A5039947836- Glioma Diagnosis and Treatment
- Plant-based Medicinal Research
- Saffron Plant Research Studies
- Medical Imaging Techniques and Applications
- Meningioma and schwannoma management
- Brain Metastases and Treatment
- Radiomics and Machine Learning in Medical Imaging
Martinsburg VA Medical Center
2022
West Virginia University
2022
Currently, contrast-enhancing margins on T1WI are used to guide treatment of gliomas, yet tumor invasion beyond the region is a known confounding factor. Therefore, this study postmortem tissue samples aligned with clinically acquired MRIs quantify relationship between intensity values and cellularity as well develop radio-pathomic model predict using MR imaging data.This single-institution 93 collected at examination from 44 patients brain cancer. Tissue were processed, stained H&E,...
Glioblastoma multiforme tumors typically exhibit regions of hypoxia. Hypoxic within the tumor make cells less sensitive to radiosurgery and radiation therapy. Trans sodium crocetinate (TSC) has been shown be a radiosensitizer. The goal this research was elucidate underlying mechanism TSC's radiosensitizing effect.A rat C6 glioma model used. were stereotactically injected into brain create tumor. Two weeks later, MR imaging used confirm presence glioma. Following demonstration on tumor,...
Limited retrospective data exist on malignant pineal parenchymal tumors (PPTs) in adults, and there are no large previous studies that review clinical outcomes across the 3 treatment arms of surgery, radiotherapy, chemotherapy. As a result, optimal disease management has yet to be defined.To evaluate trends perform survival analysis adult PPT.The National Cancer Database was queried for histologically confirmed PPT diagnosed from 2007 2016. Univariate multivariate Cox regressions were used...