Two bisdihydroanthracenone atropodiastereomeric pairs, including homodimeric flavomannin A (1) and the previously unreported B (2), two new unsymmetrical dimers (3 4), mixed dihydroanthracenone/anthraquinone (5 6) were isolated from Talaromyces wortmannii, an endophyte of Aloe vera. The structures 2–6 elucidated by extensive NMR mass spectrometric analyses. axial chirality biaryls was determined using TDDFT ECD VCD calculations, combination which however did not allow assignment central...

Nudibranchia, marine soft-bodied organisms, developed, due to the absence of a protective shell, different strategies protect themselves against putative predators and fouling organisms. One strategy is use chemical weapons distract predators, as well pathogenic microorganisms. Hence, these gastropods take advantage incorporation molecules. Thereby original source natural products varies; it might be food source, de novo synthesis from sea slug, or biosynthesis by associated bacteria. These...

Bunaken National Park has been surveyed for a fourth time in 14 years, an attempt to establish the species composition of heterobranch sea slugs baseline study monitoring programs and protection this special park. These molluscs are potentially good indicators health ecosystem, as many species-specific predators on huge variety marine benthic sessile invertebrates from almost every taxonomic group. Additionally, they known contain bio-compounds significance pharmaceutical industry. It is...

Bunaken National Park (BNP) is one of the most famous marine national parks in Indonesia with an extraordinary diversity life forms. However, this threatened by increasing population on islands, ongoing destructive fishing techniques and lately increase tourism. Protecting managing future use BNP resources will require assessment both, local biodiversity through monitoring efforts identification subsequent reduction any threats or changes park. A high Heterobranchia indicates a metazoan...

Endofit dapat diartikan sebagai mikroba yang hidup berkoloni dalam jaringan internal tumbuhan tanpa menyebabkan efek merugikan secara langsung pada tersebut. Organisme endofitik memiliki potensi sangat besar untuk dieksploitasi dan menghasilkan produk alami baru bermanfaat di bidang kedokteran, pertanian, industri. Pada sisi lain kebutuhan terhadap obat-obatan membantu umat manusia melawan pelbagai penyakit tidak pernah berhenti, hal ini disebabkan adanya resistensi bakteri, infeksi virus,...

We describe a new species, Moridilla jobeli sp. nov., belonging to the marine heterobranch group Aeolidioidea. Up now, it is only recorded from Bunaken National Park, North Sulawesi, Indonesia. A combination of histological, computer tomographic and scanning electron microscopic methods was applied in order illustrate anatomy nov. detail. Furthermore, we conducted molecular analyses which include available partial COI 16S rRNA sequences, as well nuclear gene Histone 3 (H3) Facelinidae...

Abstract. Sondak CFA, Kaligis EY, Bara RA. 2019. Economic valuation of Lansa Mangrove Forest, North Sulawesi, Indonesia. Biodiversitas 20: 978-986. forest gives many benefits and services to human environment. Even though it contributes services, coastal ecosystems threatened as one the most critical in world. The study aims estimate economic value ecosystem provided by mangrove forest, Wori Sub-district, Minahasa District, Sulawesi Province, Here, we describe use (direct indirect value)...

Investigations on the biochemical relationship between Doriprismatica stellata (Chromodorididae, Doridoidea) nudibranchs, their egg ribbons, and associated dietary sponge Spongia cf. agaricina (Demospongiae, Porifera) led to isolation of structurally new scalarane-type sesterterpene 12-deacetoxy-4-demethyl-11,24-diacetoxy-3,4-methylenedeoxoscalarin, with an unprecedented position cyclopropane ring annelated A. Unlike other scalaranes, which are most often functionalized at C-12 C, it bears...

Abstract As coral reef communities change and reorganise in response to increasing disturbances, there is a growing need for understanding species regimes their contribution ecosystem processes. Using case study on reefs at the epicentre of tropical marine biodiversity (North Sulawesi, Indonesia), we explored how application different approaches (i.e., use major taxonomic categories, high resolution categories trait-based approaches) affects detection distinct fish benthic communities. Our...

Abstract Members of the widely distributed and common nudibranch family Phyllidiidae are often easily spotted in marine environment because their conspicuous colours obvious presence on reef. They interesting with regard to defensive chemical compounds that may lead new drug discoveries. Despite abundance, is also well known for its taxonomic problems difficulties species identification due very similarly coloured lack morphological characters. In this study, phyllidiid were analysed using...

Abstract: Endophytic fungi is a species of which lives within plant tissues including leaf’s that also harmless for the host itself. Isolates endophytic have potent antibacterial capability with broad spectrum. The aim this research to know whether there an effect isolated from Avicennia marina leaf towards Staphylococcus aureus and Shigella dysenteriae. method used activity test, done by putting mycelia in combination media has been smeared Based on done, it obtained two types mangrove...

