A5055032191- Pharmaceutical Practices and Patient Outcomes
- Pharmaceutical studies and practices
- Monetary Policy and Economic Impact
- Health Systems, Economic Evaluations, Quality of Life
- Pharmaceutical Economics and Policy
- Pharmacovigilance and Adverse Drug Reactions
- Global Financial Crisis and Policies
- Fiscal Policies and Political Economy
- Antibiotic Use and Resistance
- Schizophrenia research and treatment
- Medication Adherence and Compliance
- Treatment of Major Depression
- Fiscal Policy and Economic Growth
- Pharmacological Effects and Toxicity Studies
- Patient Satisfaction in Healthcare
- Pharmaceutical industry and healthcare
- Drug-Induced Adverse Reactions
- Suicide and Self-Harm Studies
- Market Dynamics and Volatility
- Diabetes Treatment and Management
- Mental Health Treatment and Access
- Economic Policies and Impacts
- Opioid Use Disorder Treatment
- Asthma and respiratory diseases
- Child and Adolescent Health
Karolinska Institutet
2012-2023
Karolinska University Hospital
2013-2023
University of Copenhagen
2011-2021
Copenhagen Business School
2019
Stockholm University College of Music Education
2017
Uppsala University
1991-2006
Medical Products Agency
1998-2003
Stockholm County Council
2003
Centre for Palaeogenetics
2003
Integrated Cardio Metabolic Centre
1997-2001
To describe the content and potentials of new Swedish national register on prescribed dispensed medicines.The Prescribed Drug Register contains information about age, sex unique identifier patient as well prescriber's profession practice. Information regarding drug utilization expenditures for drugs in entire population was extracted from first six months July-December 2005 compared with total sales country including OTC hospital use.The quantity sold Sweden 2666 million DDDs, corresponding...
Exposure to Benzodiazepines (BZD) during foetal life has been suggested contribute neonatal morbidity and some congenital malformations, for example, orofacial clefts. Here we aimed study the outcome malformations in neonates whose mothers reported use of BZD and/or hypnotic benzodiazepine receptor agonists (HBRA) pregnancy.In Swedish Medical Birth Register identified 1979 infants (n = 1944) HBRA early pregnancy. An additional 401 were studied, born 390 who prescribed such drugs late...
Abstract: The aim was to present and evaluate the impact of a comprehensive strategy over 10 years select, communicate achieve adherence essential drug recommendations (EDR) in ambulatory care metropolitan healthcare region. EDRs were issued launched as ‘Wise List’ by regional Drug Therapeutics Committee Stockholm. This study presents concept by: (i) documenting process for selecting, communicating monitoring List’; (ii) analysing variation number substances recommended between 2000 2010;...
To examine the risk of neurological and autoimmune disorders special interest in people vaccinated against pandemic influenza A (H1N1) with Pandemrix (GlaxoSmithKline, Middlesex, UK) compared unvaccinated over 8-10 months.Retrospective cohort study linking individualised data on vaccinations to an inpatient specialist database healthcare utilisation Stockholm county for follow-up during after period.Stockholm county, Sweden. Population All registered 1 October 2009 who had lived this region...
<b>Objective</b> To assess the risk of attempted suicide before, during, and after treatment with isotretinoin for severe acne. <b>Design</b> Retrospective cohort study linking a named patient register users (1980-9) to hospital discharge cause death registers (1980-2001). <b>Setting</b> Sweden, 1980-2001. <b>Population</b> 5756 patients aged 15 49 years prescribed acne observed 17 197 person 2905 87 120 treatment. <b>Main outcome measures</b> Standardised incidence ratio (observed number...
Ascertain the extent of differences between men and women in dispensed drugs since there is a lack comprehensive overviews on sex use prescription drugs.
Summary: Purpose: Because frequent seizures constitute a major risk factor for sudden unexpected death in epilepsy (SUDEP), the treatment with antiepileptic drugs (AEDs) may play role occurrence of SUDEP. We used data from routine therapeutic drug monitoring (TDM) to study association between various aspects AED and Methods: A nested case–control was based on cohort consisting 6,880 patients registered Stockholm County In Ward Care Register diagnosis epilepsy. Fifty‐seven SUDEP cases, 171...
<h3>Abstract</h3> <b>Objective</b>: To analyse the outcome of depression in Swedish population as reflected by detection antidepressants a national forensic toxicological screening programme unnatural deaths. <b>Design</b>:Antidepressants detected National Laboratory Forensic Chemistry were related to data on use expressed person years exposure. <b>Subjects</b>: All 7000 cases death with results from 1990-1; this included 3400 (85%) 4000 suicide Sweden. <b>Main measures</b>:Number findings...
Adverse drug reactions (ADRs) to phenformin and metformin reported the Swedish Drug Reaction Committee during 1965--77 were analysed in relation sales prescription data. The biguanides accounted for 0.6% of all adverse but 6% fatal cases (all phenformin). Sixty-four ADRs eight classified as causal "probable" or "not excluded." Fifty-one these (71%) lactic acidosis, one being phenformin. After 1973 was prescribed less Sweden became predominant. A nationwide survey 1975--6 disclosed no...
The increased access to medicinal products in Africa is not well-matched with the pharmacovigilance capacity monitor drug safety. objective of this study was assess functionality and identify strengths limitations national systems Ethiopia, Kenya, Rwanda, Tanzania, compare these systems. Legal statutory documents governing each participating country were examined by assessors prior on-site review. staff unit National Medicines Regulatory Authorities (NMRAs) interviewed using East African...
Antidepressants detected by the National Department of Forensic Chemistry in 5281 suicides Sweden during period 1992‐1994 were related to data on usage expressed person‐years exposure. 874 subjects (16.5%). In relation their use, fluvoxamine, citalopram, moclobemide, mianserin and trimipramine found more often than reference drug, amitriptyline (i.e. over‐risks). Toxic concentrations antidepressants 232 (4.4%). Most people committing suicide not taking immediately before death, even though...
Abstract The use of antidepressants has been low in Jämtland County for many years, while the suicide rate among highest Sweden. A continuous outpatient prescription recording system operation since 1970. Through this we traced pattern 80 individuals who committed from 1970 to 1984. Suicide patients obtained 1.5 times more drugs than matched controls, mainly psychotropics and vitamins. During 3 months prior suicide, half had received medical attention 73% women 40% men drugs, one‐third...
Abstract In order to explore a priori hypotheses about drug‐induced Stevens‐Johnson Syndrome (SJS), case‐ontrol study was initiated using data from COMPASS R , computerized base consisting of Medicaid claims data. The records 3.8 million patients in five U.S. states were searched identify with an inpatient diagnosis ICD‐9‐M code 695.1 (erythema multiforme‐EM). Out the total 367 cases that identified, primary medical for 249 sought and 128 (51.4 per cent) these obtained. remainder could not...