A5090060645- Bone Tissue Engineering Materials
- 3D Printing in Biomedical Research
- Dental Implant Techniques and Outcomes
- Orthopaedic implants and arthroplasty
- Additive Manufacturing and 3D Printing Technologies
- Facial Trauma and Fracture Management
- Calcium Carbonate Crystallization and Inhibition
- Endodontics and Root Canal Treatments
- biodegradable polymer synthesis and properties
- Periodontal Regeneration and Treatments
- Magnesium Oxide Properties and Applications
- Dental materials and restorations
- Mesenchymal stem cell research
- Cancer Cells and Metastasis
- X-ray Diffraction in Crystallography
- Layered Double Hydroxides Synthesis and Applications
- Crystallization and Solubility Studies
- Ferrocene Chemistry and Applications
- Advanced Topics in Algebra
- Marine Biology and Environmental Chemistry
- Metal complexes synthesis and properties
- Bone health and treatments
- Cancer, Stress, Anesthesia, and Immune Response
- Planetary Science and Exploration
- Spaceflight effects on biology
Ministry of Health of the Russian Federation
2016-2025
P.A. Hertzen Moscow Oncology Research Institute
2015-2025
Medical Radiological Research Center
2016-2021
Tver State Technical University
2020
Baikov Institute of Metallurgy and Materials Science
2017
Pirogov Russian National Research Medical University
2017
Theratechnologies (Canada)
2008
Federal Medical-Biological Agency
2008
Bioprinting can be defined as additive biofabrication of three-dimensional (3D) tissues and organ constructs using tissue spheroids, capable self-assembly, building blocks. The thyroid gland, a relatively simple endocrine organ, is suitable for testing the proposed bioprinting technology. Here we report functional vascularized mouse gland construct from embryonic spheroids proof concept. Based on self-assembly principle, generated starting (TS) allantoic (AS) source thyrocytes endothelial...
Abstract The toxicity of ferrocenylethyl benzotriazole ( 1 ) and other ferrocene compounds including ferrocenylmethyl benzimidazoles 4,5,6,11 ), ferricenium salts 3,9,10 adenine 7 was studied. All complexes under investigation showed low or medium toxicities. On the basis an earlier model chemical carcinogenesis, antitumor activity ferrocenylalkyl azoles 1, 8 9, 10 studied in vivo so‐called sub‐capsular test on human tumors. This effectiveness compared with that cisplatin. A series were...
Mesoporous hydroxyapatite (HA) and iron(III)-doped HA (Fe-HA) are attractive materials for biomedical, catalytic, environmental applications. In the present study, nanopowders of Fe-HA with a specific surface area up to 194.5 m2/g were synthesized by simple precipitation route using iron oxalate as source Fe3+ cations. The influence amount on phase composition, powders morphology, Brunauer–Emmett–Teller (BET) (S), pore size distribution investigated, well electron paramagnetic resonance...
Octacalcium phosphate (OCP), a new-generation bone substitute material, is considered precursor of the biological apatite. The two-layered structure OCP contains apatitic and hydrated layers intensively involved in ion-exchange surface reactions, which results hydrolysis to hydroxyapatite adsorption ions or molecular groups presented environment. During various vitro procedures, such as biomaterial solubility, additive release studies, functionalization technique, several model solutions are...
Sr2+-substituted β-tricalcium phosphate (β-TCP) powders were synthesized using the mechano-chemical activation method with subsequent pressing and sintering to obtain ceramics. The concentration of Sr2+ in samples was 0 (non-substituted TCP, as a reference), 3.33 (0.1SrTCP), 16.67 (0.5SrTCP) mol.% expected Ca3(PO4)2, Ca2.9Sr0.1(PO4)2, Ca2.5Sr0.5(PO4)2 formulas, respectively. chemical compositions confirmed by energy-dispersive X-ray spectrometry (EDX) inductively coupled plasma optical...
