A5070282399- Physical Activity and Health
- Obesity, Physical Activity, Diet
- Sports Performance and Training
- Balance, Gait, and Falls Prevention
- Cardiovascular and exercise physiology
- Veterinary Equine Medical Research
- Muscle activation and electromyography studies
- Diabetic Foot Ulcer Assessment and Management
- School Health and Nursing Education
- Orthopedic Surgery and Rehabilitation
- Botulinum Toxin and Related Neurological Disorders
- Health and Lifestyle Studies
- Cerebral Palsy and Movement Disorders
- Behavioral Health and Interventions
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Sports injuries and prevention
- Stroke Rehabilitation and Recovery
- Mechanics and Biomechanics Studies
- Lower Extremity Biomechanics and Pathologies
- Pain Mechanisms and Treatments
- Innovative Teaching and Learning Methods
- Musculoskeletal pain and rehabilitation
- Peripheral Artery Disease Management
- Tendon Structure and Treatment
- Body Composition Measurement Techniques
Maastricht University
2016-2025
Maastricht University Medical Centre
2012-2025
Uppsala University
2024
Uppsala University Hospital
2024
Committee on Publication Ethics
2022
University of Turku
2022
Diabetes Australia
2019-2021
Bridge University
2017
Universidad de Extremadura
2004
Universität Innsbruck
2004
There is increasing evidence that sedentary behaviour in itself a health risk, regardless of the daily amount moderate to vigorous physical activity. Therefore, should be targeted as important behaviour. It known even relatively small changes often require serious efforts from an individual and people their environment become part lifestyle. interventions promote healthy behaviours ideally simple, easy perform easily available. Since sitting likely highly habitual, confrontation with...
Satellite cells (SC) are essential for skeletal muscle growth and repair. Because sarcopenia is associated with type II fiber atrophy, we hypothesized that SC content specifically reduced in the fibers elderly. A total of eight elderly (E; 76 +/- 1 yr) young (Y; 20 healthy males were selected. Muscle biopsies collected from vastus lateralis both legs. ATPase staining a pax7-antibody used to determine type-specific (i.e., pax7-positive SC) on serial cross sections. In contrast I fibers,...
We determined muscle fiber type–specific hypertrophy and changes in satellite cell (SC) content following a 12-week resistance training program 13 healthy, elderly men (72 ± 2 years). Leg strength body composition (dual-energy X-ray absorptiometry computed tomography) were assessed, biopsy samples collected. increased 25%–30% after (p < .001). lean mass quadriceps cross-sectional area 6%–9% At baseline, mean SC smaller the Type II versus I fibers .01). Following training, from 5,438 319 to...
Background Epidemiological studies suggest that excessive sitting time is associated with increased health risk, independent of the performance exercise. We hypothesized a daily bout exercise cannot compensate negative effects inactivity during rest day on insulin sensitivity and plasma lipids. Methodology/Principal Findings Eighteen healthy subjects, age 21±2 year, BMI 22.6±2.6 kgm−2 followed randomly three physical activity regimes for four days. Participants were instructed to sit 14...
The study investigated cross-sectional associations of total amount and patterns sedentary behaviour with glucose metabolism status the metabolic syndrome.We included 2,497 participants (mean age 60.0 ± 8.1 years, 52% men) from Maastricht Study who were asked to wear an activPAL accelerometer 24 h/day for 8 consecutive days. We calculated daily time, number breaks prolonged bouts (≥30 min), average duration bouts. To determine status, underwent oral tolerance test. Associations variables...
We aimed to examine the effects of breaking sitting with standing and light-intensity walking vs an energy-matched bout structured exercise on 24 h glucose levels insulin resistance in patients type 2 diabetes. In a randomised crossover study, 19 diabetes (13 men/6 women, 63 ± 9 years old) who were not using each followed three regimens under free-living conditions, lasting 4 days: (1) Sitting: 4415 steps/day 14 sitting/day; (2) Exercise: 4823 1.1 h/day replaced by moderate-...
Although self-regulated learning (SRL) is becoming increasingly important in modern educational contexts, disagreements exist regarding its measurement. One particularly issue whether self-reports represent valid ways to measure this process. Several researchers have advocated the use of behavioral indicators SRL instead. An outstanding research debate concerns extent which it possible compare measures traditional measuring using self-report questionnaire data, and these methods provides...
