- Attention Deficit Hyperactivity Disorder
- Child and Adolescent Psychosocial and Emotional Development
- Effects and risks of endocrine disrupting chemicals
- Functional Brain Connectivity Studies
- Infant Development and Preterm Care
- Children's Physical and Motor Development
- Health, Environment, Cognitive Aging
- Bipolar Disorder and Treatment
- Neural and Behavioral Psychology Studies
- Maternal Mental Health During Pregnancy and Postpartum
- Birth, Development, and Health
- Autism Spectrum Disorder Research
- Pharmaceutical studies and practices
- Pesticide Exposure and Toxicity
- Thyroid Disorders and Treatments
- Suicide and Self-Harm Studies
- Anesthesia and Neurotoxicity Research
- Education, Healthcare and Sociology Research
- Family and Disability Support Research
- Per- and polyfluoroalkyl substances research
- Psychiatric care and mental health services
- Adolescent and Pediatric Healthcare
- Child and Adolescent Health
- Pregnancy and Medication Impact
- Neonatal Health and Biochemistry
Oslo University Hospital
2015-2024
University of Oslo
1998-2024
Centre for Addiction and Mental Health
2019
Center for Child and Adolescent Mental Health, Eastern and Southern Norway
1997-1998
There is growing concern that phthalate exposures may have an impact on child neurodevelopment. Prenatal exposure to phthalates has been linked with externalizing behaviors and executive functioning defects suggestive of attention-deficit hyperactivity disorder (ADHD) phenotype.We undertook investigation into whether prenatal was associated clinically confirmed ADHD in a population-based nested case-control study the Norwegian Mother Child Cohort (MoBa) between years 2003 2008.Phthalate...
Exposures to environmental phenols and parabens may be harmful, especially in utero. Prior studies have demonstrated high within-person variability of urinary concentrations across pregnancy.We sought measure phenol paraben biomarker for the Norwegian Mother Child Cohort (MoBa) study, assess variability, investigate any possible external or contamination specimens.We collected three spot urine samples at approximately 17, 23, 29 weeks gestation a hospital setting added preservative...
Perfluoroalkyl substances (PFASs) are persistent organic pollutants that suspected to be neurodevelopmental toxicants, but epidemiological evidence on effects of PFAS exposure is inconsistent. We investigated the associations between prenatal PFASs and symptoms attention-deficit/hyperactivity disorder (ADHD) cognitive functioning (language skills, estimated IQ working memory) in preschool children, as well effect modification by child sex.This study included 944 mother-child pairs enrolled a...
The preschool period is an important developmental for the emergence of cognitive self-regulatory skills or executive functions (EF). To date, evidence regarding structure EF in children has supported both unitary and multicomponent models. aim present study was to test factor early as measured by Behavior Rating Inventory Executive Function-Preschool version (BRIEF-P). BRIEF-P consists five subscales three broader indexes, hypothesized tap into different subcomponents EF. Parent ratings...
Abstract Background Self-harm in adolescents is an increasing public health concern and important risk factor for suicide. We aimed to examine how age of self-harm onset was associated with frequency subsequent suicidal non-suicidal (NSSI) episodes, duration may influence the self-harm. Methods Data from 103 recurrent recruited child adolescent psychiatric outpatient clinics were collected through clinical interviews self-reports, analysed negative binomial hurdle models. Results A lower a...
Objective: To study the quality of life in adults aged 50+ with ADHD. Method: An anonymous questionnaire survey was performed on 148 Quality assessed EuroQol and Satisfaction With Life Scale. Age-matched Norwegian Danish population samples served as reference groups. Results: Mean age participants 55.7 years, mean when diagnosed ADHD 50.2 while Adult Self-Report Scale Screener score 15.2. Adults reported significantly reduced health-related satisfaction compared norms. Nonemployment severe...
Human populations, including susceptible subpopulations such as pregnant women and their fetuses, are continuously exposed to phthalates. Phthalates may affect the thyroid hormone system, causing concern for pregnancy health, birth outcomes child development. Few studies have investigated joint effect of phthalates on function in women, although they present a mixture with highly inter-correlated compounds. Additionally, no if key nutrient iodine, modifies these relationships. In this study,...
