Jenna R. Osterlund Oltmanns

ORCID: 0000-0003-4461-6205
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About
Contact & Profiles
Research Areas
  • Memory and Neural Mechanisms
  • Spaceflight effects on biology
  • Neurogenesis and neuroplasticity mechanisms
  • Circadian rhythm and melatonin
  • Zebrafish Biomedical Research Applications
  • Anesthesia and Neurotoxicity Research
  • Olfactory and Sensory Function Studies
  • Motor Control and Adaptation
  • Birth, Development, and Health
  • COVID-19 Pandemic Impacts
  • COVID-19 and Mental Health
  • Prenatal Substance Exposure Effects
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Higher Education Research Studies
  • RNA regulation and disease
  • Neural dynamics and brain function
  • Stress Responses and Cortisol
  • Transcranial Magnetic Stimulation Studies
  • Sleep and Wakefulness Research
  • RNA and protein synthesis mechanisms
  • RNA Research and Splicing
  • Neuroscience and Neuropharmacology Research
  • Fatty Acid Research and Health
  • Vestibular and auditory disorders
  • Muscle activation and electromyography studies

Northern Illinois University
2020-2024

Genetic mutations that disrupt open reading frames and cause translation termination are frequent causes of human disease difficult to treat due protein truncation mRNA degradation by nonsense-mediated decay, leaving few options for traditional drug targeting. Splice-switching antisense oligonucleotides offer a potential therapeutic solution diseases caused disrupted inducing exon skipping correct the frame. We have recently reported on an exon-skipping oligonucleotide has effect in mouse...

10.1016/j.omtn.2023.05.025 article EN cc-by-nc-nd Molecular Therapy — Nucleic Acids 2023-06-03

Abstract Background Prenatal alcohol exposure (PAE) can produce deficits in a wide range of cognitive functions but is especially detrimental to behaviors requiring accurate spatial information processing. In open field environments, behavior organized such that animals establish “home bases” marked by long stops focused around one location. Progressions away from the home base are circuitous and slow, while progressions directed toward non‐circuitous fast. The impact PAE on organization has...

10.1111/acer.14813 article EN Alcoholism Clinical and Experimental Research 2022-03-22

The proposed mission to Mars will expose astronauts space radiation that is known adversely affect cognition and tasks rely on fine sensorimotor function. Space has also been shown the microglial neurogenic responses in central nervous system (CNS). We recently reported a low dose of 5 cGy 600 MeV/n 28Si results impaired skilled motor behavior adult rats. Since these at least part proper functioning striatum, we examined striatal cells same subjects. Using morphometric analysis, found...

10.1667/rade-21-00021.1 article EN Radiation Research 2022-04-04

ABSTRACTThe shift to online learning due the COVID-19 pandemic exacerbated existing inequalities and highlighted failures of U.S. higher education institutions serve their students' needs. The purpose this exploratory quantitative survey study was examine differences in perceptions academic financial challenges encountered during pandemic. Results by generation status, gender, intersections. Insight into these sub-populations can shed light on ways reorganize educational structures provide...

10.1080/26906015.2023.2253834 article EN Journal of First-generation Student Success 2023-09-02
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