A5085914827- Vaccine Coverage and Hesitancy
- Bacterial Infections and Vaccines
- Influenza Virus Research Studies
- SARS-CoV-2 and COVID-19 Research
- Pneumonia and Respiratory Infections
- Respiratory viral infections research
- COVID-19 Impact on Reproduction
- COVID-19 Clinical Research Studies
- Kawasaki Disease and Coronary Complications
- Food Allergy and Anaphylaxis Research
- Pregnancy and Medication Impact
- Reproductive System and Pregnancy
- Infectious Encephalopathies and Encephalitis
- Virology and Viral Diseases
- Streptococcal Infections and Treatments
- Immunodeficiency and Autoimmune Disorders
- Heparin-Induced Thrombocytopenia and Thrombosis
- Drug-Induced Adverse Reactions
- Epilepsy research and treatment
- Viral Infections and Immunology Research
- Viral gastroenteritis research and epidemiology
- Mechanical Circulatory Support Devices
- Vasculitis and related conditions
- COVID-19 and Mental Health
- Neonatal Respiratory Health Research
Dalhousie University
2016-2025
University of Alberta
2021-2025
Women and Children’s Health Research Institute
2024
Izaak Walton Killam Health Centre
2015-2024
Research Network (United States)
2024
Impact
2023
Nova Scotia Health Authority
2016-2023
University of British Columbia
2021-2022
University of Toronto
2015-2021
Canadian Paediatric Society
2021
Abstract Growing evidence suggests receipt of live‐attenuated viral vaccines after solid organ transplant (SOT) has occurred and is safe needed due to lapses in herd immunity. A 2‐day consortium experts infectious diseases, transplantation, vaccinology, immunology was held with the objective review create expert recommendations for clinicians when considering live post‐SOT. For consideration VV MMR post‐transplant, exists only kidney liver recipients. vaccine post‐SOT, consider vaccination...
<h3>Background:</h3> Risk factors for severe outcomes of SARS-CoV-2 infection are not well established in children. We sought to describe pediatric hospital admissions associated with Canada and identify risk more disease. <h3>Methods:</h3> conducted a national prospective study using the infrastructure Canadian Paediatric Surveillance Program (CPSP). Cases involving children who were admitted microbiologically confirmed reported from Apr. 8 Dec. 31 2020, through weekly online questionnaires...
Importance Respiratory syncytial virus (RSV) is a leading cause of pediatric hospitalizations. Objective To describe the epidemiology and burden RSV-associated hospitalizations among children adolescents in Canadian tertiary hospitals from 2017 to 2022, including changes during COVID-19 pandemic. Design, Setting, Participants This cross-sectional study was conducted 5 RSV seasons (2017-2018 2021-2022) at 13 care centers Immunization Monitoring Program Active (IMPACT) program. Hospitalized...
Background. Neisseria meningitidis causes 500 000 cases of septicemia and meningitis worldwide annually, with approximately 200 in Canada each year. Previous studies describe a case-fatality rate 5%–15% up to 20% survivors suffering from long-term disability.
The COVID-19 pandemic resulted in unprecedented implementation of wide-ranging public health measures globally. During the pandemic, dramatic decreases seasonal influenza virus detection have been reported worldwide. Information on impact paediatric influenza-related hospitalisations is limited. We describe hospitalisation children Canada following onset pandemic. Data hospitalisations, intensive care unit (ICU) admissions and in-hospital deaths across were obtained from Canadian...
The Brighton Collaboration (BC) has formulated a number of case definitions which have primarily been applied to adverse events special interest in the context vaccine safety surveillance. This is revision 2007 BC definition for anaphylaxis. Recently, widely used evaluating reports suspected anaphylaxis following COVID-19 vaccination. led debate about performance comparison with those from US National Institute Allergy and Infectious Disease/Food Anaphylaxis Network (NIAID/FAAN) World...
Maternal vaccination is an important area of research and requires appropriate internationally comparable definitions safety standards. The GAIA group, part the Brighton Collaboration was created with mandate proposing standardised applicable to maternal vaccine research. This study proposes international for neonatal infections. infections working group performed a literature review using Medline, EMBASE Cochrane collaboration collected in use public health networks. common criteria derived...
Children living with chronic comorbid conditions are at increased risk for severe COVID-19, though there is limited evidence regarding the risks associated specific and which children may benefit from targeted COVID-19 therapies. The objective of this study was to identify factors disease among hospitalized in Canada.We conducted a national prospective on microbiologically confirmed SARS-CoV-2 infection via Canadian Paediatric Surveillance Program (CPSP) April 2020-May 2021. Cases were...
COVID-19 vaccines require enhanced safety monitoring after emergency approval. The Canadian National Vaccine Safety Network monitors the of and provides for healthy, auto-immune, immunocompromised, pregnant breastfeeding populations allows detection signals.Online participant reporting health events in vaccinated unvaccinated individuals 12 years age older is captured three surveys: 1 week dose 1, 2 7 months 1. Medically attended are followed up by telephone. number, percentage, rate per 10...
Recent increases in pertussis morbidity and mortality rates among young infants have led to a recommendation some countries for vaccination against during pregnancy. Having data on the burden of pediatric large population over time is important establishing true disease acellular (aP) vaccine era. Here, we describe age-specific epidemiology children hospitalized with 17 years across Canada aP
Abstract Objective To determine whether any association exists between exposure to 2009 pandemic H1N1 (pH1N1) influenza vaccination during pregnancy and negative health outcomes in early childhood. Design Retrospective cohort study. Setting Population based birth registry linked with administrative databases the province of Ontario, Canada. Participants All live births from November through October 2010 (n=104 249) were included, children followed until 5 years age ascertain study outcomes....
Background. Before 2001, the incidence of invasive meningococcal disease (IMD) in Canada was 1.0 per 100 000 year, with 40% cases caused by serogroup C organisms. During 2001–2005 all provinces introduced conjugate vaccine (MCCV) into their routine infant immunization schedule. Methods. Active, prospective, population-based surveillance IMD children and adults conducted Canadian Immunization Monitoring Program, ACTive (IMPACT) during 2002–2012. Inclusion criteria were admission to hospital...
Within 2 years after the start of coronavirus disease 2019 (COVID-19) pandemic, novel severe acute respiratory syndrome vaccines were developed, rigorously evaluated in large phase 3 trials, and administered to more than 5 billion individuals globally. However, adverse events special interest (AESIs) have been described post-implementation, including myocarditis receipt messenger RNA (mRNA) thrombosis with thrombocytopenia adenoviral vector vaccines. AESIs are rare (<1 10/100 000 vaccinees)...
To identify risk factors for severe disease in children hospitalised SARS-CoV-2 infection.Multicentre retrospective cohort study.18 hospitals Canada, Iran and Costa Rica from 1 February 2020 to 31 May 2021.Children<18 years of age symptomatic PCR-positive infection, including multisystem inflammatory syndrome (MIS-C).Severity on the WHO COVID-19 Clinical Progression Scale was used ordinal logistic regression analyses.We identified 403 hospitalisations. Median 3.78 (IQR 0.53-10.77). At least...
Seasonal influenza vaccination in pregnancy can reduce illness among pregnant women and newborns. Evidence is limited on whether seasonal associated with adverse childhood health outcomes.To assess the association between maternal during early outcomes.Retrospective cohort study, using a birth registry linked administrative data. All live births Nova Scotia, Canada, October 1, 2010, March 31, 2014, were included, follow-up until 2016. Adjusted hazard ratios (HRs) incidence rate (IRRs) 95%...