A5072186994- Gastric Cancer Management and Outcomes
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Metastasis and carcinoma case studies
- Enhanced Recovery After Surgery
- Radiomics and Machine Learning in Medical Imaging
- Gastrointestinal Tumor Research and Treatment
- RNA modifications and cancer
- Pancreatic and Hepatic Oncology Research
- Nutrition and Health in Aging
- Colorectal Cancer Screening and Detection
- Cancer-related molecular mechanisms research
- Cell Adhesion Molecules Research
- Stoma care and complications
- Innovative Microfluidic and Catalytic Techniques Innovation
- Nanomaterials for catalytic reactions
- Mental Health Research Topics
- Advanced biosensing and bioanalysis techniques
- Esophageal and GI Pathology
- Advanced Graph Neural Networks
- Graph Theory and Algorithms
- Frailty in Older Adults
- RNA Research and Splicing
- Congenital Anomalies and Fetal Surgery
- Functional Brain Connectivity Studies
Qingdao University
2019-2025
Affiliated Hospital of Qingdao University
2019-2025
Wenzhou Medical University
2024-2025
Jiangsu Hengrui Medicine (China)
2025
Jilin University
2024
State Key Laboratory of Inorganic Synthesis and Preparative Chemistry
2024
Second Affiliated Hospital of Fujian Medical University
2024
Fujian Medical University
2024
Jinzhou Kangning Hospital
2024
Xinjiang University
2024
To assess the efficacy/safety of ivarmacitinib, a selective Janus kinase (JAK) 1 inhibitor, in patients with moderate-to-severe active rheumatoid arthritis (RA) who had an inadequate response to conventional synthetic disease-modifying antirheumatic drugs (csDMARDs). Patients were randomised (1:1:1) receive either placebo (n=188), ivarmacitinib 4 mg (n=189) or 8 once daily, background csDMARDs allowed. After 24 weeks, on switched for additional 28 while those continued their initial dosage....
Abstract Background Although current guidelines(ESPEN guideline: Clinical nutrition in surgery and other guidelines) recommend preoperative immunonutrition for cachectic gastric cancer patients, the strength of recommendation is weak, level evidence low. The benefits still remain controversial. Patients methods 112 patients with cachexia were enrolled study randomly assigned a 1:1 ratio to receive either enteral support (IN, n = 56) or standard (SEN, 56). primary endpoint was incidence...
Polyamidoamine dendrimers, which can deliver drugs and genetic materials to resistant cells, are attracting increased research attention, but their transportation behavior in cells remains unclear. In this paper, we performed a systematic analysis of the cellular uptake, intracellular transportation, efflux PAMAM-NH2 dendrimers multidrug-resistant breast cancer (MCF-7/ADR cells) using sensitive (MCF-7 as control. We found that uptake rate was much lower exocytosis greater MCF-7/ADR than...
Purpose: Transcutaneous electrical acupoint stimulation (TEAS) is an innovative choice for postoperative pain management. However, the safety and effectiveness of this traditional Chinese medicine (TCM) therapy patients who underwent gastrectomy largely unknown. So, purpose study to evaluate TEAS gastrectomy. Patients Methods: We recruited 96 with gastric cancer from May 2019 November 2019; 82 were enrolled, 81 completed. randomly assigned group (TG) received on day (POD) 1– 3 or control...
Background With the increasing number of cancer treatments, emergence multidisciplinary teams (MDTs) provides patients with personalized treatment options. In recent years, artificial intelligence (AI) has developed rapidly in medical field. There been a gradual tendency to replace traditional diagnosis and AI. IBM Watson for Oncology (WFO) proven be useful decision-making breast lung cancer, but date, research on gastric is limited. Objective This study compared concordance WFO MDT...
The mechanisms by which the tumor behaviors of hepatocellular carcinoma (HCC) support growth and metastasis remain largely unknown, it has become increasingly apparent that molecular dysregulation is considerable importance for cellular signaling pathways. Recently, RNA-binding motif protein 47 (RBM47) been suggested to function as a regulator acting an RNA binding (RBP), but its role in HCC remains ambiguous. Here, HCC, we identified RBM47 had inhibitory influence on vitro accordingly...
