A5081877199- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Crystallography and molecular interactions
- Chemical and Physical Properties in Aqueous Solutions
- Analytical Chemistry and Chromatography
- Luminescence and Fluorescent Materials
- Drug Solubulity and Delivery Systems
- Pharmacological Effects of Natural Compounds
- Phase Equilibria and Thermodynamics
- Calcium Carbonate Crystallization and Inhibition
- Nonlinear Optical Materials Research
- nanoparticles nucleation surface interactions
- Chemical Thermodynamics and Molecular Structure
- Surfactants and Colloidal Systems
- Innovative Microfluidic and Catalytic Techniques Innovation
- Protein purification and stability
- Computational Drug Discovery Methods
- Phenothiazines and Benzothiazines Synthesis and Activities
- Food Chemistry and Fat Analysis
- Enzyme Structure and Function
- Freezing and Crystallization Processes
- Photochromic and Fluorescence Chemistry
- Thermal and Kinetic Analysis
- Crystal structures of chemical compounds
- Proteins in Food Systems
Tianjin University
2016-2025
State Key Laboratory of Chemical Engineering
2016-2025
Unité Matériaux et Transformations
2022-2025
Collaborative Innovation Center of Chemical Science and Engineering Tianjin
2015-2024
Qinghai University
2023
Shaoxing University
2022
Qinghai University for Nationalities
2021
Tianjin Institute of Pharmaceutical Research (China)
2019-2021
Ji Hua Laboratory
2021
National Center of Ocean Standards and Metrology
2019
Crystallization, as a solid–liquid separation process, is employed to purify and isolate great diversity of crystalline pharmaceutical products. In recent years, continuous crystallization has attracted increasing attention because the product process robustness well higher productivity. this work, we review use novel crystallizers or modified conventional for preparation polymorphs, chiral enantiomers, solvates/hydrates, cocrystals, spherical crystals. addition, theoretical framework...
Carbon-based sensors for the detection of ascorbic acid (AA) and ferric ions have drawn a great deal attention recently, owing to their excellent optical properties good biocompatibility biological applications. In this work, series nitrogen-doped carbon dots (NCDs) were fabricated by microwave-assistant approach with combination dl-malic urea as precursors. Under optimal experimental conditions, NCDs an average size 4.52 ± 0.05 nm prepared, containing amino N C–N functional groups on...
Abstract Various mechanical effects have been reported with molecular materials, yet organic crystals capable of multiple dynamic are rare, and at present, their performance is worse than some the common actuators. Here, we report a confluence different across three polymorphs an crystal that can efficiently convert light into work. Upon photodimerization, acicular polymorph I display output work densities about 0.06–3.94 kJ m −3 , comparable to ceramic piezoelectric Prismatic same form...
The solubility of sorafenib free base (SFB) and tosylate (ST) in five monosolvents binary solvents 2-propanol + 1,4-dioxane was measured over the temperature ranged from 283.15 to 333.15 K by using a UV spectroscopy method. SFB ST different increases with increasing temperature, while solvents, shows maximum value at 0.50 0.75 mole fraction for ST, respectively. Apelblat model CNIBS/R-K were applied correlate data, which that two selected thermodynamic models could give satisfactory results....
Understanding the structural origins of diverse mechanical behaviors organic crystals is critical for designing functional materials a number technological applications. To facilitate this effort, we have examined two polymorphs structurally rigid molecule, coumarin. Surprisingly, form I are highly elastic while II two-dimensional (2D) plastic and twistable. The strikingly different corroborate with respective prevailing mechanisms, i.e., high elasticity enabled by an interlocked layer...
In this paper, the crystallization of L-glutamic acid with application ultrasound was explored in detail, including process nucleation, polymorphic control and transformation. The induction time metastable zone widths (MSZWs) were measured without during nucleation process. MSZWs decreased by further higher ultrasonic power. calculated parameters (such as interfacial energy, critical nucleus size Gibbs energy) showed an obvious decrease presence ultrasound, indicating that enhanced...
The solubility of 5,5-dimethylhydantoin (DMH) in 12 pure solvents including water, methanol, ethanol, 1-propanol, isopropyl alcohol, 1-butanol, isobutyl 2-butanol, 1-pentanol, ethyl acetate, propyl and acetonitrile was measured at temperatures from 283.15 to 323.15 K under atmospheric pressure by a gravimetric method. values the mole fraction DMH these increase with increasing temperature present following order fixed temperature: methanol > ethanol 2-butanol alcohol 1-propanol (1-butanol)...
Abstract Dynamic molecular crystals are thought to be an emerging functional material with enormous tunability in physicochemical properties. Here, a smart crystal, 6‐Chloronicotinic acid (6‐CNA), is reported, responding heat stimulus by bending, splitting‐to‐self‐healing, and jumping, induced thermally reversible single‐crystal‐to‐single‐crystal phase transition. This transition proceeds well‐organized migration of the habit plane, which reproducible after more than twenty cycles. The...
Mechanical flexible organic crystals with optical properties have attracted increasing research interest, because of their unusual phenomena and broad application prospects. However, achieving both plasticity luminescent in is difficult. Here we report a plastic crystal, flufenamic acid (FFA) form III which shows highly bending along (001) face hand-twistable behavior under applied external force. It also illustrated unique mechanofluorochromism behavior. In summary, the proposed soft single...
Deciphering the effect of small changes in crystal packing and intermolecular interactions on type magnitude mechanical motion is central to manipulation macrodynamic behavior dynamic crystals as smart materials. Here, we describe a peculiar example where both flexibility photomechanical molecular can be altered by single chemical substitution. Specifically, demonstrate that an organic switches from plastic bending elastic/plastic changing functional group thiophene ring methyl (crystal 1)...