A5052993106- Cardiovascular Disease and Adiposity
- Neutrino Physics Research
- Astrophysics and Cosmic Phenomena
- Cardiac Valve Diseases and Treatments
- Atrial Fibrillation Management and Outcomes
- Cardiovascular Function and Risk Factors
- Cardiac Arrhythmias and Treatments
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Dark Matter and Cosmic Phenomena
- Heart Failure Treatment and Management
- Cardiovascular Effects of Exercise
- Cardiomyopathy and Myosin Studies
- Cardiac Imaging and Diagnostics
- Particle physics theoretical and experimental studies
- COVID-19 Clinical Research Studies
- Venous Thromboembolism Diagnosis and Management
- Adipokines, Inflammation, and Metabolic Diseases
- Atherosclerosis and Cardiovascular Diseases
- Adipose Tissue and Metabolism
- Cardiac Ischemia and Reperfusion
- Infective Endocarditis Diagnosis and Management
- Receptor Mechanisms and Signaling
- Gamma-ray bursts and supernovae
- Long-Term Effects of COVID-19
- Antiplatelet Therapy and Cardiovascular Diseases
Istituto Nazionale di Fisica Nucleare, Sezione di Genova
2023-2025
University of Salerno
2015-2025
University of Genoa
2023-2025
University College London
2012-2025
University of Naples Federico II
2014-2024
Federico II University Hospital
2012-2024
Czech Technical University in Prague
2024
Comenius University Bratislava
2024
Columbia University
2019-2023
Casa di Cura San Michele
2016-2021
It has been reported that epicardial adipose tissue (EAT) may affect myocardial autonomic function.The aim of this study was to explore the relationship between EAT and cardiac sympathetic nerve activity in patients with heart failure.In 110 systolic failure, we evaluated correlation echocardiographic thickness adrenergic assessed by (123)I-metaiodobenzylguanidine ((123)I-MIBG). The predictive value on denervation ((123)I-MIBG early late heart:mediastinum ratio single-photon emission...
Abstract In Europe, multiple waves of infections with SARS-CoV-2 (COVID-19) have been observed. Here, we investigated whether common patterns cytokines could be detected in individuals mild and severe forms COVID-19 two pandemic waves, machine learning approach useful to identify the best predictors. An increasing trend was observed patients or severe/critical symptoms COVID-19, compared healthy volunteers. Linear Discriminant Analysis (LDA) clearly recognized three groups based on cytokine...
Background— Impaired angiogenesis in the post-myocardial infarction heart contributes to progression failure. The inhibition of vascular endothelial growth factor (VEGF) signaling has been shown be crucial for transition from compensatory hypertrophy cardiac Importantly, β-adrenergic receptor blocker therapy also improve myocardial perfusion by enhancing neoangiogenesis failing heart. Methods and Results— Eight weeks surgically induced infarction, failure rats were randomized receive...
Sympathetic nervous system hyperactivity is associated with poor prognosis in patients heart failure (HF), yet routine assessment of sympathetic activation not recommended for clinical practice. Myocardial G protein-coupled receptor kinase-2 (GRK2) upregulated HF patients, causing dysfunctional β-adrenergic signaling. Importantly, myocardial GRK2 levels correlate found peripheral lymphocytes patients.The independent prognostic value blood measurements has never been investigated; thus, the...
Background and aims: Post-operative atrial fibrillation (POAF), defined as new-onset AF in the immediate period after surgery, is associated with poor adverse cardiovascular events a higher risk of permanent AF. Mechanisms leading to POAF are not completely understood epicardial adipose tissue (EAT) inflammation could be potent trigger. Here, we aim at exploring link between EAT-secreted interleukin (IL)-1β, remodeling, population coronary artery disease (CAD) patients. Methods: We collected...
Amyloid deposition within stenotic aortic valves (AVs) also appears frequent in the absence of cardiac amyloidosis, but its clinical and pathophysiological relevance has not been investigated. We will elucidate rate isolated AV amyloid potential significance stenosis (AS). In 130 patients without systemic and/or we collected explanted AVs during surgery: 57 with calcific AS 73 insufficiency (41 sclerosis 32 without, who were used as controls). was found 21 (37%), 4 sclerotic (10%), none...
Left ventricular (LV) diastolic dysfunction is linked to myocardial collagen content in many cardiac diseases. There are no data regarding such relationship patients with end-stage renal disease (ESRD) undergoing haemodialysis.Twenty-five ESRD haemodialysis were studied by echocardiography. LV function was investigated Doppler echocardiography, analysing filling velocities at rest and during loading manoeuvres, which represent an estimate of pressure. According the pattern, pressure a given...