A5101639398- Cardiac, Anesthesia and Surgical Outcomes
- Lung Cancer Diagnosis and Treatment
- Pleural and Pulmonary Diseases
- Shoulder and Clavicle Injuries
- Shoulder Injury and Treatment
- Lung Cancer Treatments and Mutations
- Breast Cancer Treatment Studies
- Spine and Intervertebral Disc Pathology
- Occupational and environmental lung diseases
- Optical Coherence Tomography Applications
- SARS-CoV-2 and COVID-19 Research
- Medical Imaging and Analysis
- Atrial Fibrillation Management and Outcomes
- Trauma Management and Diagnosis
- Lung Cancer Research Studies
- Nerve Injury and Rehabilitation
- Pharmacological Effects and Toxicity Studies
- Pregnancy and Medication Impact
- Anesthesia and Pain Management
- Aortic aneurysm repair treatments
- Enhanced Recovery After Surgery
- Spinal Fractures and Fixation Techniques
- Ultrasound in Clinical Applications
- Reconstructive Surgery and Microvascular Techniques
- Advanced Breast Cancer Therapies
Ottawa Hospital
2016-2025
Ottawa Hospital Research Institute
2015-2024
Chinese University of Hong Kong
2024
University of Ottawa
2017-2024
Xian Yang Central Hospital
2024
Lanzhou University Second Hospital
2020-2023
Lanzhou University
2020-2023
Southwest University of Science and Technology
2023
Chinese PLA General Hospital
2013-2020
Chengdu Medical College
2020
Shoulder arthroplasty provides reliable pain relief and restoration of function. However, the effects fatty infiltration atrophy in supraspinatus infraspinatus muscles on functional outcomes are not well understood.The purposes this study were to (1) compare preoperative with postoperative after primary shoulder arthroplasty; (2) identify any associations between these variables outcome measures.A retrospective analysis was undertaken 62 patients a mean age 67 years (range, 34-90 years) who...
Despite curative intent resection in patients with non-small cell lung cancer (NSCLC), recurrence leading to mortality remains too common. Melatonin has shown promise for the treatment of cancer; however, its effect following not been studied. We evaluated if melatonin taken after complete reduces and mortality, or impacts quality life (QOL), symptomatology immune function. Participants received (20 mg) placebo nightly one year surgical primary NSCLC. The outcome was two-year disease-free...
Background: The long-term outcomes of single- versus double-row fixation in arthroscopic rotator cuff repair are not currently known. Purpose: To compare the treatment effects suture technique full-thickness tears at 10-year follow-up. Study Design: Randomized controlled trial; Level evidence, 1. Methods: Patients were evaluated 10 years postoperatively. primary outcome measure was Western Ontario Rotator Cuff Index (WORC). Secondary measures included American Shoulder and Elbow Surgeons...
Context. Many breast cancer survivors live with chronic neuropathic pain (CNP) after treatment. Despite pharmacological management of CNP, many women continue to report disabling and reduced quality life. Addressing psychosocial interventions as an adjunct treatment is often recommended for CNP. Objectives. The purpose this study was compare the effects group-delivered mindfulness-based stress reduction compared a waitlist control group among living Methods. A randomized controlled trial...
Background The Canadian Special Operations Forces Command conducts explosives operations and training which exposes members to explosive charges at close proximity. This 5‐year longitudinal trial was conducted in follow‐up our initial examined military breachers with MRI EEG pre post blast exposure. Purpose To examine brain findings personnel exposed multiple repeated exposures. Study Type Five‐year prospective trial. Population Ninety‐two males aged 23–42 an average of 9.4 years Field...
Purpose Many individuals with inborn errors of immunity (IEIs) have poor humoral immune (HI) vaccine responses. Only a few studies examined specific cell-mediated (CMI) responses to coronavirus disease 2019 (COVID-19) vaccines in this population. Therefore, the purpose study was examine HI and CMI up 6 months post-COVID-19 dose 3 adults IEIs. Methods A multi-center prospective observational conducted across Canada collect severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)-specific...
Focal atrial tachycardia (AT) arising from the crista terminalis, pulmonary veins, para-Hisian region, tricuspid annulus and coronary sinus ostium regions are well described. Less information exists regarding AT right appendage (RAA).The study was done to characterise electrocardiographic electrophysiologic features radiofrequency ablation (RFA) of focal RAA.Six patients a consecutive series 250 undergoing RFA for reported. Mapping performed during or frequent ectopy identify earliest...
Immune response to COVID-19 vaccine is diminished in patients with hematologic malignancy. There limited data regarding doses these patients. To quantify the humoral immune engendered by 4th and subsequent of SARS-CoV-2 vaccination as measured anti-Spike (anti-S) antibody levels, based on dried blood spot (DBS) testing, malignancies. Anti-S binds spike protein virus indicative immunogenicity. We conducted a prospective study malignancies between August 2021 January 2023 at 12 sites across...
Targeted neuroimaging plays a vital role in evaluating pathologies and guiding interventions deep brain regions, such as biopsy, laser ablation, stimulation. However, current techniques face several challenges when it comes to imaging the brain. These include limited depth, narrow field of view, low resolution, lack real‐time stereotactic deployment capabilities. To address these challenges, patient‐mounted neuro optical coherence tomography (neuroOCT) system that combines lightweight 5...
The forkhead box F2 (Foxf2) gene suppresses epithelial-mesenchymal transition via the modulation of transcription zinc finger E-box-binding homeobox 1 (Zeb1) and epithelial (E)-cadherin, thereby inhibiting tumor metastasis.Additionally, specific binding microRNA (miR)-200c to Foxf2 mRNA impedes metastatic pulmonary cancer.However, role miR-200c in breast cancer is still unknown.Therefore, this study, mimics were transfected into highly cell line MDA-MB-231.Their invasion migration abilities...
Background Gestational weight gain (GWG) is a major risk factor of poor pregnancy outcomes. Obese pregnant women frequently report bias and discrimination when dealing with healthcare providers (HCPs). Effective communication GWG recommendations may impact risks. Study objectives were to identify perceptions HCPs in communicating potential gaps/opportunities that could be addressed the development appropriate materials/programmes. Methods: A survey tool was created using Theory Planned...
Prediction of acute kidney transplant rejection remains imperfect despite several known risk factors. There is an increasing appreciation the potential importance vitamin D pathway in immunological disease and transplantation.The purpose this study was to determine association 25-hydroxyvitamin 1,25-dihydroxyvitamin with rejection.This a prospective cohort study.Three academic adult programs Ontario, Canada, were chosen.All consecutive patients at 3 institutions who received solitary...
Abstract Background Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) is a clinical syndrome with various causes. It not uncommon that COPD patients presenting dyspnea have multiple causes for their symptoms including AECOPD, pneumonia, or congestive heart failure occurring concurrently. Methods To identify clinical, radiographic, and laboratory characteristics might help distinguish AECOPD from another dominant in history COPD, we conducted retrospective cohort study...
Background: We conducted a prospective observational study of patients undergoing elective primary hip or knee replacements to examine the feasibility postoperative home monitoring system as transitional care support following their surgery in real time.