A5045610877- Advanced Radiotherapy Techniques
- Lung Cancer Diagnosis and Treatment
- Management of metastatic bone disease
- Prostate Cancer Treatment and Research
- Prostate Cancer Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Gastric Cancer Management and Outcomes
- Esophageal Cancer Research and Treatment
- Lung Cancer Treatments and Mutations
- Hepatocellular Carcinoma Treatment and Prognosis
- Head and Neck Cancer Studies
- Advances in Oncology and Radiotherapy
- Esophageal and GI Pathology
- Medical Imaging Techniques and Applications
- Colorectal Cancer Treatments and Studies
- Cancer Diagnosis and Treatment
- Glioma Diagnosis and Treatment
- Radiation Therapy and Dosimetry
- Spine and Intervertebral Disc Pathology
- Brain Metastases and Treatment
- Colorectal Cancer Surgical Treatments
- Radiopharmaceutical Chemistry and Applications
- Effects of Radiation Exposure
- Colorectal and Anal Carcinomas
- Radiation Dose and Imaging
Trinity College Dublin
2022-2025
Inserm
2025
Centre de recherche en Epidémiologie et Santé des Populations
2025
Université Paris-Saclay
2025
Beacon College
2024
St. Luke's Hospital
2010-2023
Cancer Trials Ireland
2014-2023
St. James's Hospital
2019-2020
Institut Bergonié
2016
St. Luke's-Roosevelt Hospital Center
2008-2012
In 2007 ESTRO proposed a revision and harmonisation of the core curricula for radiation oncologists, medical physicists RTTs to encourage harmonised education programmes professional disciplines, facilitate mobility between EU member states, reflect rapid development professions secure best evidence-based across Europe.Working parties each curriculum were established included broad representation with geographic spread different experience from Educational Committee, local representatives...
PURPOSE The optimal neoadjuvant treatment for resectable carcinoma of the thoracic esophagus (TE) or gastroesophageal junction (GEJ) remains a matter debate. We performed an individual participant data (IPD) network meta-analysis (NMA) randomized controlled trials (RCTs) to study effect chemotherapy chemoradiotherapy, with focus on tumor location and histology subgroups. PATIENTS AND METHODS All, published unpublished, RCTs closed accrual before December 31, 2015 having compared at least two...
Therapeutic exposure to ionising radiation reveals inter-individual variations in normal tissue responses. To examine whether a defect DNA repair capacity might be involved such hypersensitive phenotypes, we analysed, using the alkaline comet assay, response as function of time vitro irradiation at 5 Gy lymphocytes from 17 breast cancer and 9 Hodgkin's disease patients who developed severe reactions radiotherapy comparison with 22 "average" 24 healthy donors. A difference between...
4512 Background: Optimal management of operable localised oesophageal carcinoma remains to be determined. The debate is fuelled by some positive individual trials showing a benefit preoperative chemotherapy (CT+S) or chemo-radiotherapy (CRT+S) over surgery alone (S). Our group has initiated an patient data-based meta-analysis quantify the potential CT+S S. Methods: methodology used for trial identification and data analysis been previously reported. primary endpoint was overall survival...
Background: The optimal primary external beam radiation therapy (EBRT) schedule for malignant epidural spinal cord compression (MSCC) remains to be determined. ICORG 05-03 trial assessed if a 10 Gy single fraction was not inferior one with 20 Gray (Gy) in five daily fractions, terms of functional motor outcome, the treatment MSCC patients proceeding surgical decompression. This article reports on two secondary endpoints, Quality life (QoL), according European Organization Research and...
The optimal EBRT schedule for MSCC is undetermined. Our aim was to determine whether a single fraction (SF) non-inferior five daily fractions (5Fx), functional motor outcome.Patients not proceeding with surgical decompression in this multicentre non-inferiority, Phase 3 trial were randomised 10 Gy/SF or 20 Gy/5Fx. A change mobility from baseline 5 weeks each patient, evaluated by Modified Tomita score: 1 = 'Walk unaided', 2 'With walking aid' and 'Bed-bound'. margin used establish...