- Radiomics and Machine Learning in Medical Imaging
- MRI in cancer diagnosis
- Prostate Cancer Diagnosis and Treatment
- Medical Imaging Techniques and Applications
- Ovarian cancer diagnosis and treatment
- Urologic and reproductive health conditions
- Head and Neck Cancer Studies
- Prostate Cancer Treatment and Research
- Bone and Joint Diseases
- Medical Imaging and Pathology Studies
- Colorectal and Anal Carcinomas
- Cancer Diagnosis and Treatment
- Advanced Neuroimaging Techniques and Applications
- Lung Cancer Diagnosis and Treatment
- Colorectal Cancer Surgical Treatments
- Music Therapy and Health
- Growth Hormone and Insulin-like Growth Factors
- Mental Health via Writing
- Sarcoidosis and Beryllium Toxicity Research
- Machine Learning in Bioinformatics
- Osteomyelitis and Bone Disorders Research
- Intraperitoneal and Appendiceal Malignancies
- Spectroscopy Techniques in Biomedical and Chemical Research
- Anorectal Disease Treatments and Outcomes
- Cancer Immunotherapy and Biomarkers
Christian Medical College, Vellore
2025
Imperial College London
2015-2024
Imperial College Healthcare NHS Trust
2014-2024
Mount Vernon Cancer Centre
2024
Charing Cross Hospital
2019-2024
Creative Commons
2023
University College London
2023
University College Hospital
2023
Guy's and St Thomas' NHS Foundation Trust
2023
King's College London
2023
Purpose . Retrospectively evaluate the density of cerebral venous sinuses in nonenhanced head CTs (NCTs) and correlate these with presence or absence a sinus thrombus (CVST). Materials Methods. Institutional review board approval was obtained informed consent waived prior to commencing this retrospective study. Over two-year period, all CT venograms (CTVs) performed at our institution were retrieved preceding/subsequent NCTs evaluated. Hounsfield Units (HUs) when present as well that normal...
Background. Contrast-induced nephropathy (CIN) is a recognised complication of intravascular administration iodinated contrast media (ICM). Previous studies suggest higher incidence in the elderly, but no large study has assessed this to date. We set out assess changes creatinine elderly inpatients following computed tomography (CT) examination and compare those who received intravenous did not. Methods. Using Radiology Information System two teaching hospitals, over age seventy had CT...
Osteoradionecrosis (ORN) is one of the complications after high-dose-radiotherapy due to damage normal bony tissues. ORN may occur years radiotherapy and clinical manifestation mimic disease recurrence. This study aimed determine incidence shown in 18F-FDG-PET-CT post-radiotherapy head neck cancer (HNC) patients.
Aims18F-FDG-PET-CT plays an important role in the management of head and neck cancers (HNC).In particular, presence/absence local osseous invasion is factor T-staging determining treatment options.This study aimed to determine accuracy PET-CT prediction by cancers.
Objectives Whole-body magnetic resonance imaging (WB-MRI) has been demonstrated to be efficient and cost-effective for cancer staging. The study aim was develop a machine learning (ML) algorithm improve radiologists' sensitivity specificity metastasis detection reduce reading times. Materials Methods A retrospective analysis of 438 prospectively collected WB-MRI scans from multicenter Streamline studies (February 2013–September 2016) undertaken. Disease sites were manually labeled using...
Radical chemoradiotherapy represents the gold standard for locally advanced cervical cancer. However, despite significant progress in improving local tumour control, distant relapse continues to impact overall survival. The development of predictive and prognostic biomarkers is consequently important risk-stratify patients identify populations at higher risk poorer treatment response survival outcomes. Exploratory study using Magnetic resonance Prognostic Imaging markers Radiotherapy In...
18F-FDG PET-CT plays a significant role in the management of head and neck (H&N) malignancies. There have been recent suggestions that half-body (above diaphragm) may be sufficient for H&N cancer patients. This study aims to determine if is safe practice option, or should we stick whole-body PET-CT.
Purpose18F-FDG PET-CT plays an important role in the management of fever unknown origin.FUO is defined as "body core temperature <38.3°C on several occasions lasting for <3 weeks but no cause found despite routine clinical investigations <1 week hospital".Malignancy FUO, and aim this study to demonstrate prevalence malignancy a FUO demonstrated PET-CT. MethodsA total 231 patients with were prospectively studied using after negative conventional investigations.Final diagnosis was based...
Learning objectives1. To understand the role of FDG PET/CT imaging in multimodality investigation gynecological and genitourinary cancers.2. describe mechanism action technical pitfalls FDG-PET/CT.3. highlight key features physiological non-physiological uptake show how this is essential for interpretation FDG-PET/CT studies.4. to review pathophysiological mechanisms leading potentially false-positive false-negative assessments.
Learning objectivesTo be familiar with the diffusion tensor sequence acquisition used to delineate tracts of prostatic neurovascular bundles.To understand method for seeding and identifying displaying anatomy surgical planning.To potential imaging interpretation pitfalls. Content organisationDiffusion (DTI) may tractography peri-prostatic bundles (NVBs).We will describe MR technique that demonstrate NVB's.The illustrated examples in healthy volunteers cases prostate cancer.Correlation...
Aim18F-FDG-PET-CT plays an important role in oncology staging.While the presence of multiple FDG-avid lesions on PET-CT context known malignancy is generally considered metastases, exact significance solitary FDG-avid-lesions remains unknown.This study was undertaken to evaluate bony patients. MethodsRetrospective review 15,645 studies performed.Further evaluation carried out by conventional imaging, follow-up and biopsy studies.Spontaneous resolution subsequent without a change therapy...
Results SLR was diagnosed in 8/308 (2.6%) HNC patients. Of which 3 had mediastinal nodal uptake only, 2 bilateral hilar only and both uptake. All the 8 patients primary deep cervical lymphadenopathy but no distant metastases, hence misinterpretation of would have upstaged as M1 (metastasis positive). 4 cases were identified on scan for restaging suspected recurrence, tumour staging. The mean SUVmax 6.9 (range 2.4-9.6), size 1.6cm short axis 0.6-2.4cm), with significant difference compared to...
Initial results of a prostate cancer study investigating whether multiparametric MRI (MP-MRI), involving diffusion-weighted (DW) and dynamic contrast-enhanced (DCE) MRI, can predict or assess tumour response to radiotherapy (RT) potentially support adaptive for high-risk patients. Adaptive is treatment technique utilised minimise radiation related toxicity. For some cancers it possible adapt according physical changes that occur during treatment. This not appropriate since observable are...
Objective To compare the clinical validity and utility of Likert assessment Prostate Imaging Reporting Data System (PI‐RADS) v2 in detection clinically significant insignificant prostate cancer. Patients Methods A total 489 pre‐biopsy multiparametric magnetic resonance imaging (mpMRI) scans consecutive patients were subject to prospective paired reporting using both PI‐RADS by expert uro‐radiologists. offered biopsy for any or score ≥4 a 3 with PSA density ≥0.12 ng/mL/mL. Utility was...