Abstract Background Studies on robotic total gastrectomy (RTG) are currently limited. This study aimed to compare the intraoperative performance as well short‐ and long‐term outcomes of RTG laparoscopic (LTG). Methods A 969 patients underwent ( n = 161) or 636) between October 2014 2021. The two groups were matched 1:3 using propensity score matching (PSM) method. 147) 371) compared. Results After matching, estimated blood loss was lower (80.51 ± 68.77 vs. 89.89 66.12, p 0.008), number lymph...
Graph Neural Networks (GNNs) have recently gained widespread attention as a successful tool for analyzing graph-structured data. However, imperfect graph structure with noisy links lacks enough robustness and may damage representations, therefore limiting the GNNs' performance in practical tasks. Moreover, existing generative architectures fail to fit discriminative graph-related To tackle these issues, we introduce an unsupervised method based on joint of training learn representation,...
BACKGROUND At present, the enhanced recovery after surgery (ERAS) protocol is widely implemented in field of gastric surgery. However, effect ERAS on long-term prognosis cancer has not been reported. AIM To compare effects and conventional protocols short-term outcomes laparoscopic gastrectomy. METHODS We retrospectively analyzed data 1026 consecutive patients who underwent gastrectomy between 2012 2015. The were divided into either an group or a group. groups matched 1:1 ratio using...
Introduction Gastric cancer (GC) diagnosed in the elderly population has become a serious public health problem worldwide. Given combined effects of frailty and consequences treatment, older individuals with GC are more likely than young patients to suffer from postoperative complications poor clinical outcomes. Nutrition, functional capacity psychological state-based multimodal prehabilitation, which is dominated by Enhanced Recovery After Surgery (ERAS) pathway management, been shown...
Objective With the rising global obesity rates, increasing research has been directed toward understanding how affects cognitive ability in young adults. This study aims to explore impact of body mass index (BMI) on general and sleep quality impulsive trait mediate this relationship. Methods A total 1,205 adults from Human Connectome Project(HCP) project were included, questionnaires assessment tools conducted. Results BMI was negatively correlated with ability, acting as chain mediators...
Abstract Background Depression is a significant issue affecting adolescents’ mental health. While depression research relatively extensive, studies focusing on left-behind adolescents from single-parent families remain limited. Due to their unique family structure, this group more susceptible multiple stressors, increasing risk of depression. Objective This study aims construct predictive model based nomogram identify the multidimensional characteristics among families, providing theoretical...
To evaluate the multiple factors influencing survival of elderly patients with locally advanced gastric cancer (LAGC) and develop validate novel nomograms for predicting survival.The clinical features treated between 2000 2018 were collected collated from Surveillance, Epidemiology, End Results (SEER) database three medical centres in China, randomly divided into a training cohort (3494), internal validation (1497) external (841). Univariate multivariate analyses prognostic values performed...
Background The present study investigate the expression and correlation of ITGB6 Rac1 proteins in gastric cancer tissues. By exploring clinical significance functions these proteins, we aimed to gain further insights into mechanisms underlying development. Patients methods In this study, a total 198 patients diagnosed with who underwent gastrectomy between July 2010 October 2012 were included. median follow-up time was 52.00 months. To evaluate factors influencing overall survival,...
Abstract The controlled regulation of A‐site in rare earth manganate perovskites can orderly arrange the electronic states, leading to emergence unique transport properties. However, it is challenging balance crystal structure stability and property variations during multi‐ion doping. In this study, a series multivalent are synthesized by hydrothermal method through multielement doping, which enables manganese atoms with varying valence states at B site. Powder X‐ray diffraction (PXRD)...
The purpose of this study was to identify long noncoding RNAs (lncRNAs) related prognosis patients with colorectal cancer (CRC) and develop a prognostic prediction model for CRC. Transcriptome data survival information CRC were downloaded from Cancer Genome Atlas. differentially expressed lncRNAs (DElncRNAs) between normal tissues identified by the edgeR package. association DElncRNAs expression analyzed A nomogram predicting 3- 5- year overall drawn rms total 1046 identified, including 271...