- Cardiac, Anesthesia and Surgical Outcomes
- Lung Cancer Diagnosis and Treatment
- Esophageal and GI Pathology
- Esophageal Cancer Research and Treatment
- Medical Malpractice and Liability Issues
- Patient Safety and Medication Errors
- COVID-19 and healthcare impacts
- Advances in Oncology and Radiotherapy
- Palliative Care and End-of-Life Issues
- Hip and Femur Fractures
- Cancer Diagnosis and Treatment
- Enhanced Recovery After Surgery
- Head and Neck Cancer Studies
- Cardiac Arrest and Resuscitation
- Health and Wellbeing Research
- Thyroid and Parathyroid Surgery
- Circadian rhythm and melatonin
- Empathy and Medical Education
- Dietary Effects on Health
- Metastasis and carcinoma case studies
- Ethics in medical practice
- Body Contouring and Surgery
- Nutrition and Health in Aging
- Cancer, Stress, Anesthesia, and Immune Response
- Venous Thromboembolism Diagnosis and Management
Ottawa Hospital
2014-2024
Ottawa Hospital Research Institute
2018-2024
University of Ottawa
2015-2022
Ottawa University
2021
Despite curative intent resection in patients with non-small cell lung cancer (NSCLC), recurrence leading to mortality remains too common. Melatonin has shown promise for the treatment of cancer; however, its effect following not been studied. We evaluated if melatonin taken after complete reduces and mortality, or impacts quality life (QOL), symptomatology immune function. Participants received (20 mg) placebo nightly one year surgical primary NSCLC. The outcome was two-year disease-free...
As an innovative approach to improve quality of surgical care, we combined surgeon self-assessment and anonymized peer comparison with continuous improvement seminars using positive deviance (CQI/PD) identify surgeon(s) the lowest rates adverse events (AEs) guide group practice recommendations. Our objective was quantify impact these interventions on postoperative AEs after major non-cardiac chest operations. All all thoracic operations (n = 1,084, March, 2013 February, 2016, single-center)...
Objectives Although spontaneous breathing trials (SBTs) are standard of care to extubation readiness, no tool exists that optimises prediction and standardises assessment. In this study, we evaluated the feasibility clinical impressions Extubation Advisor (EA), a comprehensive decision support (CDS) tool. Design Phase I mixed-methods observational study. Setting Two Canadian intensive units (ICUs). Participants We included patients on mechanical ventilation for ≥24 hours clinicians...
A time course analysis was undertaken to evaluate how perioperative process-of-care and outcome measures evolved after implementation of an enhanced recovery thoracic surgery (ERATS) program.Outcome were compared between patients undergoing major elective during a 9-month pre-ERATS period those at 1-3, 4-6, 7-9 months post-ERATS implementation. Outcome included length stay, the 30-day readmission rate, emergency department visits, minor adverse events. Process first activity, out-of-bed,...
Thoracic surgery carries significant risk of postoperative adverse events (AEs). Multiple international recording systems are used to define and collect AEs following thoracic procedures. We hypothesized that a simple-yet-ubiquitous approach AE documentation could be developed allow universal data entry into separate databases.AE definitions the Canadian Association Surgeons (CATS) system 4 databases were matched compared. This consisted reviewing definition each as described by their...
Postoperative adverse events (AEs) following pulmonary resection enormously impact patient well-being, length of stay (LOS) and healthcare costs. Standardised AE data collection can be used to identify positive outliers demonstrating deviance (PD) who may helpful inform the best practice. Here, we describe our initial experience a novel quality improvement process using PD reduce LOS AEs.AE rates were collected from four centres (2014-2020) common dictionary. Surgeons repeatedly participated...
Background: In this study, we investigate indocyanine green (ICG) dye visualization of the thoracic duct (TD) and conduit perfusion during esophagectomy to reduce anastomotic leak (AL) chylothorax adverse events (AEs). Methods: Retrospective data adult patients who underwent for esophageal carcinoma between July 2019 2022 were included (n = 105). ICG was delivered intravenously (2 mL, 2.5 mg/mL) assess into small bowel mesentery, inguinal lymph nodes, or foot web spaces TD using fluorescence...
Abstract Objective To compare the safety and effectiveness of different surgical approaches in thymectomy: robotics, subxiphoid, lateral video‐assisted thoracoscopy surgery (LVATS) open. Methodology We retrospectively reviewed 68 cases thymectomy with a robot‐assisted, LVATS, open sternotomy or thoracotomy approach for thymic lesions myasthenia gravis between July 2017 May 2023 at single centre. Peri‐operative outcomes (operating time, estimated blood loss, conversion rates, R0 resection,...
Abstract Background Surgical resection plays a central role in the multimodal curative intent management of esophageal cancer. Despite advances peri-operative care, 60% patients undergoing esophagectomy experience postoperative adverse events (AEs), if AEs are prospectively collected by surgeons. We recently performed systematic review documenting published index hospital costs AEs, yet overall Canadian centres remains unknown. Methods Between 2017–2021, data from 10 were included. Volumes...
Background We describe a novel process using positive deviance (PD) with the Canadian Association of Thoracic Surgeons members, to identify perioperative best practice minimise anastomotic leak (AL) and length stay (LOS) following oesophagectomy. To our knowledge, this is first National combination level 1 evidence expert opinion (ie, PD seminar) aimed at reducing AL LOS in oesophageal surgery. Our primary hypothesis that multicentre seminar feasible, could lead generation practices...
The prominence of "enhanced recovery after surgery" (ERAS) protocols being adopted in thoracic surgery requires a re-evaluation mechanical venous thromboembolism (VTE) prophylaxis guidelines. goal this study was to assess the role sequential compression devices (SCD) prevention VTEs such as deep vein thrombosis and pulmonary embolism (PE) surgical patients.We identified 200 patients who underwent elective oncological between December 2018 2020 2 cohorts-1 with SCDs 1 without (i.e. non-SCD)....