Keshav Sharma

ORCID: 0000-0003-4353-817X
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About
Contact & Profiles
Research Areas
  • SARS-CoV-2 and COVID-19 Research
  • HIV/AIDS Impact and Responses
  • Urological Disorders and Treatments
  • Hidradenitis Suppurativa and Treatments
  • COVID-19 Clinical Research Studies
  • Human Rights and Development
  • HIV Research and Treatment
  • Gastrointestinal disorders and treatments
  • Colorectal and Anal Carcinomas
  • Microscopic Colitis
  • Kidney Stones and Urolithiasis Treatments
  • Immune Cell Function and Interaction
  • Ureteral procedures and complications
  • Advanced Malware Detection Techniques
  • Long-Term Effects of COVID-19
  • Inflammatory Bowel Disease
  • COVID-19 diagnosis using AI
  • Urologic and reproductive health conditions
  • Academic Publishing and Open Access
  • Spatial Cognition and Navigation
  • Electric and Hybrid Vehicle Technologies
  • Ultrasound and Cavitation Phenomena
  • Quantum-Dot Cellular Automata
  • Sirtuins and Resveratrol in Medicine
  • Lymphatic Disorders and Treatments

Wayne State University
2025

Icahn School of Medicine at Mount Sinai
2020-2024

Post Graduate Institute of Medical Education and Research
2021-2024

Jawaharlal Nehru Medical College
2024

ABES Engineering College
2024

Graphic Era University
2023

Banaras Hindu University
2020-2023

Sharda University
2023

Marymount University
2023

Creative Commons
2022

Vedolizumab (VDZ) is a first-line treatment in ulcerative colitis (UC) that targets the α4β7- mucosal vascular addressin cell adhesion molecule 1 (MAdCAM-1) axis. To determine mechanisms of action VDZ, we examined five distinct cohorts patients with UC. A decrease naïve B and T cells intestines gut-homing (β7 + ) plasmablasts circulation VDZ-treated suggested VDZ gut-associated lymphoid tissue (GALT). Anti-α4β7 blockade wild-type photoconvertible (KikGR) mice confirmed loss GALT size...

10.1126/sciimmunol.adg7549 article EN mit Science Immunology 2024-04-19

Abstract Given that gastrointestinal (GI) symptoms are a prominent extrapulmonary manifestation of coronavirus disease 2019 (COVID-19), we investigated the impact GI infection on pathogenesis in three large cohorts patients United States and Europe. Unexpectedly, observed involvement was associated with significant reduction severity mortality, an accompanying key inflammatory proteins including IL-6, CXCL8, IL-17A CCL28 circulation. In fourth cohort COVID-19 which biopsies were obtained,...

10.1101/2020.09.07.20187666 preprint EN medRxiv (Cold Spring Harbor Laboratory) 2020-09-09

Abstract Head and neck cancers (HNCs) are becoming more common, thereby gaining greater attention within the medical community. This retrospective trend analysis examined geographical access to HNC clinical trials in United States from 2005 2024, utilizing Census data Haversine formula. A search of ClinicalTrials.gov identified 23,450 trial sites, with 18,394 initiated before 2020. Although linear regression revealed a slight annual increase initiation (37.947 trials/year, R ² = 0.014, P...

10.1002/ohn.1168 article EN Otolaryngology 2025-02-14

In the lower urinary tract, calculi are usually observed in bladder, prostate, and urethral locations. Here, we present case of a 40-year-old laborer male patient who presented with complaints dribbling urine off on, suprapubic pain for 1 week, feeling stone at meatus 4.5 years. X-ray pelvis was suggestive long slender near meatus. Kidney ureter bladder ultrasonography suggest no upper tract changes large capacity increased post-void residual. The managed surgically under spinal anesthesia....

10.32677/ijcr.v11i2.4895 article EN Indian Journal of Case Reports 2025-03-13

Abstract Objective Otolaryngology‐related conditions impose a significant burden on low‐income countries (LICs), lower‐middle‐income (LMICs), and, at times, upper‐middle‐income (UMICs), where health care resources are limited. International research collaboration with high‐income (HICs), like the United States, can address these disparities by advancing global knowledge. As such, underlying objective was to define trends of collaborative otolaryngology publications among States and LICs,...

10.1002/ohn.1266 article EN Otolaryngology 2025-04-18

With the increasing use of Internet Things (IoT)-enabled drones for various purposes, including photography, delivery, and surveillance, concerns related to privacy security have arisen. Drones potential capture sensitive information, invade privacy, cause breaches. Therefore, need advanced technology automated detection has become crucial. In this paper, we propose an ensemble-based IoT-enabled scheme (in short, EDDSBS). The presented model is part a computer vision-based module uses...

