Denye Ogeh
A5082323973- Genomics and Phylogenetic Studies
- RNA and protein synthesis mechanisms
- Molecular Biology Techniques and Applications
- Bat Biology and Ecology Studies
- Animal Behavior and Reproduction
- Marine Ecology and Invasive Species
- vaccines and immunoinformatics approaches
- Subterranean biodiversity and taxonomy
- Machine Learning in Bioinformatics
- Chromosomal and Genetic Variations
- Mobile Health and mHealth Applications
- CRISPR and Genetic Engineering
- Genetic and phenotypic traits in livestock
- Diabetes Management and Research
- COVID-19 epidemiological studies
- Vaccine Coverage and Hesitancy
- Bioinformatics and Genomic Networks
- Diabetes Management and Education
- interferon and immune responses
- Genetic Mapping and Diversity in Plants and Animals
- Gene expression and cancer classification
- SARS-CoV-2 and COVID-19 Research
- Evolutionary Algorithms and Applications
- RNA modifications and cancer
- Viral Infections and Outbreaks Research
European Bioinformatics Institute
2017-2024
University of Leicester
2016
Covenant University
2016
The Ensembl project has been aggregating, processing, integrating and redistributing genomic datasets since the initial releases of draft human genome, with aim accelerating genomics research through rapid open distribution public data. Large amounts raw data are thus transformed into knowledge, which is made available via a multitude channels, in particular our browser (http://www.ensembl.org). Over time, we have expanded multiple directions. First, resources describe fields genomics, gene...
Ensembl (https://www.ensembl.org) is unique in its flexible infrastructure for access to genomic data and annotation. It has been designed efficiently deliver annotation at scale all eukaryotic life, it also provides deep comprehensive key species. Genomes representing a greater diversity of species are increasingly being sequenced. In response, we have focussed our recent efforts on expediting the new assemblies. Here, report release greatest annual number newly annotated genomes history...
The Ensembl project (https://www.ensembl.org) makes key genomic data sets available to the entire scientific community without restrictions. seeks be a fundamental resource driving progress by creating, maintaining and updating reference genome annotation comparative genomics resources. This year we describe our new expanded gene, variant capabilities, which led 50% increase in number of vertebrate genomes support. We have also doubled human variants added regulatory regions for many mouse...
Ensembl (https://www.ensembl.org) has produced high-quality genomic resources for vertebrates and model organisms more than twenty years. During that time, our resources, services tools have continually evolved in line with both the publicly available genome data downstream research applications utilise platform. In recent years we witnessed a dramatic shift landscape. There been large increase number of reference genomes through global biodiversity initiatives. parallel, there major...
Abstract Ensembl (https://www.ensembl.org) is a freely available genomic resource that has produced high-quality annotations, tools, and services for vertebrates model organisms more than two decades. In recent years, there been dramatic shift in the landscape, with large increase number phylogenetic breadth of reference genomes, alongside major advances pan-genome representations higher species. order to support these efforts accelerate downstream research, continues focus on scaling rapid...
Domestic ducks are raised for meat, eggs and feather down, almost all varieties descended from the Mallard (Anas platyrhynchos). Here, we report chromosome-level high-quality genome assemblies meat laying duck breeds, Mallard. Our new genomic databases contain annotations thousands of protein-coding genes recover a major percentage presumed "missing genes" in birds. We obtain entire sequences C-type lectin (CTL) family members that regulate eggshell biomineralization. population comparative...
Abstract Background The Australian black swan ( Cygnus atratus ) is an iconic species with contrasting plumage to that of the closely related northern hemisphere white swans. relative geographic isolation may have resulted in a limited immune repertoire and increased susceptibility infectious diseases, notably diseases from which Australia has been largely shielded. Unlike mallard ducks mute olor ), extremely sensitive highly pathogenic avian influenza. Understanding this impaired by absence...
Abstract The ability of organisms to adapt sudden extreme environmental changes produces some the most drastic examples rapid phenotypic evolution. Mexican Tetra, Astyanax mexicanus, is abundant in surface waters northeastern Mexico, but repeated colonizations cave environments have resulted independent evolution troglomorphic phenotypes several populations. Here, we present three chromosome-scale assemblies this species, for one and two populations, enabling first whole-genome comparisons...
Abstract The COVID-19 pandemic has seen unprecedented use of SARS-CoV-2 genome sequencing for epidemiological tracking and identification emerging variants. Understanding the potential impact these variants on infectivity virus efficacy therapeutics vaccines become a cornerstone fight against disease. To support maximal genomic information research, we launched Ensembl browser; first to be encompassed within platform. This resource incorporates new gene set, multiple variant sets, annotation...
Abstract The ability of organisms to adapt sudden extreme environmental changes produces some the most drastic examples rapid phenotypic evolution. Mexican Tetra, Astyanax mexicanus , is abundant in surface waters northeastern Mexico, but repeated colonizations cave environments have resulted independent evolution troglomorphic phenotypes several populations. Here, we present three chromosome-scale assemblies this species, for one and two populations, enabling first whole-genome comparisons...
Computational and mathematical models play important roles in proffering solutions to infectious diseases.Economic development human health Africa continues decline as a result of the menace diseases.No doubt, can be haven economic stability with healthy population but not until this challenge is overcome.The significance computational modelling control diseases cannot overemphasized.Hence, an extensive study on impact timely study.Specifically, scope our focused four life-threatening common...
Abstract Motivation The advent of Next Generation Sequencing (NGS) has led to the generation enormous volumes short read sequence data, cheaply and in reasonable time scales. Nevertheless, quality genome assemblies generated using NGS technologies been greatly affected, compared those Sanger DNA sequencing. This is largely due inability data scaffold repetitive structures, creating gaps, inversions rearrangements resulting that are, at best, draft forms. Third single-molecule sequencing...
ABSTRACT The Australian black swan ( Cygnus atratus ) is an iconic species with contrasting plumage to that of the closely related Northern Hemisphere white swans. relative geographic isolation may have resulted in a limited immune repertoire and increased susceptibility infectious disease, notably diseases from which Australia has been largely shielded. Indeed, unlike Mallard ducks mute olor ), extremely sensitive severe highly pathogenic avian influenza (HPAI). Understanding this impaired...
ABSTRACT The COVID-19 pandemic has seen unprecedented use of SARS-CoV-2 genome sequencing for epidemiological tracking and identification emerging variants. Understanding the potential impact these variants on infectivity virus efficacy therapeutics vaccines become a cornerstone fight against disease. To support maximal genomic information research, we launched Ensembl browser, incorporating new gene set, multiple variant sets (including novel variation calls), annotation from several...