Osamu Maeda

ORCID: 0000-0003-4700-6541
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About
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Research Areas
  • Gastric Cancer Management and Outcomes
  • Gastrointestinal Tumor Research and Treatment
  • Inflammatory Bowel Disease
  • Helicobacter pylori-related gastroenterology studies
  • Gastrointestinal disorders and treatments
  • Pancreatic and Hepatic Oncology Research
  • Prostate Cancer Treatment and Research
  • Cancer Immunotherapy and Biomarkers
  • Esophageal Cancer Research and Treatment
  • Microscopic Colitis
  • Renal cell carcinoma treatment
  • Bladder and Urothelial Cancer Treatments
  • Colorectal Cancer Treatments and Studies
  • Metastasis and carcinoma case studies
  • Semiconductor Quantum Structures and Devices
  • Eosinophilic Esophagitis
  • Multiple and Secondary Primary Cancers
  • Gastrointestinal Bleeding Diagnosis and Treatment
  • Colorectal Cancer Screening and Detection
  • Urinary and Genital Oncology Studies
  • Testicular diseases and treatments
  • Prostate Cancer Diagnosis and Treatment
  • Neuroblastoma Research and Treatments
  • Urological Disorders and Treatments
  • Genetic factors in colorectal cancer

Nagoya University Hospital
2016-2025

Nagoya University
2013-2023

Hudson Institute
2022

University of Tsukuba
2022

Nagoya City University Hospital
2021

Kyoto University
2019

Chugai Pharma (United States)
2017

Sanofi (France)
2017

Yakult (Netherlands)
2017

Takeda (Japan)
2017

Objective: Given the frequent adverse events with multidrug chemotherapy, not only survival benefit but also feasibility of using neoadjuvant chemotherapy to treat pancreatic cancer need be clarified. Summary Background Data: Although development regimens has improved outcomes patients unresectable cancer, benefits these treatments in neo-adjuvant setting remain controversial. Methods: Patients borderline-resectable were enrolled and randomly assigned receive either FOLFIRINOX or gemcitabine...

10.1097/sla.0000000000005430 article EN Annals of Surgery 2022-03-03

Abstract BACKGROUND: In colorectal cancer (CRC), DNA methylation anomalies define distinct subgroups termed CpG island methylator phenotype 1 (CIMP1), CIMP2, and CIMP‐negative. The role of this classification in predicting recurrence disease‐free survival (DFS) resected stage III CRC was evaluated. METHODS: Sporadic cancers from 161 patients were analyzed. Bisulfite pyrosequencing used to examine the 2 global markers (LINE‐1, Alu) 9 loci ( MINT1, MINT2, MINT31, P16, hMLH1, P14, SFRP1 ,...

10.1002/cncr.25737 article EN Cancer 2010-11-18

The distal esophagus harbors a complex bacterial population. We hypothesized that better understanding of communities in the would facilitate role bacteria esophageal disease. Here, we investigated composition subjects with normal esophagus, reflux esophagitis, and Barrett's esophagus.Two biopsy specimens were obtained from at 1 cm above gastroesophageal junction under endoscopic examination 18 patients (6 each esophagus) used for histological DNA extraction. Fragments 16S rDNA genes...

10.1186/1471-2334-13-130 article EN cc-by BMC Infectious Diseases 2013-03-11

Helicobacter pylori infection is a risk factor for gastric carcinogenesis. High dietary vitamin C intake appears to protect against carcinoma. It has been suggested that exerts the protective effect by scavenging free radicals may be enhanced H. pylori. However, not investigated in relation direct action on In this study, authors attempted clarify possibility both vitro and vivo.Susceptibility testing of (64 strains) was performed agar dilution method. Bactericidal actions were determined...

10.1002/(sici)1097-0142(19971115)80:10<1897::aid-cncr4>3.0.co;2-l article EN Cancer 1997-11-15

Background and study aims: Advances in endoscopy have led to imaging of the details gastric mucosa, but histological diagnosis usually has be confirmed by endoscopic biopsy. A method confocal endomicroscopy that recently been developed allows observation living cells vivo. Several investigators reported technique is value, there as yet no studies describing its application cancer. Patients methods: Twenty-seven patients with early cancer underwent (Pentax EG-3870CIK; Pentax, Tokyo, Japan)....

10.1055/s-2006-944855 article EN Endoscopy 2006-11-17

BackgroundTo investigate the optimal treatment of locally advanced prostate cancer, a prospective randomized trial was conducted to compare radical prostatectomy plus endocrine therapy versus external beam radiotherapy therapy.

10.1093/jjco/hyl115 article EN Japanese Journal of Clinical Oncology 2006-11-02

Transvaginal Doppler ultrasound with color flow imaging is a new technique for the evaluation of gynecologic diseases. This method was used diagnosis ovarian tumors in 24 women treated Department Obstetrics and Gynecology, Nagoya University Hospital, Japan. Waveforms parenchymal tumor arteries or surface were compared using values pulsatility index (PI). The value 1/PI 0.69 +/- 0.05 benign 1.87 0.65 malignant (P less than .01). When cutoff set at 0.8 (cutoff PI 1.25), accuracy 95.8% (23 24)....

10.1177/875647939200800336 article EN Journal of diagnostic medical sonography 1992-05-01

In Japan, screening examination with photofluorography is widely performed to reduce the mortality due gastric cancer. The possibility of a future decline in cancer cases and changes its characteristics suggested. aim this study was examine usefulness direct radiology as general health technique historical Japan.This involved 936 patients whose carcinomas were detected by part at Aichi Prefectural Center for Health Care from 1970 2000. We studied prevalence carcinoma, prognosis, differences...

10.1111/j.1440-1746.2007.04991.x article EN Journal of Gastroenterology and Hepatology 2007-06-16

Abstract The growth of phytoplankton in an ice‐covered lake was investigated with special reference to their photosynthetic and heterotrophic activities. Under transparent ice the production organic matter maintained enough hold a high density phytoplankton. When light penetration water diminished strongly by ice‐sheet, heterotrophy contributed largely

10.1002/iroh.19730580507 article EN Internationale Revue der gesamten Hydrobiologie und Hydrographie 1973-01-01

10.1016/j.ijmachtools.2004.08.021 article EN International Journal of Machine Tools and Manufacture 2004-10-07

Abstract Background: Confocal endomicroscopy is a new technology that provides microscopic images of cellular morphology in the gastrointestinal tract vivo . In particular, confocal microendoscopy allows histological diagnosis during endoscopic examination. We examined patients with ulcerative colitis (UC) using endoscopy and investigated features endomicroscopic inflamed non‐inflamed rectal mucosa. Methods: Seventeen UC, 12 active phase 5 non‐active phase, 14 non‐UC control who had colon...

10.1111/j.1440-1746.2008.05559.x article EN Journal of Gastroenterology and Hepatology 2008-12-01
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