- Orthopaedic implants and arthroplasty
- Total Knee Arthroplasty Outcomes
- Orthopedic Infections and Treatments
- Balance, Gait, and Falls Prevention
- Hip disorders and treatments
- Hip and Femur Fractures
- Knee injuries and reconstruction techniques
- Lower Extremity Biomechanics and Pathologies
- Musculoskeletal pain and rehabilitation
- Dental Implant Techniques and Outcomes
- Shoulder Injury and Treatment
- Stroke Rehabilitation and Recovery
- Cerebral Palsy and Movement Disorders
- Osteoarthritis Treatment and Mechanisms
- Gait Recognition and Analysis
- Physical Activity and Health
- Non-Invasive Vital Sign Monitoring
- Musculoskeletal Disorders and Rehabilitation
- Advanced materials and composites
- Orthopedic Surgery and Rehabilitation
- Diabetic Foot Ulcer Assessment and Management
- Context-Aware Activity Recognition Systems
- Shoulder and Clavicle Injuries
- Trauma and Emergency Care Studies
- Muscle activation and electromyography studies
Luxembourg Institute of Health
2020-2025
University of California, San Francisco
2023
San Francisco General Hospital
2023
Sylvia Lawry Centre for Multiple Sclerosis Research
2019
University of Bristol
2018-2019
Atrium Medisch Centrum Parkstad
2008-2018
Zuyderland Medisch Centrum
2016-2018
Southmead Hospital
2018
Atrium Medical (Australia)
2009-2016
University of Southampton
2015
An increasing number of studies across many research fields from biomedical engineering to finance are employing measures entropy quantify the regularity, variability or randomness time series and image data. Entropy, as it relates information theory dynamical systems theory, can be estimated in ways, with newly developed methods being continuously introduced scientific literature. Despite growing interest entropic analysis, there is a shortage validated, open-source software tools that...
Wearable sensors, in particular inertial measurement units (IMUs) allow the objective, valid, discriminative and responsive assessment of physical function during functional tests such as gait, stair climbing or sit-to-stand.Applied to various body segments, precise capture time-to-task achievement, spatiotemporal gait kinematic parameters demanding specific an affected limb are most used measures.In activity monitoring (AM), accelerometry has mainly been derive energy expenditure general...
Wear particle-induced osteolysis is a major cause of aseptic loosening in THA. Increasing wear resistance polyethylene (PE) occurs by increasing the cross-link density and early reports document low rates with such implants. To confirm longer-term reductions we compared cross-linked (irradiation nitrogen, annealing) historical air) prospective, randomized clinical study involving 48 patients who underwent THAs minimum followup 7 years (mean, 8 years; range, 7-9 years). The insert material...
We have investigated the accuracy of templating digital radiographs in planning total hip replacement using two common object-based calibration methods with ball placed laterally (method 1) or medially 2) and compared them non-object-based methods. The latter comprised application a fixed magnification 121% 3) calculation based on object-film-distance 4). studied post-operative 57 patients (19 men, 38 women, mean age 73 years (53 to 89)) measured diameter prosthetic femoral head comparing it...
Knee osteoarthritis patients may become physically inactive due to pain and functional limitations. Whether physical activity exerts a protective or harmful effect depends on the frequency, intensity, time type (F.I.T.T.). The F.I.T.T. dimensions should therefore be assessed during daily life, which so far has hardly been feasible. Furthermore, within subgroups of patients, as they might experience different Therefore, this study aimed objectively describe activity, by assessing dimensions,...
Polyethylene wear-induced osteolysis is a major cause of implant loosening in total hip arthroplasty. New crosslinked polyethylenes are presumed to give lower wear rates, but no long-term clinical results available yet.We compared basic material characteristics and MTS joint simulator rates polyethylene (Duration) those conventional polyethylene. In randomized double-blind 5-year follow-up study, 133 hips (67 conventional, 66 Duration) 127 patients were followed-up for an average 5 (3-6)...
We have compared four computer-assisted methods to measure penetration of the femoral head into acetabular component in total hip replacement. These were Martell Hip Analysis suite 7.14, Rogan HyperOrtho, View Pro-X and Roman v1.70. The images used for investigation comprised 24 anteroposterior digital radiographs conventional acetate which scanned provide images. acquired from patients with an uncemented replacement a follow-up approximately eight years (mean 8.1; 6.3 9.1). Each image was...
Patients undergoing total knee replacement for end stage osteoarthritis (OA) become increasingly younger and more demanding. Consequently, outcome assessment tools need to evolve toward objective performance-based measures. We applied a novel approach ambulatory biomechanical of physical function using single inertial sensor located at the pelvis derive various motion parameters during activities daily living. investigated potential clinically feasible battery tests define relevant function....
It is important to assess physical activity objectively during daily life circumstances, understand the association between and diseases determine effectiveness of interventions. Accelerometer-based monitoring seems a promising method could potentially capture all four FITT (i.e. Frequency, Intensity, Time, Type) components considered by World Health Organization (WHO).To with an accelerometer circumstances compare self-reported levels in patients knee osteoarthritis (OA) healthy control...
OBJECTIVES To investigate the continuation rates of etonogestrel subdermal contraceptive implant among well-informed women, and reasons for early discontinuation. STUDY DESIGN Retrospective consecutive cohort design. METHODS Women who had inserted between 1 January 2006 2010 at Atrium Medical Centre, Netherlands were followed up least three years. The dates insertion removal recorded, as removal. Statistical analysis was performed using independent samples t-test Pearson alpha correlation...
Activity is increasingly being recognized as a highly relevant parameter in all areas of healthcare for diagnosis, treatment, or outcome assessment, especially orthopaedics where the movement apparatus directly affected. Therefore, aim this study was to develop, describe, and clinically validate generic activity-monitoring algorithm, satisfying combination three criteria. The algorithm must be able identify, count, time large set daily activities. It validated orthopaedic patients well...