A5067593994- Blood transfusion and management
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Pancreatic and Hepatic Oncology Research
- Cancer, Hypoxia, and Metabolism
- Intestinal Malrotation and Obstruction Disorders
- Clinical Nutrition and Gastroenterology
- Blood donation and transfusion practices
- Pancreatitis Pathology and Treatment
- Gallbladder and Bile Duct Disorders
- Lymphatic System and Diseases
- Child Nutrition and Feeding Issues
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Immunotherapy and Immune Responses
- Abdominal Trauma and Injuries
- Botulinum Toxin and Related Neurological Disorders
- Virus-based gene therapy research
- Clinical Laboratory Practices and Quality Control
- Colorectal Cancer Surgical Treatments
- Breast Implant and Reconstruction
- Cancer Immunotherapy and Biomarkers
- Palliative Care and End-of-Life Issues
- Cardiac and Coronary Surgery Techniques
- Advances in Oncology and Radiotherapy
- Cancer survivorship and care
- Appendicitis Diagnosis and Management
Center for Cancer and Blood Disorders
2023
Ottawa Hospital Research Institute
2018-2022
Ottawa Hospital
2017-2022
University of Ottawa
2016-2022
Emory University
2019
Johns Hopkins University
2016
McGill University
2013-2015
Surgical stress results in a significant reduction natural killer (NK) cell cytotoxicity (NKC), which has been linked to postoperative cancer metastases. However, few studies have measured the impact of surgical upon NK IFNγ secretion (NKA), cytokine with essential roles controlling infection and The objective this study was investigate on NKA colorectal (CRC) surgery patients.Peripheral blood collected from CRC patients (n = 42) preoperatively day (POD) 1, 3, 5, 28, 56. Healthy donor 27)...
The Focused Assessment with Sonography for Trauma examination is an invaluable tool in the initial assessment of any injured patient. Although highly sensitive and accurate identifying hemoperitoneum, occasional false negative results do occur select scenarios. We present a previously unreported case survival following blunt cardiac rupture associated pericardial window due to concurrent wall laceration. A healthy 46-year-old white woman presented our level 1 trauma center hemodynamic...
A significant proportion of red blood cell (RBC) transfusions are administered intraoperatively; yet there is limited evidence to guide transfusion decisions in this setting. The objective systematic review explore the availability, quality and content clinical practice guidelines (CPGs) reporting on indication for allogenic RBC during surgery.Major electronic databases (MEDLINE, EMBASE CINAHL), guideline clearinghouses Google Scholar, will be systematically searched from inception January...
Compensatory hypertrophy of muscle fibers occurs when tension on a skeletal is increased. We looked for this phenomenon in response to strabismus surgery by performing large right lateral rectus resection 16 rats. Muscle fiber diameters all horizontal muscles were measured at 2-week postoperative intervals. Significant occurred both the antagonist medial and resected within 4 weeks. Fiber diameter subsequently returned baseline muscles. postulate that setting may be compensatory increased...
Abstract Background Major liver resection is associated with blood loss and transfusion. Observational data suggest that hypovolaemic phlebotomy can reduce these risks. This feasibility RCT compared the standard of care, to inform a future multicentre trial. Methods Patients undergoing major resections were enrolled between June 2016 January 2018. Randomization was done during surgery surgeons blinded group allocation. For phlebotomy, 7–10 ml per kg whole removed, without intravenous fluid...
A 79-year-old male presented with abdominal pain, incidental umbilical hernia and acute midgut volvulus that was not detected until surgical exploration. When he to hospital, computed tomography (CT) findings indicated perforated jejunoileal diverticulitis; however, in the operating room clockwise volvulization of jejunum ileum, secondarily inflamed diverticula, incomplete malrotation (right-sided duodenojejunal flexure), right retroperitoneal adhesions (Ladd's bands) numerous other...
Clinically relevant postoperative pancreatic fistula (CR-POPF) is the most common cause of major morbidity following resection. Intra-abdominal drains are frequently positioned adjacent to anastomosis or transection margin at time surgery aid in detection and management CR-POPF. Drains can either evacuate fluid by passive gravity (PG) be attached a closed suction (CS) system using negative pressure. There controversy as whether one these two systems superior. The objective this review...