- Oral Health Pathology and Treatment
- Antimicrobial Peptides and Activities
- Nanoparticle-Based Drug Delivery
- Oral and Maxillofacial Pathology
- Advanced Drug Delivery Systems
- Curcumin's Biomedical Applications
- Drug Solubulity and Delivery Systems
- Facial Nerve Paralysis Treatment and Research
- RNA Interference and Gene Delivery
- Facial Trauma and Fracture Management
- Natural product bioactivities and synthesis
- Wound Healing and Treatments
- Oral microbiology and periodontitis research
- Nanoparticles: synthesis and applications
- Natural Antidiabetic Agents Studies
- 3D Printing in Biomedical Research
- Gastrointestinal disorders and treatments
- Bone Tumor Diagnosis and Treatments
- Electrospun Nanofibers in Biomedical Applications
- Diagnosis and treatment of tuberculosis
- Biochemical and Structural Characterization
- Glycosylation and Glycoproteins Research
- Analytical Methods in Pharmaceuticals
- Advanced biosensing and bioanalysis techniques
- Computational Drug Discovery Methods
National Institute of Pharmaceutical Education and Research
2021-2025
Nilai University
2024-2025
KPJ Healthcare University
2024-2025
Institute of Medical Sciences
2022-2025
BJC HealthCare
2025
Era's Lucknow Medical College and Hospital
2020-2024
Manipal Academy of Higher Education
2024
Indian Institute of Technology BHU
2022-2023
Banaras Hindu University
2022-2023
Babu Banarasi Das University
2016-2023
Background: The healing of burn wounds is a complicated physiological process that involves several stages, including haemostasis, inflammation, proliferation, and remodelling to rebuild the skin subcutaneous tissue integrity. Recent advancements in nanomaterials, especially nanofibers, have opened new way for efficient due burning or other injuries. Methods: This study aims develop characterize collagen-decorated, bilayered electrospun nanofibrous mats composed PVP PVA loaded with...
Formulation development is the most emerging and upcoming face of pharmaceutical technology in current era. It contemporarily capturing market leaps bounds with recent trends developments its innovative techniques. The day-to-day advancements research have provided an edge to this brilliant branch sector for not only uplifting pharmacy profession but also conquer diseased state nurturing health humanity. fluid-bed or air-suspension process potential tool develop newer implications...
Protein-based biomaterials, particularly amyloids, have sparked considerable scientific interest in recent years due to their exceptional mechanical strength, excellent biocompatibility and bioactivity. In this work, we synthesized a novel amyloid-based composite hydrogel consisting of bovine serum albumin (BSA) aloe vera (AV) gel utilize the medicinal properties AV circumvent its frangibility. The demonstrated an porous structure, self-fluorescence, non-toxicity, controlled rheological...
Hair follicle growth process through several well-organized stages with specific input by signaling pathways including Wnt/β-catenin and Sonic Hedgehog GSK3β in this process. As such, research focus on investigating the efficacy of molecules that are able to inhibit action inducing hair regrowth. Applying computational techniques, three compounds NMN, Resveratrol EGCG were analyzed for their inhibition. It was established has highest values molecular docking scores and, case stability...
<b>Background</b>: Oral submucous fibrosis (OSMF) is a most prevalent potentially malignant disorder associated with betel quid chewing frequently observed in the Indian population. The present study conducted much of keen interest because there new information, both press and medical literature, about benefits fresh fruits vegetables antioxidants (such as lycopene curcumin) for prevention treatment diseases. As clinicians, we often prescribe medications significant adverse effects,...
Diabetes is a major health challenge, and it linked to number of serious issues, including cardiovascular disease (heart attack stroke), diabetic nephropathy (kidney damage or failure), birth defects. The detection glucose has direct significant clinical importance in the management diabetes. Herein, we demonstrate application in-situ synthesized Ti2C-TiO2 MXene nanocomposite for high throughput non-enzymatic electrochemical sensing glucose. was by controlled oxidation Ti2C-MXene nanosheets...
Cytotoxicity, a major obstacle in therapeutic application of antimicrobial peptides, is controlled by leucine-zipper-like sequences melittin and other naturally occurring peptides. Magainin 2 shows significantly lower cytotoxicity than many peptides lacks this structural element. To investigate the consequences introducing leucine zipper sequence magainin 2, novel analogue (Mag-mut) was designed rearranging only positions its hydrophobic amino acids to include Both Mag-mut showed appreciable...
The bee venom antimicrobial peptide, melittin, besides showing versatile activity against microorganisms also neutralizes lipopolysaccharide (LPS)-induced proinflammatory responses in macrophage cells. However, how the amino acid sequence of melittin contributes its anti-inflammatory properties is mostly unknown. To determine importance leucine zipper neutralization LPS-induced inflammatory macrophages and interaction with LPS, three analogues their interactions LPS were studied detail. Two...
The goals of treating ulcerative colitis (UC) have shifted from clinical remission to mucosal healing. Non-invasive biomarkers are required assess healing as endoscopic assessment is inconvenient for patients. Enhanced expression trefoil factor 3 (TFF3, a mucin-associated peptide) observed after injury the gastrointestinal tract. present study was designed evaluate TFF3 biomarker in patients with UC.This cross-sectional included consecutive UC (18-65 years old, disease duration >3 months,...
Chronic periodontitis has an interplay between different species of bacteria found in dental biofilms act a crucial role pathogenesis and disease progression. The existing antibacterial therapy is inadequate, associated with many side effects as well evolving multidrug resistance. Hence, novel drugs development minimum or no toxicity immediate priority.Antibacterial efficacy ethanolic extract Matricaria aurea was tested against clinical isolates, ie. Treponema denticol, Tannerella forsythia,...