A5085168339- Catalytic C–H Functionalization Methods
- Sulfur-Based Synthesis Techniques
- Chemical Synthesis and Reactions
- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Catalytic Cross-Coupling Reactions
- Radical Photochemical Reactions
- Synthesis and Catalytic Reactions
- Asymmetric Hydrogenation and Catalysis
- Chemical Synthesis and Analysis
- Oxidative Organic Chemistry Reactions
- Organoboron and organosilicon chemistry
- Quinazolinone synthesis and applications
- Luminescence and Fluorescent Materials
- Phenothiazines and Benzothiazines Synthesis and Activities
- Click Chemistry and Applications
- Synthesis of heterocyclic compounds
- Synthesis and Biological Evaluation
- Organic Electronics and Photovoltaics
- Advanced NMR Techniques and Applications
- Synthesis and Properties of Aromatic Compounds
- Polyoxometalates: Synthesis and Applications
- Carbon dioxide utilization in catalysis
- Porphyrin and Phthalocyanine Chemistry
- Synthesis and Reactivity of Sulfur-Containing Compounds
Zhengzhou University
2017-2025
Southern Illinois University Carbondale
2014-2016
Activation of a catalyst [IrCl(COD)(IMes)] (IMes = 1,3-bis(2,4,6-trimethylphenyl)imidazol-2-ylidene; COD cyclooctadiene)] for signal amplification by reversible exchange (SABRE) was monitored in situ hyperpolarized proton NMR at 9.4 T. During the catalyst-activation process, moiety undergoes hydrogenation that leads to its complete removal from Ir complex. A transient hydride intermediate is observed via signatures, which could not be detected using conventional nonhyperpolarized solution...
Reusable Co-catalyzed coupling of thiols to synthesize S–N/S–S bonds in water.
The first piezochemically driven decarboxylative coupling of the C–H bond was developed. agitation BaTiO3 via ball milling converts mechanical energy into electrical potential, leading to production a benzoyl radical single-electron transfer pathway analogous photocatalytic reaction. This mechanoredox catalytic strategy synthesize C3-acylated quinoxalin-2(1H)-ones requires no solvent, short reaction time, and simple handling skills, exhibiting promising potential in large-scale chemical...
Organosulfides have great significance and value in synthetic biological chemistry. To establish a versatile green methodology for C–S bond generation, we successfully developed new aerobic cross-dehydrogenative coupling of C–H S–H to synthesize aryl sulfides water, utilizing CoPcS as the catalyst O2 oxidant. This protocol shows tolerance wide range substrates. A large variety organosulfur compounds were produced modest excellent yields.
Abstract Catalytic syntheses of organic sulfenamides and disulfides have great significance value in synthetic chemistry bioscience. To establish a versatile efficient technology for such reactions, an aerobic oxidative coupling method the formation S−N S−S bonds, using TEMPO as catalyst O 2 oxidant, has been successfully developed. Reactions showed good tolerance toward various amines thiols. Sulfenamides were produced up to 99 % yield, while formed 97 yield one‐pot syntheses. Activation...
The agitation of BaTiO3via ball milling converts mechanical energy into electrical energy, leading to the reduction molecular oxygen via a single electron transfer pathway analogous photocatalytic reaction. This mechanoredox strategy for oxidative coupling thiols could eliminate waste and develop recyclable methodology accomplish organic transformations in greener fashion, exhibiting promising potential large-scale chemical manufacturing.
We demonstrate the preparation of diacenaphthopentalene derivatives via a palladium-catalyzed dimerization 1-iodo-2-arylethynyl-acenaphthylenes. The resulting 7,14-diarylpentaleno[1,2-a:4,5a′]diacenaphthylenes, which contain four linearly fused five-membered rings, are benchtop stable and behave as hole-transporting or ambipolar semiconductors in organic field effect transistors. X-ray crystal structure shows important role naphthalene unit that enforces formal pentalene subunit at central...
The synthesis of sulfenamides <italic>via</italic> the oxidant- and metal-free electrochemical dehydrogenative coupling reaction thiols amines.