Schools can help to improve children's health. The 'Healthy Primary School of the Future' (HPSF) aims sustainably integrate health and well-being into school system. This study examined effects HPSF on dietary physical activity (PA) behaviours after 1 2 years' follow-up. (n = 1676 children) has a quasi-experimental design with four intervention schools, i.e., two full (focus: nutrition PA) partial PA), control schools. Accelerometers child- parent-reported questionnaires were used at...
Abstract Background and Aims Physical inactivity, sedentary behaviour (SB), inadequate sleep are key behavioural risk factors of cardiometabolic diseases. Each is mainly considered in isolation, despite clear biological interdependencies. The aim this study was to investigate associations five-part movement compositions with adiposity biomarkers. Methods Cross-sectional data from six studies (n = 15 253 participants; five countries) the Prospective Activity, Sitting Sleep consortium were...
The kinematic patterns of head and trunk were studied in horses during induced supporting limb lameness to understand the mechanisms use compensate for evaluate different symmetry indices their significance as indicators. Using locomotion analysis system CODA-3 kinematics 11 clinically nonlame Dutch Warmblood recorded while walking (1.6 m/s) trotting (3.5 on a treadmill. A transient model, evoking pressure pain hoof sole, was used induce 3 degrees fore- hindlimb lameness. Peak vertical...
Skeletal muscle strength is often determined to evaluate the adaptive response an exercise intervention programme. Although dynamometry considered "gold standard" for assessment of in vivo, one-repetition maximum (1-RM) testing performed on training-specific equipment more commonly applied. We assessed validity specific knee extension 1-RM by comparison with a heterogeneous population (n=55). All participants tests regular leg and press machines. Additionally, isometric (at seven different...
Summary A kinematic analysis was carried out to compare treadmill and overground locomotion in horses at the trot. Stride variables limb trunk movements of 10 Dutch Warmblood were measured using CODA‐3 gait system. Overground recordings made on a rubber ground surface an asphalt track. Treadmill taken after controlled habituation programme same velocities as overground. On asphalt, shorthened stride duration decreased vertical displacement withers found compared with those ground. treadmill,...
Background: The current study investigated the moderating role of school context on effects a Dutch health promoting initiative children's and behaviors. Methods: used mixed-methods design. (n = 4) was assessed by characteristics population, teacher's health-promoting (HP) practices, implementers' perceived barriers, school's HP elements, dominating organizational issues. Outcomes included objectively BMI z-scores physical activity (PA), parent child-reported dietary intake. Analyses linear...
As accelerometers are commonly used for 24-h measurements of daily activity, methods separating waking from sleeping time necessary correct estimations total activity levels accumulated during the period. Therefore, an algorithm to determine wake and bed times in accelerometry data was developed agreement this with self-report examined. One hundred seventy-seven participants (aged 40–75 years) The Maastricht Study who completed a diary wore activPAL3™ 24 h/day, on average 6 consecutive days...
Abstract Aims/hypothesis Biomarkers of endothelial dysfunction and low-grade inflammation are important in the pathogenesis CVD can potentially be modified by physical activity sedentary behaviour. Effects on biomarkers may especially prominent type 2 diabetes. Methods In population-based Maastricht Study ( n = 2363, 51.5% male, 28.3% diabetes, 15.1% prediabetes [defined as impaired glucose tolerance fasting glucose]), we determined inflammation, combined z scores were calculated. Physical...
Abstract Aims/hypothesis The associations of sitting, standing, physical activity and sleep with cardiometabolic health glycaemic control markers are interrelated. We aimed to identify 24 h time-use compositions associated optimal metabolic determine whether these varied by diabetes status. Methods Thigh-worn activPAL data from 2388 participants aged 40–75 years (48.7% female; mean age 60.1 [SD = 8.1] years; n =684 type 2 diabetes) in Maastricht Study were examined. Compositional isometric...
To investigate the relationship between skeletal muscle fiber type-specific characteristics, circulating hormone concentrations, and mass strength in older men.Cross-sectional analyses.University research center.Forty-one community dwelling elderly men (≥ 65).Leg (1-repetition maximum, 1RM) whole-body limb were determined, type composition, cross-sectional area (CSA), myonuclear content, satellite cell (SC) content assessed biopsy samples. In addition, blood samples collected to determine...