A5068386780- Hepatitis Viruses Studies and Epidemiology
- Viral gastroenteritis research and epidemiology
- Bacillus and Francisella bacterial research
- Child Nutrition and Water Access
- Global Maternal and Child Health
- Viral Infections and Outbreaks Research
- Pediatric health and respiratory diseases
- Congenital Anomalies and Fetal Surgery
- Animal Virus Infections Studies
- Influenza Virus Research Studies
- Biotechnology and Related Fields
- Pneumonia and Respiratory Infections
- Animal testing and alternatives
- Tuberculosis Research and Epidemiology
- COVID-19 epidemiological studies
- Streptococcal Infections and Treatments
- Respiratory viral infections research
- Mosquito-borne diseases and control
- Biomedical and Engineering Education
- Infective Endocarditis Diagnosis and Management
- Bacterial Identification and Susceptibility Testing
- Poverty, Education, and Child Welfare
- Zoonotic diseases and public health
- Pneumocystis jirovecii pneumonia detection and treatment
- Chemical Safety and Risk Management
Kenya Medical Research Institute
2018-2025
Jomo Kenyatta University of Agriculture and Technology
2021
<sec><title>BACKGROUND</title>The loop-mediated isothermal amplification for TB (TB-LAMP) assay is more cost-effective and accessible than the Xpert ® MTB/RIF assay. This study aimed to evaluate diagnostic performance of TB-LAMP in individuals with without HIV infection.</sec><sec><title>METHODS</title>Patients aged ≥15 years presenting symptoms were included study. The was performed alongside routine methods, including smear microscopy,...
Abstract Background Rotavirus, norovirus, adenovirus (type 40/41) and astrovirus are the most significant viral etiological agents of acute gastroenteritis in young children globally. Kenya introduced rotavirus vaccine into her National Immunization Program July 2014, which has led to a decline prevalence rotavirus. We sought assess impact vaccination on epidemiological trends other diarrhea-associated enteric viruses across different regions Kenya. Methodology Using conventional multiplex...
Abstract Aim This study aimed to develop a multiplex PCR assay for simultaneous detection of major Gram-negative etiologies septicemia and evaluate its performance. Methods Multiplex (mPCR) assays were developed targeting 11 bacterial strains. Species-specific primers confirmed using known clinical isolates standard Gradient was performed on each primer against target gene determine optimal amplification condition. The minimum detectable DNA concentration the two evaluated by adjusting 100...
The NUITM-KEMRI biosafety training program was developed for capacity building of new level three (BSL-3) laboratory users. comprehensively covers and biosecurity theory practice. Its curriculum is based on the WHO guidelines, local standards, ongoing research activities in facility, also taking into consideration emerging public health issues. program's approach enhances participant's knowledge builds their skills through hands-on practice sessions mentorship training. Subsequently,...
Abstract Objectives We assessed the impact of water, hygiene and sanitation (WASH), maternal, new‐born child health (MNCH), nutrition early childhood development (ECD) on diarrhoea microbial quality water in a resource‐constrained rural setting Kenya. Methods Through controlled intervention study, we tested faecal samples collected from both control sites before after interventions using microbiological, immunological molecular assays to determine prevalence diarrhoeagenic agents water. Data...
When properly used and adequately maintained, a biological safety cabinet (BSC) provides protection to the laboratory worker, products, environment. Knowledge about proper use of BSC is therefore important. This study evaluated usage knowledge practices effect prior experience on training outcomes. Thirteen participants randomly selected from research centers were through structured questionnaire covering biosafety considerations involved in using as per World Health Organization’s...
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Water, sanitation and hygiene (WASH) child health interventions are proven simple cost-effective strategies for preventing diarrhea minimizing excess mortality. Individually, they able to prevent though sub-optimally, their effectiveness when combined may be higher. This study examined the effect of integrated WASH maternal (MCH) on prevalence diarrhea, in a resource-limited setting Kenya.
Objective: To examine occurrence of Acute Respiratory tract Infections (ARIs) and determine factors associated with ARIs among children under five years attending Kinango Sub-County Hospital. Methods: A cross-sectional survey was conducted mother-child aged between 0-59 month’s pairs outpatient care. Participants were recruited using systematic sampling method. Data collected an interviewer-administered structured questionnaire. Descriptive statistics used to summarize child, parental...
Abstract Background Influenza viruses are an important cause of respiratory infections across all age groups. Information on occurrence and magnitude influenza virus in different populations Kenya however remains scanty, compromising estimation disease burden. This study examined infection urban high-income setting Nairobi to establish its prevalence activity viruses, evaluated diagnostic performance a rapid test. Methodology A cross-sectional hospital-based was conducted six private health...