The copper complexes of PEG-grafted nitrogen ligands serve as metallomicellar nanoreactors for the aerobic tandem desilylation/Glaser coupling TMS-protected alkynes in water.
We synthesized a series of polychlorinated trityl radical substituted phenylphosphines. Through UV–vis photoluminescence (PL) spectroscopy and cyclic voltammetry, we explored the influence chemical modifications (oxidation/reduction, coordination, methylation) phosphorus center(s) on tuning optical redox properties tris(2,4,6-trichlorophenyl)methyl (TTM) framework. Those compounds hold promise for applications in coordination chemistry luminescent materials, particularly systems where both...
Utilizing direct mechanocatalytical conditions, we develop a C–H acylation of quinoline-2(1H)-one initiated by stainless-steel milling balls. A wide range functional groups are bearable, affording the desired products in excellent...
A series of PEG-functionalized nitrogen ligands were developed to conduct an aerobic oxidative cross-coupling reaction between alkyl- or aryl-hydrazines with thiols in water. This surfactant-type catalyst enables high efficiencies and selectivities, while tolerating a large variety functional groups. The mother liquor is still catalytically active after five runs.
TXPhos, a highly stable and efficient ligand designed for ppm level Pd catalyzed Suzuki–Miyaura coupling reactions under micellar conditions with TOF up to 40 000 s −1 .
An efficient and versatile Pd-catalyzed tandem C-N bond formation between aryl halides primary amines is developed. The transformation allows a one-pot synthesis of phenoxazine phenothiazine derivatives with broad range substitution patterns from readily available precursors.
An efficient and versatile Co‐catalyzed intramolecular S‐N bond formation in water to synthesize 1,2‐benzisothiazol‐3( 2H )‐one 1,2,4‐thiadiazoles derivatives good excellent yields was developed. The transformation showed great tolerance with a broad range of substituents. mother liquor able be recycled 6 times minor loss product yield.
An efficient catalytic system was developed for the acetalization and ketalization of carbonyl compounds with polyhydric alcohols under mild solvent-free conditions. In presence 0.1 mol% CoCl2 0.2 dimethylglyoxime at 70 °C 5 KPa pressure 1 h, 95.3% conversion cyclohexanone 100% selectivity corresponding cyclic ketal could be obtained, where TOF reached as high 953 h−1. It is proposed that in situ generated planartetracoordinate cobaloxime played key role cycle responsible excellent performance.
A scalable synthetic strategy to produce a large variety of unsymmetrical trisubstituted 1,3,5-triazines was developed. This protocol applied in situ formed acyl isocyanate from amide react with amidine, introducing two substituents the 1,3,5-triazinone ring low production cost and simple workup procedure. The scalability this method demonstrated by translating small-scale procedure multi-kilogram-scale synthesis. Chlorination further coupling reaction various nucleophiles could provide...
A mixed bases mediated protocol is developed to synthesize thioamides from N-aryl or N-alkylamide, aldehyde and elemental sulfur in water. This reaction requires no addition of external oxidant avoids large excess amides. Various functional groups pharmaceutically interesting heteroaromatic rings could be introduced via this efficient procedure.
Sustainable and ultrafast N -arylation of sulfoximines in water enabled by micellar catalysis.
We disclose a rapid and versatile mechanochemical method coupling gem-difluoroalkenes with thiols, yielding Z-selective monofluorovinyl sulfides. Operating solvent-free, the reaction completes within 30 s, accommodating various nucleophiles (P, N, O) overcoming F-elimination to provide α, α-difluoroalkylthioethers under base-free conditions. Mechanistic investigations indicate that base DBU abstracts proton from thiol, formation of Z-configuration being slightly more energetically favorable...
Abstract The catalytic synthesis of trans ‐hydroxystilbenes has a great significance and value in synthetic chemistry bioscience. To establish versatile efficient technology for such reactions, we successfully developed novel straightforward way the construction E ‐stilbene derivatives by rhodium‐catalyzed borylation/protonation tandem reaction using H 2 O as green hydrogen source. Various were synthesized with up to 85 % yield.