A5000232207- Acute Kidney Injury Research
- Nitric Oxide and Endothelin Effects
- Cardiac electrophysiology and arrhythmias
- Cardiovascular Function and Risk Factors
- Cardiac Arrest and Resuscitation
- Coenzyme Q10 studies and effects
- Medical Imaging and Pathology Studies
- Fibroblast Growth Factor Research
- Signaling Pathways in Disease
- Cardiac Ischemia and Reperfusion
- Parathyroid Disorders and Treatments
- Vitamin K Research Studies
- Vitamin C and Antioxidants Research
Universidade Federal do ABC
2019-2021
In kidney disease (KD), several factors released into the bloodstream can induce a series of changes in heart, leading to wide variety clinical situations called cardiorenal syndrome (CRS). Reactive oxygen species (ROS) play an important role signaling and progression systemic inflammatory conditions, as observed KD. The aim present study was characterize redox balance renal ischemia/reperfusion-induced cardiac remodeling. C57BL/6 male mice were subjected occlusion left pedicle, unilateral,...
Cardiorenal syndrome (CRS) is a pathological link between the kidneys and heart, in which an insult kidney or heart leads other organ to incur damage. CRS classified into five subtypes, type 3 (CRS3) characterized by acute injury as precursor subsequent cardiovascular changes. Mitochondrial dysfunction oxidative nitrosative stress have been reported pathophysiology of CRS3. It known that vitamin C, antioxidant, has proven protective capacity for cardiac, renal, vascular endothelial tissues....
Introduction In diseases that generate an inflammatory situation, such as cardiorenal syndrome, different clinical conditions promote cardiac and renal dysfunction. There are type 3 4 which characterized by insults subject the heart to dysfunctions; Among changes injury can lead, we mention modulation in Klotho levels, a gene is negatively regulated fibroblast growth factor 23 (FGF23). The objective of this study evaluate participation axis hypertrophy induced ischemia Methods C57BL/6 male...
Introduction It is known that kidney injury by ischemia/reperfusion (I/R) leads to cardiac hypertrophy mediated immune system. Besides, the Nitric Oxide (NO) can be produced Synthase (NOS) plays a key role in cell signaling including heart and kidney. However, of NO NOS, pathophysiological caused renal I/R has yet clarified. In this study, we begin investigate NOS expression levels after protocol. Methods C57BL/6 male mice were subjected surgical occlusion left pedicle for 60 min followed...