A5014257109- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- DNA and Nucleic Acid Chemistry
- RNA and protein synthesis mechanisms
- Protein Structure and Dynamics
- Enzyme Structure and Function
- Bacteriophages and microbial interactions
- Microbial Metabolic Engineering and Bioproduction
- RNA modifications and cancer
- Bioinformatics and Genomic Networks
- BRCA gene mutations in cancer
- Organometallic Complex Synthesis and Catalysis
- RNA Research and Splicing
- Genomics and Phylogenetic Studies
- Crystallography and molecular interactions
- Genetics, Bioinformatics, and Biomedical Research
- Advanced biosensing and bioanalysis techniques
- CRISPR and Genetic Engineering
- Nutrition, Genetics, and Disease
- Genomics and Rare Diseases
- Meat and Animal Product Quality
- DNA Repair Mechanisms
- Enzyme Production and Characterization
- Monoclonal and Polyclonal Antibodies Research
- Animal Genetics and Reproduction
UNSW Sydney
1973-2025
Heriot-Watt University
2019
Wellcome Trust
2003-2017
European Bioinformatics Institute
2003-2017
Universität Bayern
2017
National Human Genome Research Institute
1990-2015
Cold Spring Harbor Laboratory
1977-2015
University of Auckland
1966-2015
University of Cambridge
1954-2008
Birkbeck, University of London
2003-2007
ProFunc ( http://www.ebi.ac.uk/thornton-srv/databases/ProFunc ) is a web server for predicting the likely function of proteins whose 3D structure known but not. Users submit coordinates their to in PDB format. makes use both existing and novel methods analyse protein's sequence identifying functional motifs or close relationships functionally characterized proteins. A summary analyses provides an at-a-glance view what each different has found. More detailed results are available on separate...
This paper describes a possible structure for the paracrystalline form of sodium salt deoxyribonucleic acid. The consists two DNA chains wound helically round common axis, and held together by hydrogen bonds between specific pairs bases. assumptions made in deriving are described, co-ordinates given principal atoms. crystalline is discussed briefly.
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We can now have considerable confidence that the broad features of protein synthesis are understood. The involvement RNA is very much more complicated than was imagined in 1953. There not one functional RNA. Instead, demands ordered interaction three classes RNA-ribosomal, soluble, and messenger. Many important questions, however, remain unanswered. For instance, there no theoretical framework for ribosomal subunits, nor matter, do we understand significance Most satisfying realization all...
We have reprinted Watson and Crick's original paper from the 25 April 1953 issue of Nature (with permission publisher). It repays careful reading for its scientific content; spare, preci...
Alternative premessenger RNA splicing enables genes to generate more than one gene product. Splicing events that occur within protein coding regions have the potential alter biological function of expressed and even create new functions. has been suggested as explanation for discrepancy between number human functional complexity. Here, we carry out a detailed study alternatively spliced products annotated in ENCODE pilot project. We find alternative is frequent commonly suggested,...
Integrating the tools of genomics and neural science is needed to reveal causes neuropsychiatric illnesses suggest new strategies for treatment prevention.