Background: Early symptoms of attention deficit/hyperactivity disorder (ADHD) and oppositional-defiant (ODD) are associated with deficits in cognitive self-regulatory processes or executive functions (EF)s. However, the hypothesis that neurocognitive underlying two disorders already evident during early preschool years still has limited empirical support. The present study investigated associations between ADHD and/or ODD core EFs, inhibition working memory, a large nonclinical sample 3-year...
Recent research has demonstrated that deficits in basic, self-regulatory processes, or executive function (EF), may be related to symptoms of attention-deficit/hyperactivity disorder (ADHD) already during the preschool period. As majority studies investigating these relations young children have been based primarily on clinically administered tests, it is not clear how early ADHD observations EF an everyday context. The version Behavior Rating Inventory Executive Function (BRIEF-P) was...
Background: Organophosphate esters (OPEs) are ubiquitous chemicals, used as flame retardants and plasticizers. OPE usage has increased over time a substitute for other controlled compounds. This study investigates the impact of prenatal exposure on executive function (EF) in preschoolers. Methods: We selected 340 preschoolers from Norwegian Mother, Father, Child Cohort Study. Diphenyl-phosphate (DPhP), di-n-butyl-phosphate (DnBP), bis(2-butoxyethyl) phosphate (BBOEP),...
Abstract Addressing current challenges in research on disruptive mood dysregulation disorder (DMDD), this study aims to compare executive function children with DMDD, attention-deficit/hyperactivity (ADHD), and oppositional defiant (ODD). We also explore associations between irritability, a key DMDD characteristic, clinical sample regardless of diagnosis. Our include (6–12 years) referred child psychiatric clinics. Measures daily-life (parent-reported questionnaire) performance-based...
Patterns of co-occurrence between ADHD, Oppositional Defiant Disorder (ODD), and Conduct (CD) were examined in a sample non-referred preschool children. ADHD subtypes sex differences also explored.Children aged 3.5 years ( n = 1,048) with high scores on characteristics recruited from the Norwegian Mother Child Cohort Study clinically assessed, including semi-structured psychiatric interview.In children concurrent ODD was present more often than CD (31% vs. 10%), but having gave higher...
Cohort studies often report findings on children with Attention Deficit Hyperactivity Disorder (ADHD) but may be biased by self-selection. The representativeness of cohort needs to investigated determine whether their can generalised the general child population. aim present study was examine ADHD in Norwegian Mother and Child Study (MoBa). population born between January 1, 2000 December 31, 2008 registered hyperkinetic disorders (hereafter ADHD) Patient Registry during years 2008–2013, two...
To investigate adult ADHD symptoms and satisfaction with life, a focus on age sex differences.This study is based parents in the Norwegian Mother Child Cohort Study (MoBa). The Adult Self-Report Scale (ASRS-6) Satisfaction With Life (SWLS) scores were analyzed from 33,210 men 41,983 women young to middle adulthood.Mean ASRS total score was significantly higher men, where 5.1% scored above cutoff, compared 2.9% women. Factor loadings supported two subscales: Inattention (Inatt)...
ObjectiveAlthough early and accurate screening is required for the remediation of attention-deficit/hyperactivity disorder (ADHD), possible gender differences have not been extensively studied. We examined classification accuracy parent preschool teacher version Strengths Difficulties Questionnaire (SDQ) hyperactivity−inattention (HI) subscale in girls boys.MethodThe study was part Norwegian Mother Child Cohort Study (MoBa). Parents teachers rated a total 238 276 boys (mean age 3.5 years)...
To study the efficacy and tolerability of atomoxetine in high-functioning boys with autism spectrum disorders (ASD) comorbid attention deficit/hyperactivity disorder (AD/HD).Fourteen (age 7-17) participated a 10-week open-label study. Atomoxetine doses were 0.5 mg/kg/day week 1 1.2-1.4 weeks 2-10. Changes AD/HD symptoms measured by Rating Scale, global improvements Clinical Global Improvement Scale. Both measures used to assess drug response. Assessments done at baseline 2, 4, 6 10. Teacher...
Anxiety disorders and attention deficit/hyperactivity disorder (ADHD) develop before school age, but little is known about early developmental pathways. Here we test two hypotheses: first, that signs of anxiety ADHD at 18 months predict symptoms age 3½ years; second, emotional dysregulation predicts the outcome co-occurring years. The study was part prospective Norwegian Mother Child Cohort Study (MoBa) Institute Public Health. 628 participants were clinically assessed Questionnaire data...