A5051624640- Physical Activity and Health
- Cardiovascular and exercise physiology
- Cardiac Health and Mental Health
- Obesity, Physical Activity, Diet
- Cardiovascular Effects of Exercise
- Blood Pressure and Hypertension Studies
- Heart Rate Variability and Autonomic Control
- Behavioral Health and Interventions
- Stroke Rehabilitation and Recovery
- Cardiovascular Function and Risk Factors
- Health and Lifestyle Studies
- Heart Failure Treatment and Management
- Cardiovascular Health and Risk Factors
- Cardiovascular Health and Disease Prevention
- Cardiac Imaging and Diagnostics
- Nutrition and Health in Aging
- Mobile Health and mHealth Applications
- Cardiovascular Disease and Adiposity
- Diabetes Management and Research
- Long-Term Effects of COVID-19
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Acute Myocardial Infarction Research
- Dementia and Cognitive Impairment Research
- Health, Environment, Cognitive Aging
Radboud University Nijmegen
2016-2025
Radboud University Medical Center
2016-2025
Universidad de Granada
2023-2025
University Hospital and Clinics
2024-2025
University Medical Center
2016-2025
Community Care
2024-2025
European Union
2025
In-Q-Tel
2024-2025
GTx (United States)
2024
Parque Tecnológico de la Salud
2024
Physical activity and exercise training are associated with a lower risk for coronary events. However, cross-sectional studies in middle-aged older male athletes revealed increased artery calcification (CAC) atherosclerotic plaques, which were related to the amount intensity of lifelong exercise. We examined longitudinal relationship between characteristics atherosclerosis. Middle-aged men from MARC-1 (Measuring Athlete's Risk Cardiovascular Events 1) study invited follow-up MARC-2 2) study....
Abstract Background and Aims Physical inactivity, sedentary behaviour (SB), inadequate sleep are key behavioural risk factors of cardiometabolic diseases. Each is mainly considered in isolation, despite clear biological interdependencies. The aim this study was to investigate associations five-part movement compositions with adiposity biomarkers. Methods Cross-sectional data from six studies (n = 15 253 participants; five countries) the Prospective Activity, Sitting Sleep consortium were...
Blood concentrations of cardiac troponin above the 99th percentile are a key criterion for diagnosis acute myocardial injury and infarction. Troponin concentrations, even below percentile, predict adverse outcomes in patients general population. Elevated commonly observed after endurance exercise, but clinical significance this increase is unknown. We examined association between postexercise I long-distance walkers. measured 725 participants (61 [54-69] yrs) before immediately 30 to 55 km...
<h3>Importance</h3> Cardiac rehabilitation (CR) is an effective strategy to improve clinical outcomes, but it remains underused in some subgroups of patients with cardiovascular disease (CVD). <h3>Objective</h3> To investigate the implications sex, age, socioeconomic status, CVD diagnosis, cardiothoracic surgery, and comorbidity for association between CR participation all-cause mortality. <h3>Design, Setting, Participants</h3> Observational cohort study patient enrollment July 1, 2012,...
Abstract Aims/hypothesis The aim of this study was to examine the dose–response associations device-measured physical activity types and postures (sitting standing time) with cardiometabolic health. Methods We conducted an individual participant harmonised meta-analysis 12,095 adults (mean ± SD age 54.5±9.6 years; female participants 54.8%) from six cohorts thigh-worn accelerometry data Prospective Physical Activity, Sitting Sleep (ProPASS) Consortium. Associations daily walking, stair...
Individuals with coronary artery disease have poorer mental health, health-related quality of life (HR-QoL), and cognition compared (age-matched) controls. Exercise training may attenuate these effects. The aim is to systematically review meta-analyse the effects different exercise types settings on brain structure/function, cognition, HR-QoL, health (e.g. depression, anxiety), sleep in patients disease. A systematic search was conducted a network meta-analysis (i) types, high-intensity...
