A5072594090- Cell Adhesion Molecules Research
- Chemical Synthesis and Analysis
- Trauma Management and Diagnosis
- Wound Healing and Treatments
- Estrogen and related hormone effects
- HER2/EGFR in Cancer Research
- Glycosylation and Glycoproteins Research
- Signaling Pathways in Disease
- Genomics and Chromatin Dynamics
- Pelvic floor disorders treatments
- Rabies epidemiology and control
- Biochemical and Structural Characterization
- Abdominal Trauma and Injuries
- Click Chemistry and Applications
- Shoulder and Clavicle Injuries
- Neurobiology and Insect Physiology Research
- Protein Degradation and Inhibitors
- Nuclear Structure and Function
- Streptococcal Infections and Treatments
- Proteoglycans and glycosaminoglycans research
- Neuroendocrine regulation and behavior
- Caveolin-1 and cellular processes
- Trauma and Emergency Care Studies
- Prostate Cancer Treatment and Research
- RNA modifications and cancer
Albany Medical Center Hospital
2004-2022
The Schwarzman Animal Medical Center
2018
Abstract: A synthetic peptide that inhibits the growth of estrogen receptor positive (ER+) human breast cancers, growing as xenografts in mice, has been reported. The cyclic 9‐mer peptide, cyclo [EMTOVNOGQ], is derived from α ‐fetoprotein (AFP), a safe, naturally occurring protein produced during pregnancy, which itself anti‐estrogenic and anti‐breast cancer activity. To determine pharmacophore series analogs was prepared using solid‐phase synthesis. Analogs were screened 1‐day bioassay,...
Purpose: The antegrade continence enema (ACE) is an option in the management of fecal incontinence and chronic constipation. We report our experience with a simple laparoscopic technique. Subjects Methods: Data were collected on 16 children (8 boys) who underwent cecostomy for ACE. Success was defined as cessation soiling no need diapers. Results: Mean age at 11 years (range, 6–16 years). follow-up after initial 22 months 6–51 months). Diagnoses patients functional constipation (n=14),...
Tamoxifen (Tam) is effective for the treatment and prevention of breast cancer. However, it has toxic drawbacks limited-duration utility because, over time, human tumours become refractory to Tam. Recently, a new nontoxic peptide, α-fetoprotein-derived peptide (AFPep) been proposed The purpose this paper determine whether combining AFPep with Tam would increase efficacy reduce toxicity in experimental models Low doses were more combination than either agent alone against cancer growth cell...
Pasteurella multocida is a common cause of soft tissue infections in humans and usually results from bite by domestic or wild animal. supraglottitis rare likely non-bite animal exposure. We report case P. resulting bacteremia seeding vascular homograft pseudoaneurysm formation. After surgical repair the graft 6 weeks postoperative antibiotic therapy, patient resumed normal activities has continued to do well after 1 year follow-up. This illustrates potential for non-bite–associated...
Introduction: Prolonged emergency department (ED) stays for critically ill trauma intensive care unit (ICU) bound patients have been associated with increased rates of infection and morbidity decreased qualify care. Health systems developed specific guidelines designed to rapidly transfer non-operative from the ED surgical ICU (SICU). These produced shorter times mixed results on mortality limited evaluation common outcomes. Using largest cohort date, we anticipate stays, mechanical...