A5017654767- Viral gastroenteritis research and epidemiology
- Animal Virus Infections Studies
- Viral Infections and Immunology Research
- Hepatitis Viruses Studies and Epidemiology
- Virus-based gene therapy research
- Veterinary medicine and infectious diseases
- Fecal contamination and water quality
- Respiratory viral infections research
- Infection Control and Ventilation
- Listeria monocytogenes in Food Safety
- Liver Disease and Transplantation
- Mycobacterium research and diagnosis
- Streptococcal Infections and Treatments
- Child Nutrition and Water Access
- Clostridium difficile and Clostridium perfringens research
- Neonatal and Maternal Infections
- Probiotics and Fermented Foods
- Gut microbiota and health
- SARS-CoV-2 and COVID-19 Research
- SARS-CoV-2 detection and testing
- Salmonella and Campylobacter epidemiology
- Bacteriophages and microbial interactions
- Infective Endocarditis Diagnosis and Management
- Plant Virus Research Studies
- Food Safety and Hygiene
Agriculture and Agri-Food Canada
2014-2024
Université de Montréal
2001-2024
Saint-Hyacinthe Research and Development Centre
2011-2022
Natural Sciences and Engineering Research Council
2016
Health Canada
2009
Canadian Food Inspection Agency
2004
Concordia University
1988
This study evaluated the presence of pathogenic human and zoonotic viruses on irrigated, field-grown strawberries. Norovirus genogroup I, rotavirus, swine hepatitis E virus 3 were detected strawberries, irrigation water is suspected as contamination origin.
Chronic hepatitis E virus (HEV) infection has been described in immunosuppressed adult patients. A study was undertaken to establish the presence of HEV children after orthotopic liver transplantation (OLT).Children undergoing between 1992 and 2010 with available serum were classified into two groups: group 1 (control group, n=66) normal aminotransferases 2 (n=14) persistently increased histological features chronic hepatitis. Patients tested for RNA by reverse transcription-polymerase chain...
Torque Teno virus (TTV) is a ubiquitous infectious agent. Transplant recipients are at risk of hepatitis E (HEV) infection and could be vulnerable to TTV-associated adverse effects. The aim this study was evaluate the influence immunosuppression HEV on TTV replication liver injury in pediatric patients after orthotopic transplantation (OLT). Pediatric transplants were classified into following 2 groups: (1) those with normal serum aminotransferases levels (2) persistently increased...
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a glycolytic enzyme that also functions in transcriptional regulation, oxidative stress, vesicular trafficking, and apoptosis. Because GAPDH required for the insertion of cellular heme into inducible nitric oxide synthase [Chakravarti, R., et al. (2010) Proc. Natl. Acad. Sci. U.S.A. 107, 18004–18009], we extensively characterized binding properties GAPDH. Substoichiometric amounts ferric bound to (one per tetramer) form low-spin complex...
Objectives: In January 2004, an increase in gastrointestinal illness following oyster consumption was reported British Columbia. An investigation initiated to explore the association between norovirus infection and of Columbia oysters identify source contamination. Methods: The outbreak included active surveillance for human cases, two cohort studies, trace-back oysters, laboratory testing stools. Results: Enhanced identified 26 confirmed 53 clinical cases over 3 months. Oyster associated...
The aim of this study was to compare the performance four TaqMan RT-PCR assays with a commonly used nested and include Feline calicivirus (FCV) as an internal control.RNA extracted from 87 swine faecal samples 103 blood subjected different detection systems. Faecal naturally contaminated Hepatitis E virus (HEV) negative were artificially inoculated 3.2 x 10(3) PFU FCV. Detection results obtained on plasma 35.6% 4.9% assay, 8.0% 0%, 0% 13.8% 36.8% 3.9% systems A, B, C D respectively. Ct means...
Surface waters from paired agricultural watersheds under controlled tile drainage (CTD) and uncontrolled (UCTD) were monitored over 7 years in order to determine if there was an effect of CTD (imposed during the growing season) on occurrences loadings bacterial viral pathogens, coliphages, microbial source tracking markers. There significantly lower human, ruminant, livestock (ruminant plus pig) Bacteroidales markers watershed relation UCTD watershed. As for Salmonella spp. Arcobacter no...
Over 1,400 water samples were collected biweekly over 6 years from an intermittent stream protected and unprotected pasturing cattle. The monitored for host-specific Bacteroidales markers, Cryptosporidium species/genotypes, viruses coliphages associated with humans or animals, bacterial zoonotic pathogens. Ruminant markers did not increase within the restricted cattle access reach of stream, whereas ruminant marker increased significantly in unrestricted reach. Human downstream homes where...
In this study, the plasminogen-binding activity of Streptococcus suis serotype 2 was investigated. Bound human plasminogen activated by purified streptokinase, urokinase, or dysgalactiae subsp. equisimilis culture supernatant. Both and porcine were bound S. suis. Binding inhibited epsilon-aminocaproic acid, receptor heat sodium dodecyl sulfate resistant. One receptors identified as glyceraldehyde-3-phosphate dehydrogenase. suis-associated plasmin capable activating free plasminogen, which in...