Ascidian adalah avertebrata laut yang diketahui memproduksi senyawa bioaktif seperti antibakteri. Tujuan dari penelitian ini untuk mengetahui efektiviitas fraksi n-heksana, metanol, dan air ekstrak etanolik ascidian Lissoclinum sp. sebagai antibakteri terhadap 2 spesies bakteri Gram positif Staphylococus saprophyticus Bacillus megaterium serta negatif yaitu Pseudomonas aeruginosa Escherechia coli. Ekstraksi diawali dengan Maserasi sampel menggunakan etanol 95% selama tiga kali kemudian...

Abstract: Callyspongia sp. is one of the kinds sea sponge which hardly used instead its potential in order to be as antibacterial, anticancer, and also antifungi.The objective research observe effect antibacterial endosymbiont fungi Pseudomonas aeruginosa Ecshericia coli. Method: Method chosen test by pasting myselia on subject. The result combination, then, observed a measure zone resistance effect. Result: observation presents two fungi, isolated from Callyspongia; Black Myselium Fungi...

Mangrove merupakan jenis tumbuhan yang memiliki kemampuan biofilter, yaitu untuk menyaring, mengikat dan memerangkap polusi di alam bebas atau biasa disebut sebagai Tumbuhan Hiperakumulator. Kemampuan berupa kelebihan sedimen, limbah buangan rumah tangga menyimpan logam berat pada akar, batang daunnya berperan penting membantu dalam menetralisir masuknya sumber pencemar seperti timbal (Pb) masuk ke perairan meningkatkan kualitas air. Tujuan dari penelitian ini adalah mengetahui daya serap...

Chemical investigation of the endophytic fungus Botryosphaeria australis isolated from Avicennia marina originally Hainan Province, P.R. China, yielded a new compound botryosphaenin (1), class napthoquinone, together with 5 known compounds, botryosterpene (2) and 5-hydroxy-2,7-dimethoxynaphthalene-1,4-dione (3) its derivatives, 6-ethyl-5-hydroxy-2,7-dimethoxynaphthalene-1,4-dione (4), O-methylaspmenone (5), O-methylasparvenone (6) 5-(carboxymethyl)-7-hydroxy-1,4a-dimethyl-6-methylene...

Abstract: Mangrove has been known long to have many benefits. One of the mangrove species that believed antimicrobial effects is Sonneratia alba. The objective study was evaluate any antibacterial effect endophytic fungi isolated from roots alba toward growth Staphylococcus aureus and Eschericiae coli, using combination method PDA (Potato Dextrose Agar) NA (Nutrient Agar). From result we found two types endophytes. Black white colored fungus obtained roots. Both inhibit coli bacterial...

Abstract: Srikaya leaf contains terpenoid, polyphenol, alkaloid, and flavonoid that can potentially be an antibacterial. This study was aimed to obtain the potency of srikaya extract against Staphylococcus aureus (ATCC25923) Escherichia coli (ATCC11229). experimental laboratory using Kirby-Bauer modified well diffusion technique in Phytochemistry Microbiology Laboratory MIPA Faculty at Sam Ratulangi University. obtained by ethanol maceration technique. The concentrations were as follows:...

Spons merupakan salah satu biota laut penyusun terumbu karang. Hewan ini diketahui mengandung senyawa-senyawa yang berpotensi untuk dikembangkan dalam bidang pengobatan, diantaranya sebagai antibakteri. Penelitian bertujuan mengetahui potensi antibakteri dan melakukan pengujian aktivitas dari spons Dictyonella funicularis Phyllospongia lamellosa diambil perairan Bunaken, Sulawesi Utara. Hasil penelitian menunjukkan bahwa ekstrak memiliki Ekstrak menghasilkan lebih tinggi dibandingkan obat

Abstract: Endophytic fungi could be used as an alternative antibiotic because it produced bioactive compounds, which are developed basic ingredients for medicine such antibiotic, antioxcide, anticancer. can isolated from Rhizome of Alpinia galanga L. is abundant in Indonesia. The aim this study was to find the inhibiting zone endophytic rhizome growth Staphylococcus aueus and Escherichia coli. This experimental laboratory using modified Kirby-Bauer well diffusion technique Marine...

Title (Bahasa Indonesia): Senyawa antibakteri spons, Agelas tubulata dan Phyllospongia sp., dari Perairan Teluk Manado, terhadap pertumbuhan beberapa strain bakteri tubulataand Phyllospongiasp. are marine spongethat contain active compoundsthat have potential to beantibacterial, anticancer and antifungal which not been used. This study was aimed examine the sponge extracts inhibitbacterial growth, i.e. Pseudomonas aeruginosa, Proteus mirabilis, Staphylococcus aureus, Escherichia coli, S....

Abstract: Ginger rhizome contains antimicrobial compounds of phenol group, flavonoids, terpenoids, and aetheric oil. Endophytic fungi are commonly found in ginger plant Zingiber officinale Rosc. which is widely available Indonesia. There a symbiosis between these endophytic its host plants form genetic material transform, thus could produce the same active as does, or at least involved host’s biosynthetic pathway. This study was aimed to determine inhibitory effect isolated from (Zingiber...