A5066158785- Vaccine Coverage and Hesitancy
- Influenza Virus Research Studies
- Bacterial Infections and Vaccines
- Cytomegalovirus and herpesvirus research
- Pneumonia and Respiratory Infections
- COVID-19 Impact on Reproduction
- Respiratory viral infections research
- Neonatal and Maternal Infections
- Herpesvirus Infections and Treatments
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Network Security and Intrusion Detection
- Internet Traffic Analysis and Secure E-voting
- Immune responses and vaccinations
- Immunodeficiency and Autoimmune Disorders
- Parvovirus B19 Infection Studies
- Kawasaki Disease and Coronary Complications
- Neonatal Respiratory Health Research
- Hearing Loss and Rehabilitation
- Network Packet Processing and Optimization
- Viral gastroenteritis research and epidemiology
- Streptococcal Infections and Treatments
- Global Maternal and Child Health
- Tuberculosis Research and Epidemiology
- Noise Effects and Management
NIHR Southampton Biomedical Research Centre
2020-2025
University Hospital Southampton NHS Foundation Trust
2012-2025
University of Southampton
2017-2025
Children's National
2024
St George's, University of London
2013-2023
University of Oxford
2020-2023
Churchill Hospital
2023
NIHR Clinical Research Network
2021-2023
University of Manchester
2023
Medical Research Council
2023
In communities with high rates of coronavirus disease 2019, reports have emerged children an unusual syndrome fever and inflammation.
The design of the IP protocol makes it difficult to reliably identify originator an packet. Even in absence any deliberate attempt disguise a packet's origin, wide-spread packet forwarding techniques such as NAT and encapsulation may obscure true source. Techniques have been developed determine source large flows, but, date, no system has presented track individual packets efficient, scalable fashion.We present hash-based technique for traceback that generates audit trails traffic within...
The design of the IP protocol makes it difficult to reliably identify originator an packet. Even in absence any deliberate attempt disguise a packet's origin, widespread packet forwarding techniques such as NAT and encapsulation may obscure true source. Techniques have been developed determine source large flows, but, date, no system has presented track individual packets efficient, scalable fashion. We present hash-based technique for traceback that generates audit trails traffic within...
Respiratory syncytial virus (RSV) is the dominant cause of severe lower respiratory tract infection in infants, with most cases concentrated among younger infants.
Altered immune responses might contribute to the high morbidity and mortality observed in human immunodeficiency virus (HIV)-exposed uninfected infants.To study association of maternal HIV infection with maternal- infant-specific antibody levels Haemophilus influenzae type b (Hib), pneumococcus, Bordetella pertussis antigens, tetanus toxoid, hepatitis B surface antigen.A community-based cohort Khayelitsha, Western Cape Province, South Africa, between March 3, 2009, April 28, 2010, 109...
Coronavirus-like particles (CoVLP) that are produced in plants and display the prefusion spike glycoprotein of original strain severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) combined with an adjuvant (Adjuvant System 03 [AS03]) to form candidate vaccine.In this phase 3, multinational, randomized, placebo-controlled trial conducted at 85 centers, we assigned adults (≥18 years age) a 1:1 ratio receive two intramuscular injections CoVLP+AS03 vaccine or placebo 21 days apart. The...
The design of the IP protocol makes it difficult to reliably identify originator an packet. Even in absence any deliberate attempt disguise a packet's origin, wide-spread packet forwarding techniques such as NAT and encapsulation may obscure true source. Techniques have been developed determine source large flows, but, date, no system has presented track individual packets efficient, scalable fashion.We present hash-based technique for traceback that generates audit trails traffic within...
Introduction. In England, antenatal pertussis immunization using a tetanus/low-dose diphtheria/5-component acellular-pertussis/inactivated-polio (TdaP5/IPV) vaccine was introduced in October 2012. We assessed infant responses to antigens the maternal and those conjugated tetanus (TT) or diphtheria toxin variant, CRM.
Trans-placental antibody transfer from mother to fetus provides protection infection in the first weeks of life, and four different subclasses IgG (IgG1, IgG2, IgG3, IgG4) have diverse roles against infection. In this study, we evaluated concentrations trans-placental ratios a healthy UK-based cohort mother-cord pairs, investigated associations with maternal, obstetric, fetal factors. agreement previous studies, found strong association between maternal cord for all subclasses. We report...
Paediatric Multisystem Inflammatory Syndrome temporally associated with SARS-CoV-2 (PIMS-TS), first identified in April 2020, shares features of both Kawasaki disease (KD) and toxic shock syndrome (TSS). The surveillance describes the epidemiology clinical characteristics PIMS-TS United Kingdom Ireland. Public Health England initiated prospective national through British Surveillance Unit. Paediatricians were contacted monthly to report PIMS-TS, KD TSS cases electronically complete a...
Immunization in pregnancy provides a promising contribution to globally reducing neonatal and under-five childhood mortality morbidity. Thorough assessment of benefits risks for the primarily healthy pregnant women their unborn babies is required. The GAIA project was formed response call World Health Organization concerted approach actively monitor safety vaccines immunization programs. aims improve quality outcome data from clinical vaccine trials with specific focus on needs requirements...
The International Society of Ultrasound in Obstetrics and Gynecology (ISUOG) is a scientific organization that encourages sound clinical practice, high-quality teaching research related to diagnostic imaging women's healthcare. ISUOG Clinical Standards Committee (CSC) has remit develop Practice Guidelines Consensus Statements as educational recommendations provide healthcare practitioners with consensus-based approach, from experts, for imaging. They are intended reflect what considered by...
BackgroundPaediatric multisystem inflammatory syndrome temporally associated with SARS-CoV-2 (PIMS-TS), also known as in children (MIS-C) emerged April, 2020. The paediatric comparisons within the RECOVERY trial aimed to assess effect of intravenous immunoglobulin or corticosteroids compared usual care on duration hospital stay for PIMS-TS and compare tocilizumab (anti-IL-6 receptor monoclonal antibody) anakinra (anti-IL-1 antagonist) those inflammation refractory initial treatment.MethodsWe...