A5086137427- COVID-19 epidemiological studies
- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- Kawasaki Disease and Coronary Complications
- Mechanical Circulatory Support Devices
- COVID-19 and Mental Health
- Urban, Neighborhood, and Segregation Studies
- SARS-CoV-2 detection and testing
- Congenital Heart Disease Studies
- Bacillus and Francisella bacterial research
- Sepsis Diagnosis and Treatment
- Long-Term Effects of COVID-19
- Yersinia bacterium, plague, ectoparasites research
- Geographic Information Systems Studies
- COVID-19 Pandemic Impacts
- Data Management and Algorithms
- Microbial infections and disease research
- Cardiac Structural Anomalies and Repair
- Web Data Mining and Analysis
- Viral Infections and Outbreaks Research
- Vibrio bacteria research studies
- Respiratory viral infections research
- Vaccine Coverage and Hesitancy
UK Health Security Agency
2022-2024
University of Glasgow
2024
Public Health England
2020-2022
Guidance (United Kingdom)
2022
Government of the United Kingdom
2021-2022
Paediatric Multisystem Inflammatory Syndrome temporally associated with SARS-CoV-2 (PIMS-TS), first identified in April 2020, shares features of both Kawasaki disease (KD) and toxic shock syndrome (TSS). The surveillance describes the epidemiology clinical characteristics PIMS-TS United Kingdom Ireland. Public Health England initiated prospective national through British Surveillance Unit. Paediatricians were contacted monthly to report PIMS-TS, KD TSS cases electronically complete a...
We investigate the effect of school closure and subsequent reopening on transmission COVID-19, by considering Denmark, Norway, Sweden German states as case studies. By comparing growth rates in daily hospitalizations or confirmed cases under different interventions, we provide evidence that closures contribute to a reduction rate approximately 7 days after implementation. Limited attendance, such older students sitting exams partial return younger year groups, does not appear significantly...
Objectives: Following detection of the first virologically-confirmed cases COVID-19 in Great Britain, an enhanced surveillance study was initiated by Public Health England to describe clinical presentation, course disease and identify risk factors for infection few hundred cases. Methods: Information collected on according First Few X WHO protocol. Case-control analyses sensitivity, specificity predictive value symptoms were conducted. Point prevalences underlying health conditions among UK...
Abstract We investigate the effect of school closure and subsequent reopening on transmission COVID-19, by considering Denmark, Norway, Sweden, German states as case studies. By comparing growth rates in daily hospitalisations or confirmed cases under different interventions, we provide evidence that closures contribute to a reduction rate approximately 7 days after implementation. Limited attendance, such older students sitting exams partial return younger year groups, does not appear...
To describe the clinical presentation, course of disease and health-care seeking behaviour first few hundred cases coronavirus 2019 (COVID-19) in United Kingdom Great Britain Northern Ireland.
Air travel plays an important role in the cross-border spread of infectious diseases. During SARS-CoV-2 pandemic many countries introduced strict border testing protocols to monitor incursion virus. However, high implementation costs and significant inconvenience passengers have led public health authorities consider alternative methods disease surveillance at borders. Aircraft wastewater monitoring has been proposed as one such alternative. In this paper we assess theoretical limits...
Paediatric Multisystem Inflammatory Syndrome (PIMS-TS) is a rare life-threatening complication that typically occurs several weeks after SARS-CoV-2 infection in children and young people (CYP). We used national regional-level data from the COVID-19 pandemic waves England to develop model predict PIMS-TS cases.
Abstract Background Air travel plays an import role in the cross-border spread of infectious diseases. During SARS-CoV-2 pandemic many countries introduced strict border testing protocols to monitor incursion virus. However, high implementation cost and significant inconvenience passengers has led public health authorities consider alternative methods disease surveillance at borders. Aircraft wastewater monitoring been proposed as one such alternative. In this paper we assess theoretical...