Moderate to vigorous physical activity (MVPA) is strongly associated with risk reductions of noncommunicable diseases and mortality. Cardiovascular health status may influence the benefits MVPA. We compare association between MVPA incident major adverse cardiovascular events (MACE) mortality healthy individuals, individuals elevated levels factors (CVRF), disease (CVD).
BackgroundSedentary behaviour (SB) is potentially an important target to improve cardiovascular health. This study 1) compared SB between disease (CVD) patients and age-matched controls, 2) identified characteristics associated with high levels, 3) determined the impact of contemporary cardiac rehabilitation (CR) on SB.MethodsFor objective 1, we recruited 131 CVD 117 controls. All participants were asked about their general medical history. was assessed by accelerometer (activPAL3 micro)....
Abstract Background A high sedentary time is associated with increased mortality risk. Previous studies indicate that replacement of light- and moderate-to-vigorous physical activity attenuates the risk for adverse outcomes improves cardiovascular factors. Patients disease are more compared to general population, while daily spent remains following contemporary cardiac rehabilitation programmes. This clinical trial investigated effectiveness a behaviour intervention as personalised secondary...
BACKGROUND: Blood pressure (BP)–lowering effects of structured exercise are well-established. Effects 24-hour movement behaviors captured in free-living settings have received less attention. This cross-sectional study investigated associations between a behavior composition comprising 6 parts (sleeping, sedentary behavior, standing, slow walking, fast and combined exercise-like activity [eg, running cycling]) systolic BP (SBP) diastolic (DBP). METHODS: Data from thigh-worn accelerometers...
Abstract Background Sedentary behavior (SB) is associated with increased risks of detrimental health outcomes. Few studies have explored correlates SB in physically active individuals. Furthermore, may depend on settings SB, such as occupation, transportation and leisure time sitting. This study aims to identify subject-, lifestyle- health-related for total different domains: transportation, time. Methods Dutch participants were recruited between June, 2015 December, 2016. Participant...
Coronavirus disease 2019 (COVID-19) lockdown restrictions may impact lifestyle and therefore also physical (in)activity patterns in patients with cardiovascular (CVD). This study aimed to evaluate the effect of on activity sedentary behaviour.A total 1565 Dutch CVD participated this prospective cohort study, which we compared behaviour before during COVID-19 period. Baseline measures were assessed 2018 data follow-up collected between 17 24 April 2020 (5 weeks after introduction...
Studies which examined the association between sedentary behavior (SB) and cognitive function have presented equivocal findings. Mentally active/inactive domains may relate differently to function. We associations SB function, specifically focusing on different domains. Participants were recruited from Nijmegen Exercise Study 2018 in Netherlands. (h/day) was measured with Sedentary Behavior Questionnaire. Cognitive assessed a validated computer self-test (COST-A), z-score calculated for...
Coronavirus disease 2019 (COVID-19) is reported to have long-term effects on cardiovascular health and physical functioning, even in the nonhospitalized population. The physiological mechanisms underlying these consequences are however less well described. We compared risk factors, arterial stiffness, functioning patients with COVID-19, at a median of 6 mo postinfection, versus age- sex-matched controls. Cardiovascular was assessed using blood pressure biomarker concentrations...
To examine the associations between muscular strength and mental health. We used baseline data of 91 cognitively healthy older adults (71.69 ± 3.91 years old, 57 % women) participating in AGUEDA randomized controlled trial. Muscular was assessed using both objective (i.e., handgrip strength, biceps curl, squats, isokinetic test) perceived International Fitness Scale) indicators. Psychological ill-being indicators: anxiety, depression, stress, loneliness; psychological well-being satisfaction...
BACKGROUND: Regular physical activity is associated with a reduced stroke risk. However, this relationship might be attenuated in the presence of hypertension and antihypertensive medication use. We examined dose-response between normotensive hypertensive individuals. METHODS: A Dutch population-based cohort including 139 930 individuals (41% men; mean age, 44±13) was performed (median follow-up, 6.75 years). Participants were stratified at baseline as (44%) or (56%) categorized into...