present status (in average period 10 years). Patients divided into three groups: (1),...
Introduction. The pathogenetic differences between the phenotypes of occupational chronic obstructive pulmonary disease which develop after silica-containing dust exposure are still unclear. research aims to study relationship clinical with inflammation. Material and methods. 123 patients were included in study. Basing on forced expiratory volume 1 second, symptoms history exacerbations, divided into 4 groups (group - 30 people (24%) phenotype «B1», group 2 16 «B2» (13%), 3 32 (26%) «D», 45...
Aim. To evaluate the impact of chronic obstructive pulmonary disease (COPD) on hospital outcomes percutaneous coronary interventions (PCI) in patients with acute syndrome (ACS).
 Materials and methods. A cohort prospective study COPD effect mortality microvascular obstruction (CMVO, no-reflow) development after PCI ACS was carried out. 626 admitted 2019–2020 were included, 418 (67%) – men, 208 (33%) women. Median age 63 [56; 70] years. Myocardial infarction ST elevation identified 308...
The aim of the study was to analyze trends spirometry changes in occupational chronic bronchitis patients during period 10 years. It found out that 34,1% 158 had transformed into obstructive pulmonary disease, regardless history smoking.
The frequency of exacerbations chronic obstructive pulmonary disease (COPD) is one the main factors determining outcome. search for biomarkers which reflect risk urgent scientific and practical objectives. Aim . study aimed to analyze relationship between serum concentration hyaluronic acid (HA) occupational COPD caused by exposure silica dust substantiate use HA as a predictor COPD. Methods 78 individuals with diagnosis were examined. Respiratory function was assessed based on forced vital...
The aim of the study was to analyze data from real clinical practice diagnosis and treatment a new coronavirus infection obtained during first wave virus in Nizhny Novgorod Region.
Background. Since December 2019 there has been a rapid spread of the COVID-19 pandemic across most world. This determined enormous burden on global economy. The new coronavirus infection is not only by costs directly related to treatment acute phase disease, but also successful rehabilitation patients after COVID-19, risk reduction and timely management adverse outcomes for optimal patient recovery. Aim. aim study was analyze estimate possibility their correction prevention. Material...
The development of new methods for diagnosing infectious diseases, such as polymerase chain reaction, sequencing, and mass spectrometry, has made it possible to expand our understanding the microflora human body in general respiratory tract particular. most common microorganisms lungs include Proteobacteria (Pseudomonas spp., Haemophilus spp.), Bacteriodetes (Prevotella Porphyromonas spp.) Firmicutes (Veillonella Streptococcus spp.). Pathological processes lower change microbiome....