A5025091575- SARS-CoV-2 and COVID-19 Research
- SARS-CoV-2 detection and testing
- Periodontal Regeneration and Treatments
- Gut microbiota and health
- Biosensors and Analytical Detection
- Bone Tissue Engineering Materials
- Clostridium difficile and Clostridium perfringens research
- Gastroesophageal reflux and treatments
- Clinical Nutrition and Gastroenterology
- Medical and Biological Ozone Research
- High Altitude and Hypoxia
- Helicobacter pylori-related gastroenterology studies
- COVID-19 Clinical Research Studies
- Facial Trauma and Fracture Management
- Dental Implant Techniques and Outcomes
- Spaceflight effects on biology
- Liver Disease Diagnosis and Treatment
- Mesenchymal stem cell research
- Bone health and treatments
- Connective tissue disorders research
- Drug Transport and Resistance Mechanisms
- Tissue Engineering and Regenerative Medicine
- Neonatal Health and Biochemistry
- Viral gastroenteritis research and epidemiology
Federal Medical-Biological Agency
2022-2024
Ministry of Health of the Russian Federation
2020
P.A. Hertzen Moscow Oncology Research Institute
2019
Introduction The new coronavirus disease, COVID-19, poses complex challenges exacerbated by several factors, with respiratory tissue lesions being notably significant among them. Consequently, there is a pressing need to identify informative biological markers that can indicate the severity of disease. Several studies have highlighted involvement proteins such as APOA1, XPNPEP2, ORP150, CUBN, HCII, and CREB3L3 in these lesions. However, lack information regarding antibodies human body, which...
Human platelet lysate (HPL) is a promising alternative to fetal calf serum (FCS) for the expansion of adipose tissue mesenchymal stromal cells (AT-MSCs) translational medicine applications. However, some biological effects HPL are still be elucidated. We aimed compare complex characteristics, such as cell morphology, proliferative activity, differentiation potential, and especially monolayer recovery, DNA integrity, gene expression pattern, between AT-MSCs cultured with or FCS. Primary...
Background: The pandemic of the new coronavirus infection, COVID-19, is currently ongoing in world. Over years, pathogen, SARS-CoV-2, has undergone a series mutational genome changes, which led to spread various genetic variants virus. Meanwhile, methods used diagnose establish disease stage and assess immunity, are nonspecific SARS-CoV-2 time-consumable. Thus, development for diagnosing as well their implementation practice, an important direction. In particular, application systems based...
Background: Secondary immunodeficiency in recipients after allogeneic hematopoietic stem cell transplantation (allo-HSCT) the pediatric practice is often accompanied by bacterial and viral infections of gastrointestinal tract (GIT), resistant to conventional therapy. Fecal microbiota (FMT) promotes intestinal recolonization eradication symptoms. Clinical case description: A 2.5-year-old patient underwent allo-HSCT from a haploidentical related donor (father) as part treatment acute myeloid...
In ENT clinical practice, there are cases of a disease similar to those ones chronic adenotonsillitis, but insensitive the designated conservative therapy. This was first described in 1987 and is called PFAPA syndrome. Its symptoms periodicity its regression when corticosteroids prescribed were established. Adenotomy/adenotonsillectomy can eliminate or significantly reduce frequency relapses. The histological features structure palatine pharyngeal tonsils, as well characteristics...
Introduction . The increasing duration of spaceflights and the associated prolonged exposure space crewmembers to unfavorable microgravity conditions necessitate development improved approaches diagnosing health status directly during flight. This study is aimed at searching selecting promising biological markers suitable for studying spaceflights. Objective To review current abovementioned problem identify biochemical molecular most biomedical research in spaceflight conditions. Methods A...
Background: The immune response to SARS-CoV-2 includes the production of specific immunoglobulins protein antigens SARS-CoV-2. Depending on type and level immunoglobulins, it is possible assess stage disease evaluate effectiveness vaccination. main approach determination in human biological fluids enzyme-linked sorbent immunoassay. Its data, particular, are used issue an electronic COVID-19 certificate with a QR code. However, qualitative quantitative composition for code not officially...
Fecal microbiota transplantation (FMT) is prescribed to treat various gastrointestinal pathologies. One of the most important and significant stages FMT selection donor. In recent years, special attention has been paid checking biomaterial for genes marking resistance groups antibiotics. This study aimed analyze occurrence mef ermB drug genetic markers in population age groups, including breastfed infants, determine microbiological composition flora distal part intestine potentially healthy...