Abstract. Geoparsing, the process of linking locations within text to sets geographic coordinates, plays an important role in extraction and analysis information from unstructured textual data. With rapid growth availability user-generated data online sources, there is increasing demand for reliable geoparsing methods. Central many these methods accurate identification toponyms text. For some applications, however, simple insufficient. Problems which require association a piece containing...
Reverse epidemiology is a mathematical modelling tool used to ascertain information about the source of pathogen, given spatial and temporal distribution cases, hospitalisations deaths. In context deliberately released such as Bacillus anthracis (the disease-causing organism anthrax), this can allow responders quickly identify location timing release, well other factors strength realized wind speed direction at release. These estimates then be parameterise predictive mechanistic model,...
Abstract Understanding the scale of threat posed by SARS-CoV2 B.1.1.529, or Omicron , variant formed a key problem in public health early part 2022. Early evidence indicated that was more transmissible and less severe than previous variants. As virus expected to spread quickly through population England, it important some understanding immunological landscape country developed. This paper attempts estimate number people with good immunity variant, defined as either recent infection two doses...
Background: Paediatric multisystem inflammatory syndrome temporally associated with SARS-CoV-2 (PIMS-TS), first identified in April 2020, shares features of both Kawasaki disease (KD) and toxic shock (TSS). Methods: Public Health England initiated prospective national surveillance PIMS-TS through the British Surveillance Unit. Paediatricians were contacted monthly to report PIMS-TS, KD TSS cases electronically complete a detailed clinical questionnaire. Cases symptom onset between 01 March...
Background: Paediatric Multisystem Inflammatory Syndrome (PIMS-TS) is a rare life-threatening complication that typically occurs several weeks after SARS-CoV-2 infection in children and young people (CYP). We used national regional-level data from the COVID-19 pandemic wave England to develop optimise model predict PIMS-TS cases subsequent waves.Methods: infections CYP aged 0-15 years were estimated using PHE-Cambridge real-time model. identified through British Surveillance Unit during...
Understanding the scale of threat posed by SARS-CoV2 B.1.1.529, or Omicron, variant formed a key problem in public health early part 2022. Early evidence indicated that was more transmissible and less severe than previous variants. As virus expected to spread quickly through population England, it important some understanding immunological landscape country developed. This paper attempts estimate number people with good immunity Omicron variant, defined as either recent infection two doses...
Background: Paediatric Multisystem Inflammatory Syndrome (PIMS-TS) is a rare life-threatening complication that occurs in some children two to four weeks after SARS-CoV-2 infection. Although the precise causal mechanisms underpinning relationship between and PIMS-TS are unclear, several recent studies have confirmed strong temporal association. This study provides further evidence support of link. A novel methodology presented whereby incidence parameters estimated from data published on...
Abstract The roll-out of COVID-19 vaccines in the England has generally been very good – with over 80% 12s having received two doses vaccine by start February 2022, and 67% a further booster dose. Despite this, there is small section population who remain unvaccinated, either due to lack access, hesitancy or resistant vaccination. In this report we estimate that, during 2021, were approximately 3,500 deaths unvaccinated people, could otherwise have reasonably expected receive Further, show...
This paper presents a method used to rapidly assess the incursion and establishment of community transmission suspected SARS-CoV-2 variant concern Delta (lineage B.1.617.2) into UK in April May 2021. The described is independent any genetically sequenced data, so avoids inherent lag times involved sequencing cases. We show that, between 1 12 2021, there was strong correlation local authorities with high numbers imported positive cases from India COVID-19 case rates, that this relationship...
Abstract Reverse epidemiology is a mathematical modelling tool used to ascertain information about the source of pathogen, given spatial and temporal distribution cases, hospitalisations deaths. In context deliberately released such as Bacillus anthracis (the disease-causing organism anthrax), this can allow responders quickly identify location timing release, well other factors strength realized wind speed direction at release. These estimates then be parameterise predictive mechanistic...