A5065356566- Neurological disorders and treatments
- Genetic Neurodegenerative Diseases
- Glycogen Storage Diseases and Myoclonus
- Neurological and metabolic disorders
- Child Abuse and Related Trauma
- Ophthalmology and Eye Disorders
- Noise Effects and Management
- Neuroethics, Human Enhancement, Biomedical Innovations
- Functional Brain Connectivity Studies
- Cardiovascular Syncope and Autonomic Disorders
- Free Will and Agency
- Metal complexes synthesis and properties
- Advanced MRI Techniques and Applications
- Metal-Catalyzed Oxygenation Mechanisms
- RNA modifications and cancer
- Parkinson's Disease Mechanisms and Treatments
- Delphi Technique in Research
University of Nebraska Medical Center
2017-2024
St. Luke's Clinic
2020
National Institutes of Health
2012
National Cancer Institute
2012
Triple-negative breast cancer (TNBC) is an aggressive subtype of that diagnosed in approximately 15% all human (BrCa) patients. Currently, no targeted therapies exist for this BrCa and prognosis remains poor. Our laboratory has previously identified a proliferation/DNA repair/cell cycle gene signature (Tag signature) characteristic TNBC. We hypothesize targeting the dysregulated biological networks Tag will lead to identification improved combination TNBC.Cross-species genomic analysis was...
<strong>Background:</strong> The exact pathophysiology of primary Orthostatic Tremor (OT) is unknown. A central oscillator assumed, and previous imaging studies show involvement cerebellar pathways. However, the presence ataxia on clinical exam disputed. We set out to study in OT prospectively. <strong>Methods:</strong> EMG-confirmed subjects spousal controls received a neurological with additional semiquantitative evaluations as part multinational, prospective study. These included detailed...
Non-ketotic hyperglycaemia (NKH) is the most common metabolic cause of hemichorea-hemiballismus (HC-HB) and an often-reversible condition. A 68-year-old man presented to emergency department with a severe hyperglycaemic episode altered mental status. He was treated appropriately discharged home after his blood glucose levels were normal improvement Four weeks discharge, he returned flailing movements bilateral upper lower limbs. MRI brain revealed hyperintensities putamen on T1-weighted...
Orthostatic tremor is a rare movement disorder characterized by sensation of unsteadiness and leg while standing. It has been hypothesized that the attributable to dysregulation central oscillatory network in brain. This putative includes primary motor cortex, supplementary area, cerebellum, thalamus, pontine tegmentum. We studied this brain recording resting-state functional MRI data from individuals with orthostatic tremor. For each participant, we measured connectivity using seed-based...
Tuesday, April 28April 14, 2020Free AccessAre balance scales affected by fear of falling? – a Delphi methodology study (1583)Diego Torres-Russotto, James Shou, Nabeel Syed, Venkata Bendi, Lori Schmaderer, Jennifer McKune, Amy Hellman, … Show All , Luis Zayas, Rebecca Thompson, Pamela May, Ryan Brennan, John Bertoni, Dawn Venema, Joseph Siu, Vivien Marmelat, and Danish Bhatti FewerAuthors Info & AffiliationsApril 2020 issue94 (15_supplement)https://doi.org/10.1212/WNL.94.15_supplement.1583...