A5108035790- Tuberculosis Research and Epidemiology
- Mycobacterium research and diagnosis
- Plant Molecular Biology Research
- Photosynthetic Processes and Mechanisms
- Light effects on plants
- Plant Parasitism and Resistance
- Immune Cell Function and Interaction
- interferon and immune responses
Bengbu Medical College
2023-2024
Hokkaido University
2024
Background Mycobacterium tuberculosis antigen (Mtb-Ag) is a polypeptide component with molecular weight of 10-14 kDa that obtained from the supernatant H37Ra strain after heat treatment. It stimulates activation and proliferation γδT cells in blood to produce an immune response against tuberculosis. Mtb-Ag therefore crucial for classifying detecting central genes key pathways involved TB initiation progression. Methods In this study, we performed high-throughput RNA sequencing peripheral...
Abstract Root development is essential for plant survival. The lack of carotenoid biosynthesis in the phytoene desaturase 3 (pds3) mutant results short primary roots (PRs) and reduced lateral root formation. In this study, we showed that short-term inhibition PDS by fluridone suppresses PR growth wild type, but to a lesser extent auxin mutants Arabidopsis (Arabidopsis thaliana). Such an activity increased endogenous indole-3-acetic acid levels, promoted signaling, partially complemented...
Abstract Background Mycobacterium tuberculosis heat-resistant antigen (Mtb-HAg) is a peptide released from the mycobacterial cytoplasm into supernatant of (Mtb) attenuated H37Ra strain after autoclaving at 121 °C for 20 min. Mtb-HAg can specifically induce γδ T-cell proliferation in vitro. However, exact composition and protein antigens that are responsible its function currently unknown. Methods extracted Mtb was subjected to LC‒MS mass spectrometry. Twelve identified fractions were...
Abstract Root development is essential for plant survival. The lack of carotenoid biosynthesis in the phytoene desaturase 3 ( pds3 ) mutant results short primary roots (PR) and reduced lateral root (LR) formation. In this study, we show that short-term inhibition PDS by fluridone suppressed PR growth WT, but to a lesser extent auxin mutants. Such an activity increased endogenous indole-3-acetic acid (IAA) levels, promoted signaling, partially complemented deficient mutant, YUCCA 5 7 8 9...