10.1109/ojcoms.2023.3310003 article EN cc-by IEEE Open Journal of the Communications Society 2023-01-01

Abstract Skin is now emerging as a complex realm of three chief systems viz. immune system, nervous and endocrine system. The cells involved in their intricate crosstalk, namely native skin cells, intra‐cutaneous cutaneous sensory neurons have diverse origin distinct functions. However, recent studies explored role beyond pre‐defined functional boundaries, such that the shun traditional functions adopt unconventional roles. For example, apart from providing for basic structural framework...

10.1111/exd.15029 article EN Experimental Dermatology 2024-03-01

This paper proposes a new technique that enables open innovation in mobile platforms. Our allows third-party developers to modify, instrument, or extend platform API calls and deploy their modifications seamlessly. The uniqueness of our is it completely at the app layer without requiring any platform-level changes. practical openness---third parties can easily distribute for need update entire platform. To demonstrate benefits technique, we have developed prototype on Android called Reptor...

10.1145/3081333.3081341 article EN 2017-06-16

10.4103/ijd.ijd_594_22 article EN cc-by-nc-sa Indian Journal of Dermatology 2023-05-01

Renewable energy extraction and electric vehicle use have made cleaner transportation possible. Electric vehicles' battery charging is a problem nowadays. We can reduce our reliance on fossil fuels by EV batteries using solar energy. The panel's current voltage fluctuate with the weather. vehicles need fast charging. Charging times may be reduced when high currents voltages are used. However, at excessive or damage battery. Battery safety requires careful consideration of methods in order to...

10.1109/ic2pct60090.2024.10486465 article EN 2024-02-09

Abstract Gastrointestinal (GI) B cells and plasma (PCs) are critical to mucosal homeostasis the host response HIV-1 infection. Here, high resolution mapping of human PCs sampled from colon ileum during both viremic suppressed infection identified a reduction in germinal center (GC) follicular dendritic (FDCs) viremia. IgA + major cellular output intestinal GCs were significantly reduced PC-associated transcriptional perturbations, including type I interferon signaling, persisted...

10.1101/2024.05.17.590425 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2024-05-20

An 18-year-old man presented to the emergency department of a community hospital with cough, fever, night sweats and significant weight loss. He recently completed an antibiotic course for lower respiratory-tract infection. Full blood count revealed normal total white cell eosinophil 0.85×109/L. C-reactive protein (CRP) was but erythrocyte sedimentation rate (ESR) 100 mm/hour. Chest radiograph demonstrated bilateral perihilar reticulonodular opacification peripheral sparing (figure 1A)....

10.1136/thoraxjnl-2020-214762 article EN Thorax 2020-05-15

A 57-year-old man noticed a painless bluish mass enlarging on top of his right foot. Fine-needle aspiration and excisional biopsy showed high-grade giant-cell variant malignant fibrous histiocytoma. Because he had recurrence the tumour at initial excision site within 2 months,

10.1503/cmaj.045195 article EN cc-by-nc-nd Canadian Medical Association Journal 2005-04-25

Abstract Although clinicians and researchers have long appreciated the detrimental effects of excessive acute inflammation after myocardial infarction (MI), less is known about role adaptive immune system in MI complications including heart failure. Yet, abundant cardiac self-antigens released from necrotic cardiomyocytes a highly inflammatory environment are likely to overwhelm peripheral mechanisms immunological self-tolerance auto-reactivity against may cause ongoing tissue destruction...

10.1101/542597 preprint EN cc-by bioRxiv (Cold Spring Harbor Laboratory) 2019-02-18

Abstract: In the current corporate and educational environment canteen plays a crucial role in feeding nutritional needs of employees students but looking forward to traditional management system lacks various ways like long waiting queues, inefficiency, resource wastage, scalability issues many more problems. To address this issue research proposes Canteen-Circuit, solution that uses MERN stack AI provide seamless connection for both staff customers. The Research will involve designing,...

10.22214/ijraset.2024.62466 article EN International Journal for Research in Applied Science and Engineering Technology 2024-05-23

Background: Urethral stricture disease is the most common cause of obstructive voiding symptoms in younger males and has always been a challenge for urologists. Optical urethrotomy (OU) considered as standard therapy anterior urethral short segments strictures. Methods: In our study 164 consecutive treatment naive recurrent patients who underwent direct vision internal (DVIU) were retrospectively analyzed. 22Fr catheters placed longer durations small calibre (14 or 16Fr) preferred shorter...

10.18203/2320-6012.ijrms20244119 article EN International Journal of Research in Medical Sciences 2024-12-31

In the prevailing scenario, Net banking plays an essential role in economic development. However, with increasing significance of digital versions facilities, frauds and scams are exceptionally rising. Moreover, The existing portal government banks does not provide complete information to their customers regarding various schemes investment policies. This paper proposes upgraded design current system. It will make online reliable much more efficient. A verification link is sent via Firebase...

10.1109/i2ct54291.2022.9825468 article EN 2022 IEEE 7th International conference for Convergence in Technology (I2CT) 2022-04-07
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