A5101744614- Lipid Membrane Structure and Behavior
- Force Microscopy Techniques and Applications
- Semiconductor materials and devices
- RNA Interference and Gene Delivery
- Advanced biosensing and bioanalysis techniques
- Molecular Junctions and Nanostructures
- Nanoplatforms for cancer theranostics
- Advanced Memory and Neural Computing
- Ferroelectric and Negative Capacitance Devices
- Copper Interconnects and Reliability
- Silicon and Solar Cell Technologies
- Thin-Film Transistor Technologies
- Parallel Computing and Optimization Techniques
- Advancements in Semiconductor Devices and Circuit Design
- Advanced Data Storage Technologies
- Polymer Surface Interaction Studies
- Education and Learning Interventions
- Plasma Diagnostics and Applications
- Electrochemical sensors and biosensors
- Gold and Silver Nanoparticles Synthesis and Applications
- Technology and Data Analysis
- Mechanical and Optical Resonators
- Distributed and Parallel Computing Systems
- Cancer, Hypoxia, and Metabolism
- Electrochemical Analysis and Applications
Seoul National University
2007-2025
Korea Electronics Technology Institute
2024
Seoul National University of Science and Technology
2013-2024
Yonsei University
2015-2024
SK Group (South Korea)
2012-2022
Korea University of Science and Technology
2022
Seoul Institute
2020
Government of the Republic of Korea
2020
Defense Acquisition Program Administration
2018
Sungkyunkwan University
2011-2016
Resistive-switching and current conduction mechanisms have been studied in TiN/Ti/TiOx/HfOx/TiN resistive-switching random access memories (RRAMs). From I-V characteristics temperature measurement, thermionic emission is found to be the most appropriate mechanism representing dominant all bias regions resistance states. Low-frequency noise power spectrum measured analyze accurately mechanism, which corroborates thermionic-emission. Also, using migration of oxygen ions depending on polarity...
Spin-transfer torque magnetic RAM (STT-MRAM) is one of the most promising nonvolatile memories with guaranteed high-speed read and write operations. Along performance improvements in tunnel magnetoresistance (TMR) junction's (MTJ) required switching current, there have also been reports on high-capacity (up to tens Mb) STT-MRAM [1-4]. In [2] a perpendicular-TMR (pMTJ) device used reduce current sense amplifier proposed. [3] 54nm 2T-1MTJ 14F <sup xmlns:mml="http://www.w3.org/1998/Math/MathML"...
In obesity, the interactions between proinflammatory macrophages and adipocytes in white adipose tissues are known to play a crucial role disease progression by providing inflammatory microenvironments. Here, we report that functional nanoparticle-mediated modulation of crosstalk can remodel adipocyte immune As nanomodulator, designed antivascular cell adhesion molecule (VCAM)-1 antibody-conjugated amlexanox-loaded polydopamine nanoparticles (VAPN). Amlexanox was used as model drug increase...
Herein, a tolerogenic nanovaccine is developed and tested on an animal model of multiple sclerosis. The constructed to deliver the self-antigen, myelin oligodendrocyte glycoprotein (MOG) peptide, dexamethasone abatacept-modified polydopamine core nanoparticle (AbaLDPN-MOG). AbaLDPN-MOG can target dendritic cells undergo endocytosis followed by trafficking lysosomes. blocks interaction between CD80/CD86 CD28 in antigen-presenting T cells, leading decreased interferon gamma secretion....
Silica surfaces modified with nitrilotriacetic acid (NTA)-polyethylene glycol (PEG) derivatives were used to immobilize hexahistidine-tagged green fluorescent protein (His6-GFP), biotin/streptavidin-AlexaFluor555 (His6-biotin/SA-AF), and gramicidin A-containing vesicles (His6-gA). Three types of surface-reactive PEG derivatives−NTA-PEG3400-Si(OMe)3, NTA-PEG3400-vinylsulfone, mPEG5000-Si(OMe)3 (control)−were grafted onto silica tested for their ability capture His6-tag species via...
Random telegraph noise (RTN) has been studied in amorphous TiOx (α-TiOx) resistance switching random access memories (RRAMs). The RTN having two discrete current levels was observed only the high-resistance state of RRAMs. By investigating bias dependence capture and emission time constants, we extracted vertical location a trap responsible for RRAM devices. causing found around 5.7 nm below Ti (top electrode). energy less by 0.18 eV than conduction band edge TiOx.
We present the regenerative label-free fiber optical biosensor that exploits surface plasmon resonance for quantitative detection of fibrinogen (Fbg) extracted from human blood plasma.The sensor head was made up a multimode with its polymer cladding replaced by metal composite nanometer thickness silver, aluminum, and nickel. The Ni layer coated allowed direct immobilization histidine-tagged peptide (HP) on without an additional cross-linker in between. On HP layer, immunoglobulin G then...
In this study, we sought to design a bionanomaterial that could exert anticancer effects against primary tumors and protect rechallenged via photodynamic immunotherapy. As biomaterial, used an amphiphilic phenylalanine derivative of poly-gamma glutamic acid, which forms nanoparticles by self-assembly. For effects, co-entrapped hydrophobic chlorin e6 monophosphoryl lipid A in the core plain (AN), generate M/C/AN. comparison, AN e6-loaded (C/AN). vitro studies showed B16F10 cancer cells...
This study proves the applicability of wafer to hybrid bonding commercialized DRAM products for first time. A metal interconnection process Cu pad was carried out on already fabricated and another bare Si wafer. Two wafers were stacked with process. Afterwards, TSV last BEOL Metallization out. After applying optimized conditions CMP flatness, dishing control, voids free confirmed. The stable connectivity could be confirmed through daisy chain pattern 100% pass rate. Finally same yields...
Abstract Here, a tannic acid‐based nanomaterial is developed for treating rheumatoid arthritis by inducing antigen‐specific immune tolerance. The tolerogenic nanovaccine designed targeted delivery of dexamethasone and citrullinated peptide in lipid‐coated nanoparticle consisting acid as core (CitDTN). surface CitDTN modified with abatacept to yield AbaCitDTN. Abatacept modification enables the target dendritic cells interacting co‐stimulatory molecules, CD80 CD86. This increases lymph node...
Abstract Current treatments for autoimmune diseases often involve broad‐acting immunosuppressants, which carry risks such as infections and malignancies. This study investigates whether exosomes derived from anti‐inflammatory macrophages (AE) decorated with myelin oligodendrocyte glycoprotein (MOG) peptide (AE/M) can induce immune tolerance in diseases. Experimental encephalomyelitis (EAE), a mouse model multiple sclerosis, serves the disease model. Exosomes myoblasts or fibroblasts are also...
Inspired by the survival strategies of pyomelanin-producing microbes, we synthesize pyomelanin nanoparticles (PMNPs) from homogentisic acid- γ-lactone via auto-oxidation and investigate their biomedical potential. PMNPs possess distinct physicochemical properties, including reactive oxygen species scavenging microenvironment-responsive self-disassembly. Under intestinal conditions, self-disassemble penetrate nanoscale pores mucin layer. In an inflammatory bowel disease model, orally...
Abstract Colorectal cancer is characterized by high rates of recurrence and metastasis, making it particularly challenging to manage due multidrug resistance after treatment and/or the difficulty detecting metastatic lesions. Photothermal therapy (PTT) has emerged as a promising strategy overcome drug resistance, with ongoing studies investigating its potential induce abscopal effect—an immune-mediated response targeting cancer. However, current research indicates that PTT alone insufficient...