A5041195710- Endometriosis Research and Treatment
- Reproductive System and Pregnancy
- Reproductive Biology and Fertility
- Menopause: Health Impacts and Treatments
- Ovarian function and disorders
- Estrogen and related hormone effects
- Uterine Myomas and Treatments
- Sperm and Testicular Function
- Hormonal and reproductive studies
- Bone health and osteoporosis research
- Gynecological conditions and treatments
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Bone health and treatments
- Assisted Reproductive Technology and Twin Pregnancy
- Ovarian cancer diagnosis and treatment
- Endometrial and Cervical Cancer Treatments
- Phytoestrogen effects and research
- Intestinal and Peritoneal Adhesions
- Regulation of Appetite and Obesity
- Urinary and Genital Oncology Studies
- Cancer Risks and Factors
- Cultural and Sociopolitical Studies
- Pelvic floor disorders treatments
- Sex and Gender in Healthcare
- Bone Metabolism and Diseases
Istanbul University-Cerrahpaşa
2008-2025
Bridgeport Hospital
2025
Istanbul Medipol University
2025
Istanbul University
2006-2019
Aristotle University of Thessaloniki
2017
Carol Davila University of Medicine and Pharmacy
2017
National and Kapodistrian University of Athens
2017
Yale University
1998-2003
University of Szeged
1999
New Haven Public Schools
1998
Proliferation of endometrium is dependent on sex steroid hormones, but specific growth factors are likely to play an important role in regulating this process. A number cytokines and synthesized the response hormones act regulate endometrial function. Endometrial cells produce interleukin-8 (IL-8) both vivo vitro. We hypothesized that IL-8, a neutrophil chemoattractant/activating factor potent angiogenic agent has been shown stimulate other cell types, may directly proliferation cells. first...
We have previously shown that interleukin-8 (IL-8), a cytokine with neutrophil chemotactic/activating and T cell chemotactic activity, is produced by human endometrial stromal glandular cells in culture. The present study investigated the temporal spatial expression of IL-8 messenger ribonucleic acid (mRNA) protein endometrium. Endometrial tissue (n = 52) was obtained from uteri after hysterectomy conducted for reasons other than disease or biopsies. day menstrual cycle established women's...
There is a cyclicity in the number of endometrial macrophages that most likely secondary to changes steroid hormone levels. One cytokine controls macrophage migration monocyte chemotactic protein-1 (MCP-1). In endometrium, highest levels MCP-1 are detected perimenstrually, when estrogen low; however, high (around time ovulation), lowest. We hypothesized sex steroids may be involved regulation by regulating expression. investigated expression human stromal cells estradiol 17beta (E2) and...
As part of our studies on sperm maturity and function, we examined the head, midpiece tail human spermatozoa using computerized morphometry in order to determine which regions reflect differences between mature diminished cellular maturity. We studied 20 men, who were divided into two groups based their lower (LCKM: 14.6 +/- 7.0%, n = 8) higher creatine kinase (CK-M) isoform ratios (HCKM: 48.0 4.3%, 12) initial semen. Using a sequential centrifugation method relies density immature with...
To whom correspondence should be addressed Invasion of the corpus luteum by macrophages is a characteristic luteal regression.Monocyte chemotactic protein-1 (MCP-1), chemokine that recruits macrophages, expressed in rat where it increases amount during luteolysis.In this study we examined temporal and spatial expression MCP-1 changes macrophage concentration human luteum.Corpora lutea (n ⍧ 39) were grouped according to menstrual cycle phase immunohistochemistry for Northern blot mRNA.We...
To investigate the possible ability of homocysteine (Hcy) levels in embryo culture media for estimating better invitro fertilization outcomes endometriosis patients. Nineteen women with who were admitted to Cerrahpaşa Medical Faculty, Department Obstetrics and Gynecology, Infertility Outpatient Clinic diagnosis infertility included study. The results intracytoplasmic sperm injection treatments recorded Hcy evaluated. compared those control patients without endometriosis, had previously been...
This study aimed to evaluate the prevalence and severity of menopausal symptoms among perimenopausal women in a rural area southeastern Turkey their association with sleep quality, depression sociodemographic lifestyle-related factors. cross-sectional included 122 aged 40-55 years residing Turkey. Participants completed Beck Depression Inventory (BDI), Menopause Rating Scale (MRS) Pittsburgh Sleep Quality Index (PSQI), alongside demographic data collection. The median age was 46 (43-49...
The human fallopian tube is a dynamic structure that undergoes cyclic variation in its functional epithelium. This epithelium contains both secretory and ciliated cells. mechanisms regulating the growth function of tubal are not fully understood. Interleukin-8 (IL-8) one potential local regulatory factor. We therefore characterized IL-8 system, which includes IL-8, receptors A B, degradative enzyme aminopeptidase N, by immunohistochemistry. Immunohistochemistry was performed on isthmic,...