Wenjie Zhao

ORCID: 0000-0003-4690-5609
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Research Areas
  • Ginseng Biological Effects and Applications
  • Microfluidic and Bio-sensing Technologies
  • Photosynthetic Processes and Mechanisms
  • Pharmacological Effects of Natural Compounds
  • Marine Biology and Environmental Chemistry
  • 3D Printing in Biomedical Research
  • Spectroscopy and Chemometric Analyses
  • Spectroscopy and Quantum Chemical Studies
  • Microbial Inactivation Methods
  • Photoreceptor and optogenetics research
  • Extracellular vesicles in disease
  • Lignin and Wood Chemistry
  • Magnesium Oxide Properties and Applications
  • Force Microscopy Techniques and Applications
  • Advanced Photocatalysis Techniques
  • Anodic Oxide Films and Nanostructures
  • Phagocytosis and Immune Regulation
  • Immune cells in cancer
  • Layered Double Hydroxides Synthesis and Applications
  • Pancreatic function and diabetes
  • Nanowire Synthesis and Applications
  • Materials Engineering and Processing
  • Hydrogels: synthesis, properties, applications
  • Landslides and related hazards
  • Electrical Contact Performance and Analysis

Chinese Academy of Sciences
2008-2025

Jilin University
2012-2025

Model Animal Research Center
2025

Nanchang University
2024-2025

Shanghai Institute of Materia Medica
2025

Ningbo Institute of Industrial Technology
2024-2025

Qingdao University of Science and Technology
2020-2025

Dalian Maritime University
2024

Yanbian University
2024

First Hospital of Jilin University
2024

Abstract Exosomes are highly important in clinical diagnosis due to their high homology with parental cells. However, conventional exosome detection methods still face the challenges of expensive equipment, low sensitivity, and complex procedures. Field effect transistors (FETs) not only most essential electronic component modern microelectronics industry but also show great potential for biomolecule owing advantages rapid response, label-free detection. In this study, we proposed a Si...

10.1038/s41378-022-00387-x article EN cc-by Microsystems & Nanoengineering 2022-05-30

A microsphere mediated exosome isolation and ultra-sensitive detection ExoDEP-chip was developed. limit of 193 exosomes per mL obtained by dispersing PS microspheres into microwells to reduce the fluorescence interference.

10.1039/d1an01061a article EN The Analyst 2021-01-01

CD47 is a ligand of SIRPα, an inhibitory receptor expressed by macrophages, dendritic cells, and natural killer (NK) and, therefore, transgenic overexpression considered effective approach to inhibiting transplant rejection. However, the detrimental effect signaling overlooked when exploring this approach. Here, we construct mutant replacing transmembrane intracellular domains with membrane anchor (CD47-IgV). In both human mouse CD47-IgV efficiently on cell surface protects against...

10.1016/j.xcrm.2024.101450 article EN cc-by Cell Reports Medicine 2024-03-01

The landslide hazard assessment plays a crucial role in risk mitigation and land use planning. result of corrected by surface deformation, obtained through time-series InSAR, has usually proven to have good application capabilities. However, the issue lies uncertainty InSAR results, where some deformations cannot be calculated, are not true deformations. This results will lead errors assessment. Here, we attempt evaluate hazards considering combined rainfall deformation. main objective this...

10.3390/rs16091587 article EN cc-by Remote Sensing 2024-04-29

Abstract Surface coatings are designed to mitigate pervasive biofouling herald, a new era of surface protection in complex biological environments. However, existing strategies plagued by persistent and recurrent biofilm attachment, despite the use bactericidal agents. Herein, chiral metal–organic framework (MOF)‐based coating with conformal microstructures enable anti‐biofouling mode that involves spontaneous disassembly followed bacterial eradication is developed. A facile universal...

10.1002/adma.202407409 article EN Advanced Materials 2024-09-05

Inspired by the mimic of dual charge separation in natural photosynthesis systems for biosolar cells (BSCs) applications where extraction at interface was insufficient, we report chlorophyll (Chl)-based trilayer cascade BSCs composed Chl-C1 and/or a Chl-C2 (Chl-C)-sensitized mesoporous TiO2 layer (TiO2–Chl-C) acting as electron layers well active to simulate primary acceptor and two additional Chl derivatives (Chl-A/Chl-D) mimicking reaction centers photosystems I II Z-scheme process...

10.1021/acsenergylett.8b02279 article EN ACS Energy Letters 2019-01-02

Thrombospondin-1 (TSP-1)/CD47 signaling induces cell death and inhibits angiogenesis. Here, we investigated the possibility of improving donor engraftment by blocking TSP-1/CD47 pathway in mouse models total body irradiation (TBI)-conditioned syngeneic hematopoietic stem transplantation (HSCT). Our findings revealed that HSCT was improved mice deficient CD47 (Cd47 -/- ) or TSP-1 (Thbs1 compared to wild-type (WT) mice. The lack enhanced production CXCL12 megakaryocytes platelets, promoting...

10.1016/j.isci.2025.111952 article EN cc-by-nc iScience 2025-02-05

Artificial liquid‐repellent surfaces are highly desirable to combat pervasive biofouling and corrosion in biological environments. However, existing strategies often suffer from slow binding kinetics harsh fabrication conditions, hindering the concurrent integration of liquid repellency, universal adhesion, robust flexibility. Herein, we report that it is possible engineer microbial biofilms as eco‐friendly, cohesive, flexible materials for omniphobic slippery coatings fulfilling all these...

10.1002/ange.202503295 article EN Angewandte Chemie 2025-04-07

Artificial liquid‐repellent surfaces are highly desirable to combat pervasive biofouling and corrosion in biological environments. However, existing strategies often suffer from slow binding kinetics harsh fabrication conditions, hindering the concurrent integration of liquid repellency, universal adhesion, robust flexibility. Herein, we report that it is possible engineer microbial biofilms as eco‐friendly, cohesive, flexible materials for omniphobic slippery coatings fulfilling all these...

10.1002/anie.202503295 article EN Angewandte Chemie International Edition 2025-04-07

Among the various methods for recovering lignin from black liquor, membrane separation has gained prominence in paper industry due to its advantages of uniform molecular weight distribution, high recovery rates, and absence secondary pollution. However, over time, particles tend deposit form a cake layer on surface, leading fouling decline filtration flux. To address this issue, study investigates construction ceramic membranes with radial rib patterns, examines effects different...

10.3390/polym17101424 article EN Polymers 2025-05-21

Objective: To investigate the protective effects of varespladib against Naja atra-induced acute liver injury (ALI) and to elucidate toxic mechanism snake venom phospholipase A2 (SVPLA2)-induced hepatic oxidative stress, with a particular focus on role Nrf2 signaling its downstream pathways.Methods: A combination in vivo vitro models N. atra envenomation was employed assess injury, mitochondrial dysfunction. The interaction between SVPLA2 analyzed, treatment these processes were evaluated...

10.1080/13510002.2025.2507557 article EN cc-by-nc Redox Report 2025-05-21

Rock slopes are widely distributed in China's strong seismic areas, and due to the wide distribution of areas China frequent activities, there is an urgent need carry out scientific research on dynamic response slopes. This paper aims use discrete element method simulate three different earthquake waves a simplified model analyse evaluate results based visual images obtained from experiment. The show that maximum displacement concentrated at bottom slope model, indicating most vulnerable...

10.54097/7j9fmn60 article EN Highlights in Science Engineering and Technology 2025-05-23

10.1016/j.jep.2012.10.007 article EN Journal of Ethnopharmacology 2012-10-17
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