A5050465137- Iron Metabolism and Disorders
- Hemoglobinopathies and Related Disorders
- Child Nutrition and Water Access
- HER2/EGFR in Cancer Research
- Dietary Effects on Health
- Blood groups and transfusion
- Healthcare Systems and Reforms
- Obesity, Physical Activity, Diet
- Nutritional Studies and Diet
- Advanced Breast Cancer Therapies
- Breast Cancer Treatment Studies
Abdelmalek Essaâdi University
2016-2024
Triple Negative Breast Cancer (TNBC) is defined by a lack of estrogen and progesterone receptor gene expression the absence overexpression on HER2. It associated to poor prognosis. We propose analyze clinicopathologic prognostic characteristics this breast cancer subtype in Mediterranean population originated or resident North Morocco. conducted retrospective study 279 patients diagnosed with between January 2010 2015. Clinicopathologic features have been analyzed. Disease-Free Survival...
Unlike the other hemoglobinopathies, few researches have been published concerning α-thalassemia in Morocco. The epidemiological features and mutation spectrum of this disease are still unknown. This regional newborn screening is first to study north During period from January 2015 December 2016, 1658 newborns umbilical blood samples were investigated. Suspected screened for α-globin defects using Gap-PCR Multiplex Ligation-dependent Probe Amplification technique. prevalence α-thalassemia,...
Consanguinity is a social behavior characterized by the arrangement of marriages between relatives. It coincides generally with geographic distribution recessive genetic diseases as it increases likelihood homozygosis and, consequently, incidence their pathologies in population. In this pilot study, we assess effect inbreeding on burden hemoglobinopathies Northern Morocco. From January 2016 to December 2018, 197 children born studied region three ancestral generations and diagnosed were...
Sickle cell disease is one of the most common severe monogenic disorders in world. The –158 XmnI polymorphism (C>T) Gγ-globin gene promoter known to be associated with increased expression gene, thus, higher production Hb F and lesser clinical severity. This study aims determine frequency its association levels as a modulating factor sickle severity north Moroccan patients. Three hundred eight subjects carrying mutation 160 healthy individuals were recruited at regional hospital Larache,...
The present study investigated the impact of COVID-19 pandemic on dietary habits. Data were collected from an online survey (n = 171, out 315 initial respondents) during lockdown period April to June 2020. questionnaire was provided in Arabic, French, and English language divided into five sections: sociodemographic socioeconomic information, eating motivations, food consumption frequency, food-related behaviors, purchase priorities. results showed that health pleasure primary perceived...
Abstract Background: Hemoglobinopathies are the most frequent widely spread genetic disorders. In Morocco, epidemiological and clinical data scarce. The present study aims to determine spectrum geographic distribution of hemoglobinopathies in Larache province, North Morocco. Methods: A retrospective cross-sectional was conducted from January 2015 December 2018 at provincial hospital city. All patients’ records having a hemoglobinopathy were analyzed. Background (age, gender, origin) each...