A5100730306- Carbon and Quantum Dots Applications
- Advanced biosensing and bioanalysis techniques
- Nanocluster Synthesis and Applications
- Molecular Sensors and Ion Detection
- Luminescence and Fluorescent Materials
- Pharmacological Effects of Natural Compounds
- Electrochemical sensors and biosensors
- RNA Interference and Gene Delivery
- Organic Electronics and Photovoltaics
- Advanced Photocatalysis Techniques
- Traditional Chinese Medicine Analysis
- Phytochemistry and Biological Activities
- Graphene and Nanomaterials Applications
- Conducting polymers and applications
- Advanced Memory and Neural Computing
- Neuroscience and Neural Engineering
- Sulfur Compounds in Biology
- Flavonoids in Medical Research
- Biosensors and Analytical Detection
- MicroRNA in disease regulation
- Gas Sensing Nanomaterials and Sensors
- Advanced Sensor and Energy Harvesting Materials
- Antibiotics Pharmacokinetics and Efficacy
- Protein Interaction Studies and Fluorescence Analysis
- ZnO doping and properties
Zhengzhou University
2011-2024
Chinese Academy of Sciences
2018
Institute of Chemistry
2018
University of Chinese Academy of Sciences
2018
Beijing National Laboratory for Molecular Sciences
2018
Human eyes undertake the majority of information assimilation for learning and memory. Transduction color intensity incident light into neural signals is main process visual perception. Besides light-sensitive elements that function as rods cones, artificial retinal systems require neuromorphic devices to transform stimuli post-synaptic signals. In terms plasticity timescale, synapses with short-term (STP) long-term potentiation (LTP) represent foundation experience acquisition memory...
Abstract Mitochondria play a significant role in many cellular processes. Precise long‐term tracking of mitochondrial status and behavior is very important for regulating cell fate treating diseases. However, developing probes with photostability, capability, tunable long‐wavelength fluorescence has been challenge targeting. Carbon dots (CDs) as new fluorescent nanomaterials low toxicity high stability show increasing advantages bioimaging. Herein, the mitochondria CDs (MitoTCD) intrinsic...
Carbon dots (CDs) are emerging as powerful tools for biosensing and bioimaging because of their intrinsic properties such abundant precursors, facile synthesis, high biocompatibility, low cost, particularly robust tunability stability. In this work, a new type CDs was prepared from m-phenylenediamine folic acid by hydrothermal method. Interestingly, the as-prepared show blue emission in non-hydrogen-bonding solution, whereas green hydrogen-bonding solution. Based on phenomenon, novel...
Carbon dots (CDs) have been widely studied for their excellent properties. However, most of the prepared CDs only show strong emission in blue to green region, which greatly limits application biomedical field. In this report, a new design strategy long-wavelength was reported. The orange phenyl-CDs with good optical properties and biocompatibility were successfully by changing substituted group o-phenylenediamine main band far-red region. With increase polarity, wavelength red-shifts...
Abstract Wound healing is an essential and complex biological process. Research into its mechanism factors that influence effectiveness has led to better treatments. Changes in the microenvironment are demonstrated affect wound healing. Cell polarity a significant microenvironment‐related parameter associated with many physiological pathological activities. However, dynamic changes during have not been investigated. Monitoring cell may open up new avenue for developing Here, method developed...
Abstract Targeted fluorescence probes for imaging and differentiation of hepatocellular carcinoma (HCC) are highly desirable from its scientific research clinical applications. However, most the current targeted focus on variation intracellular microenvironment caused by cancerization hepatocyte, which causes a intensity alteration but fails to produce spatial due lack robust parameters further improving accuracy. Herein, study develops new fluorescent carbon dot (CTF‐CDs) that can target...
An accelerated DNAzyme-based fluorescent nanoprobe was developed for rapid and highly sensitive detection of microRNA in live cells.
Intrinsic lysosomal targeting carbon dots were synthesized with ultrastability for long-term lysosome imaging of living cells and drug-induced apoptotic cells.
We develop an "acceptor dimerization" strategy by a bis-diketopyrrolopyrrole (2DPP) for ambipolar organic semiconductor. Copolymers of 2DPP and benzothiadiazole (BTz) derivatives, P2DPP-BTz P2DPP-2FBTz, are designed synthesized. Both the polymers exhibit narrow optical bandgaps ca. 1.30 eV. The strong electron-withdrawing property results in low-lying lowest unoccupied molecular orbital (LUMO) energy levels polymers, improving electron mobilities. 2D grazing incident X-ray diffraction atomic...
Ferroptosis triggered by an iron-dependent accumulation of lipid reactive oxygen species (ROS) has drawn widespread attention. Directly visualizing the dynamic structures nucleic acids during ferroptosis cells is great importance considering their vital roles in numerous biological functions. However, direct imaging remains challenging, largely due to extremely high concentrations ROS generated ferroptosis, which can affect acid targeted fluorescent probes. To overcome this challenge,...
Monitoring cell viability plays a vital role in fundamental aspects of pathology, medicine, and biology. Mitochondria the nucleolus are involved regulating many biological processes, such as mitochondrial autophagy, apoptosis, growth. Thus, exploring variational reflecting with mitochondria is very significant highly required. Herein, this work, kind fluorescent carbon dots (CDs) capable shuttling between was synthesized through simple microwave-assisted strategy utilized for situ...
Mitochondria are the powerhouse of cell, which maintain metabolism living cells. Mitochondrial membrane potential (MMP) is key parameter mitochondria and represents cellular activity. The programmable MMP transformations, i.e., normal, decrease, vanishing, indicative healthy/damaged/dead states. Therefore, methods for monitoring great importance. In this work, carbon dots responsive to mitochondrial (MMP-CDs) prepared by a simple microwave method. intracellular distribution MMP-CDs dependent...