A5009958327- Immunodeficiency and Autoimmune Disorders
- Blood disorders and treatments
- Cytomegalovirus and herpesvirus research
- Viral gastroenteritis research and epidemiology
- Pharmaceutical and Antibiotic Environmental Impacts
- Hypothalamic control of reproductive hormones
- Blood groups and transfusion
- Respiratory Support and Mechanisms
- Anesthesia and Sedative Agents
- Immune Cell Function and Interaction
- Anesthesia and Pain Management
- Virus-based gene therapy research
- CAR-T cell therapy research
- COVID-19 Impact on Reproduction
- Immune responses and vaccinations
- Parvovirus B19 Infection Studies
- Viral Infections and Immunology Research
- Airway Management and Intubation Techniques
- Reproductive System and Pregnancy
- Antibiotic Resistance in Bacteria
- Glioma Diagnosis and Treatment
- Antibiotic Use and Resistance
- Scoliosis diagnosis and treatment
- Cystic Fibrosis Research Advances
- NF-κB Signaling Pathways
University of Alberta
2014-2025
Stollery Children's Hospital
2014-2024
Cochin University of Science and Technology
2023-2024
Jawaharlal Nehru Medical College
2024
University of Florida
2023-2024
University of Lincoln
2022
Alberta Hospital Edmonton
2022
Amrita Institute of Medical Sciences and Research Centre
2020-2021
Aarupadai Veedu Medical College & Hospital
2019
Hospital for Sick Children
2019
Abstract Growing evidence suggests receipt of live‐attenuated viral vaccines after solid organ transplant (SOT) has occurred and is safe needed due to lapses in herd immunity. A 2‐day consortium experts infectious diseases, transplantation, vaccinology, immunology was held with the objective review create expert recommendations for clinicians when considering live post‐SOT. For consideration VV MMR post‐transplant, exists only kidney liver recipients. vaccine post‐SOT, consider vaccination...
Abstract Human needs have led to the development of various products which are produced in industries. These industries turn become a source environmental concerns. As release regulated and unregulated contaminants into water bodies, it has serious concern for all living organisms. Various emerging contaminates from like pesticides, pharmaceuticals drugs hormones, antibiotics, dyes, etc., along with byproducts new complexes contaminate bodies. Numerous traditional approaches been utilized...
Newborn screening (NBS) programs for severe combined immunodeficiency facilitate early diagnosis of and promote treatment with hematopoietic stem cell transplantation, resulting in improved clinical outcomes. Infants congenital athymia are also identified through NBS because T-cell lymphopenia. With the expanding introduction programs, referrals athymic patients thymus transplantation have recently increased at Great Ormond Street Hospital (GOSH) (London, United Kingdom).
Purpose Many individuals with inborn errors of immunity (IEIs) have poor humoral immune (HI) vaccine responses. Only a few studies examined specific cell-mediated (CMI) responses to coronavirus disease 2019 (COVID-19) vaccines in this population. Therefore, the purpose study was examine HI and CMI up 6 months post-COVID-19 dose 3 adults IEIs. Methods A multi-center prospective observational conducted across Canada collect severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)-specific...
Mastocytosis is characterized by the clonal expansion of mast cells, with deposition into various organs and variable clinical presentation depending on subtype. It generally results from a mutation in KIT gene, which encodes for production receptor tyrosine kinases, constitutive activity abnormal cell growth proliferation. In pediatric patients, cutaneous mastocytosis (CM) form predominates, systemic (SM) rarely reported. Accordingly, course management are not well described. We describe...
Severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) is a highly infectious disease and healthcare workers are at constant risk for contracting it. Nowadays, aerosol box used in conjunction with WHO-recommended safety kits, to avoid health from getting SARS-CoV-2 infection during aerosol-generating procedures. In our study, we compared the ease of oral intubation C-MAC video laryngoscope direct laryngoscopy, when was used. The secondary objectives were compare incidence airway loss,...
Abstract Optimal strategies to prevent cytomegalovirus ( CMV ) disease following pediatric solid organ transplantation remain controversial. The purpose of this study was review the outcomes a risk‐stratified strategy that uses hybrid or prophylactic for donor (D)+ recipient (R)− patients, preemptive D+R+/D−R+, and clinical follow‐up alone D−R+ patients. A retrospective chart undertaken at Stollery Children's Hospital in Edmonton, Alberta transplants 2004 through 2010. Transplants were...
Porencephaly is an uncommon neurological condition characterized by cystic cavities or holes in the cerebral hemispheres of brain filled with cerebrospinal fluid. There are two types porencephaly: acquired porencephaly, also known as pseudo-porencephaly, and congenital true porencephaly. Acquired encephaloclastic typically results from late prenatal perinatal vascular lesions caused arterial ischemic stroke venous thrombosis. Congenital genetic arises maldevelopment during early neuronal...
Late-onset disease with Group B Streptococcus (GBS LOD) remains a significant problem in neonates. Unlike early-onset disease, rates of GBS LOD have not changed prenatal testing. Effects can be severe and thus identifying risk factors for LOD, such as hypervirulence genes, may help managing these infants.We present case neonate capsular serotype III sepsis without meningitis that recurred 6 days after 10-day-treatment period IV ampicillin. The second episode was characterized by sepsis,...
Pheochromocytomas are rare catecholamine-secreting tumors that arise from chromaffin tissue within the adrenal medulla and extra-adrenal sites. Due to excess secretion of hormones, these often cause debilitating symptoms a poor quality-of-life. Although medical management plays significant role in treatment pheochromocytoma patients, surgical excision remains only cure. Pheochromocytoma usually has three classic symptoms-headache, sweating heart palpitations (a fast beat) association with...
<p class="abstract"><strong>Background:</strong> Chronic maxillary sinusitis is one of the common ENT problems. Accessory ostium (AMO) has been postulated in many publications to play a role development chronic sinusitis. AMO found medial wall sinus and located lateral nose. It’s frequently identified routine nasal endoscopy. The variations location have evaluated by endoscopy live subjects or through cadaver dissections authors. This study conducted identify prevalence...
Inborn errors of immunity (IEI) are a heterogeneous group genetic diseases that impact normal immune development and function. Individual IEI rare, but collectively, can represent an important health burden. Little is known about the types seen in Canadian First Nations (FN) Inuit populations. We sought to understand spectrum serious FN Nunavut children, as starting point for improving awareness these conditions community care workers. A questionnaire was distributed participating pediatric...