Xiao‐Pei Zhang

ORCID: 0000-0003-4350-0972
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About
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Research Areas
  • Acute Ischemic Stroke Management
  • Stroke Rehabilitation and Recovery
  • Dementia and Cognitive Impairment Research
  • Blood Pressure and Hypertension Studies
  • Retinal Diseases and Treatments
  • Health and Wellbeing Research
  • Dysphagia Assessment and Management
  • Intracerebral and Subarachnoid Hemorrhage Research
  • Intraocular Surgery and Lenses
  • Ophthalmology and Visual Impairment Studies
  • Nanoplatforms for cancer theranostics
  • Cardiovascular Health and Risk Factors
  • Esophageal and GI Pathology
  • Tracheal and airway disorders
  • Cardiac Ischemia and Reperfusion
  • Non-Invasive Vital Sign Monitoring
  • Corneal surgery and disorders
  • Nosocomial Infections in ICU
  • Corneal Surgery and Treatments
  • Nanoparticle-Based Drug Delivery
  • Cardiac Arrest and Resuscitation
  • Frailty in Older Adults
  • Intracranial Aneurysms: Treatment and Complications
  • Heart Rate Variability and Autonomic Control
  • Cardiovascular Health and Disease Prevention

Guangzhou University of Chinese Medicine
2017-2024

Guangdong Provincial Hospital of Traditional Chinese Medicine
2021-2023

Sun Yat-sen University
2021

E Ink (South Korea)
2021

National Natural Science Foundation of China
2021

Third Affiliated Hospital of Sun Yat-sen University
2021

Nanjing Medical University
2018-2020

Purpose: Antiangiogenic drugs usually have short-acting efficacy and poor treatment compliance.The purpose of this study was to determine whether mesoporous silica nanoparticles (MSNs) could be utilized as a nanodrug delivery system for improving antiangiogenic therapy.Materials methods: MSN-encapsulated bevacizumab were prepared by the nanocasting strategy characterized Fourier transform infrared, transmission electron microscopy, Brunauer-Emmett-Teller method.Encapsulation efficiency drug...

10.2147/ijn.s195504 article EN cc-by-nc International Journal of Nanomedicine 2019-02-01

The health behaviors of hypertensive stroke patients in China are not satisfactory. In this study, we tested the effect a Health Belief Model Comprehensive Reminder System on and blood pressure control ischemic after occurrence hospital discharge.A randomized, parallel-group, assessor-blinded experimental design yielded participation 174 hospitalized patients. intervention consisted face-to-face telephone belief education, patient calendar handbook, weekly automated short-message services....

10.1097/jcn.0000000000000496 article EN The Journal of Cardiovascular Nursing 2018-06-13

Pulmonary infection is a frequent complication among stroke patients and adversely affects clinical outcomes, increases the length of hospitalization stay costs, aggravates financial burden national medical health system. Early identification management high-risk are necessary imperative to reduce incidence stroke-associated pneumonia (SAP).The evidence-based practice project evaluated effectiveness standard care bundle intervention in preventing occurrence SAP.The was conducted neurology...

10.1186/s12883-022-02826-8 article EN cc-by BMC Neurology 2022-08-11

Individuals with hypertension are at risk of stroke, and patients stroke histories experiencing another stroke. At this time, however, only a few studies have reported on prevention knowledge health behaviors among hypertensive who had an initial The purpose study was to determine analyze the association between these 2 variables stroke.With use descriptive correlational design, sample 112 recruited from departments neurology 3 hospitals in Guangzhou, China. Each patient completed reliable,...

10.1097/jcn.0b013e31827f0ab5 article EN The Journal of Cardiovascular Nursing 2013-07-04

Background: Prehospital delay, defined as prehospital time (from symptom onset to hospital arrival) ≥3 hours, adversely affects outcomes in patients with acute ischemic stroke. It is prevalent both among first-time and recurrent stroke, who differ disease psychological characteristics affecting their health-seeking behavior. However, comparative studies on delay-related factors between these groups are limited. Objectives: We aimed identify compare influencing delay Methods: This 2-center,...

10.1177/01939459251340778 article EN Western Journal of Nursing Research 2025-05-24

Dysphagia is common after stroke. Patients with dysphagia have a higher risk of stroke-associated pneumonia (SAP) and poor outcomes. Early detection necessary to identify manage patients at high aspiration. The aim the study was assess impact systematic administration volume-viscosity swallow test (V-VST) in acute ischaemic stroke.This retrospective observational that enrolled stroke two consecutive time periods: pre-V-VST, when 30-mL water-swallowing (WST) systematically administered,...

10.1186/s12883-020-01733-0 article EN cc-by BMC Neurology 2020-04-25

To test prospective pathways of a Comprehensive Reminder System based on the Health Belief Model (CRS-HBM), stroke knowledge, health belief in behaviour, blood pressure (BP) control, and disability hypertensive ischaemic patients at 6-month postdischarge.A nested cohort study design.Data were derived from randomized controlled trial evaluating effects intervention (N = 174, performed during February 2015 - March 2016). Data collected by questionnaires analysed structural equation modelling...

10.1111/jan.14340 article EN Journal of Advanced Nursing 2020-03-04

BACKGROUND: Previous research has shown that men and women have different levels of stroke knowledge differing health behaviors, which are important factors affecting blood pressure, as hypertension is a key risk factor for occurrence. There been little on the effects sex association between these 2 variables before onset among Chinese hypertensive patients. METHODS: A cross-sectional study convenience sampling method were used. 272 male 118 female patients recruited. Each patient completed...

10.1097/jnn.0000000000000599 article EN Journal of Neuroscience Nursing 2021-06-10

Renal function is associated with mortality and functional disabilities in stroke patients, impaired autonomic common stroke, but little known regarding its effects on patients renal dysfunction. This study sought to evaluate the association between dysfunction.This comprised 232 acute ischemic consecutively enrolled from February 2013 November 2014 at Guangdong Provincial Hospital of Chinese Medicine China. All recruited underwent laboratory evaluation 24 h Holter electrocardiography (ECG)....

10.4103/0366-6999.201599 article EN cc-by-nc-nd Chinese Medical Journal 2017-03-06

Pre-hospital delay refers to the time span from onset of symptoms arrival at a hospital ≥ 3 h and is main limitation stroke reperfusion therapies. Family factors stroke-related stigma may influence pre-hospital delay. However, few studies have confirmed on or explored relationships between family function, stigma, among patients with recurrent stroke. This study aimed explore relationship function examine mediation role in this relationship.A cross-sectional was performed neurology...

10.1093/eurjcn/zvad001 article EN European Journal of Cardiovascular Nursing 2023-01-05

Aims To investigate the association between pre-stroke frailty and discharge destination in hospitalized older adults China.

10.1080/10749357.2024.2448392 article EN Topics in Stroke Rehabilitation 2024-12-30

Abstract Background There were 28.76 million stroke patients in China, with 3.94 new strokes annually. Around 70% of survivors live varying degrees permanent disability, placing a heavy burden on families and society. Stroke have complex high need for continuing care services after discharge from the hospital. The study was to evaluate effectiveness program activity daily life, degree recurrence readmission stroke, based long-term insurance policy. Methods Eighty-eight recruited February...

10.21203/rs.3.rs-2580359/v1 preprint EN cc-by Research Square (Research Square) 2023-03-13
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