We consider a superalgebra with superinvolution or graded involution $\#$ over field $F$ of characteristic zero and assume that it is $PI$-algebra. In this paper, we present the proof version celebrated hook theorem \cite{SAR} for case multilinear $\#$-superidentities. This provides important combinatorial characteristics identities in language symmetric group representations. Furthermore, an analogue Amitsur $\#$-superalgebras, which are polynomial interpretations mentioned characteristics,...
The development of specific MRI criteria to monitor the implantation process may provide valuable information individual tissue response. Using and histological methods, biointegration carbon-carbon (C-C) composites into subcutaneous tissues BDF1 mice their biocompatibility were investigated. study focused on autopsy specimens containing C-C composite implants, both uncoated coated with synthetic hydroxyapatite (Ca-P) via electrodeposition or detonation techniques, assessed at 6 12 weeks...
Nanocrystalline 3 mol% yttria-tetragonal zirconia polycrystal (3Y-TZP) ceramic powder containing 5 wt.% Al2O3 with 64 m2/g specific area was synthesized through precipitation method. Different amounts of Co (0–3 mol%) were introduced into powders, and materials obtained by heat treatment in the air for 2 h at 1350–1550 °C. The influence addition on sintering temperature, phase composition, microstructure, mechanical biomedical properties composite materials, resolution digital light...
Powders based on β-tricalcium phosphate (β-TCP) containing sulphate groups at up to 12.0 mol.% were synthesised by chemical precipitation from aqueous solutions. The obtained materials characterised X-ray phase analysis, Fourier transform infrared spectroscopy, measurement of specific surface area, scanning electron microscopy, energy dispersive synchronous thermal mass spectra investigations and biological assays. It was established that during the synthesis, lose in course heat treatment...
The development of magnesium calcium phosphate bone cements (MCPCs) has garnered substantial attention. MCPCs are bioactive and biodegradable have appropriate mechanical antimicrobial properties for use in reconstructive surgery. In this study, the cement powders based on a (Ca + Mg)/P = 2 system doped with Zn2+ at 0.5 1.0 wt.% were obtained investigated. After mixing liquid, structural phase composition, morphology, chemical structure, setting time, compressive strength, degradation...
Despite a long period of application metal implants, carbon-carbon medical composites are also widely used for bone defect prosthesis in surgery, dentistry, and oncology. Such implants might demonstrate excellent mechanical properties, but their biocompatibility integration efficiency into the host should be improved. As method enhancing, electrophoretic deposition fine-dispersed hydroxyapatite (HAp) on porous carbon substrates recommended. With electron microscopy, energy dispersion X-ray...
Bones are the fourth most frequent site of metastasis from malignant tumors, including breast cancer, prostate melanoma, etc. The bioavailability bone tissue for chemotherapy drugs is extremely low. This requires a search new approaches targeted drug delivery to tumor growth zone after surgery treatment. aim this work was develop method octacalcium phosphate (OCP) graft functionalization with cytostatic cisplatin provide local release its therapeutic concentrations into defect. OCP porous...
Human platelet lysate (HPL) is a promising alternative to fetal calf serum (FCS) for the expansion of adipose tissue mesenchymal stromal cells (AT-MSCs) translational medicine applications. However, some biological effects HPL are still be elucidated. We aimed compare complex characteristics, such as cell morphology, proliferative activity, differentiation potential, and especially monolayer recovery, DNA integrity, gene expression pattern, between AT-MSCs cultured with or FCS. Primary...
The development of magnesium calcium phosphate bone cements (MCPCs) have garnered big attention. MCPCs are bioactive and biodegradable appropriate mechanical antimicrobial properties for use in reconstructive surgery. In this study, the cement powders based on a (Ca + Mg)/P = 2 system doped with Zn2+ at 0.5 1.0 wt.% were obtained investigated. After mixing liquid, structural phase composition, morphology, chemical structure, setting time, compressive strength, degradation behavior,...