A5087212223- Robotic Mechanisms and Dynamics
- Soft Robotics and Applications
- Robot Manipulation and Learning
- Piezoelectric Actuators and Control
- Modular Robots and Swarm Intelligence
- Advanced Surface Polishing Techniques
- Advanced Materials and Mechanics
- Mesenchymal stem cell research
- Dynamics and Control of Mechanical Systems
- Iterative Learning Control Systems
- Structural Analysis and Optimization
- Mechanical Engineering and Vibrations Research
- Mechatronics Education and Applications
- Bone Tissue Engineering Materials
- Micro and Nano Robotics
- Advanced MEMS and NEMS Technologies
- Robotic Locomotion and Control
- Advanced machining processes and optimization
- Robotic Path Planning Algorithms
- Sensor Technology and Measurement Systems
- Advanced Sensor and Energy Harvesting Materials
- Cellular Mechanics and Interactions
- Wound Healing and Treatments
- Industrial Technology and Control Systems
- Advanced Control Systems Design
Union Hospital
2024-2025
Huazhong University of Science and Technology
2023-2025
Hubei Zhongshan Hospital
2023-2025
Wuhan University
2023-2025
Yanshan University
2016-2025
Union Hospital
2023
Ministry of Education of the People's Republic of China
2019
CAE (Canada)
2006
Bone nonunion poses an urgent clinical challenge that needs to be addressed. Recent studies have revealed the metabolic microenvironment plays a vital role in fracture healing. Macrophages and bone marrow-derived mesenchymal stromal cells (BMSCs) are important targets for therapeutic interventions fractures. Itaconate is TCA cycle metabolite has emerged as potent macrophage immunomodulator limits inflammatory response. During osteogenic differentiation, BMSCs tend undergo aerobic glycolysis...
Abstract Infected fracture healing is a complicated process that includes intricate interactions at the cellular and molecular levels. In addition to angiogenesis osteogenesis, significance of neurogenesis in has also been recognized recent years. Here, nanocomposite hydrogel containing pH‐responsive zinc‐gallium‐humic acids (HAs) nanoparticles developed. Through timed release Zn 2+ , Ga 3+ HAs, exhibits potent antibacterial effects promotes angiogenesis, neurogenesis. The enhanced further...
Despite good performance in grasping irregular fragile objects, soft grippers exhibiting low stiffness, and carrying capacity lack multidirectional ability the case of inclination. To address this problem, we propose a novel rigid coupling variable stiffness module that employs folded plate mechanism (FPM) to provide loading combines it with particle jamming achieve local characteristics finger structure. Hence, robot is developed realize loading. The bending control gripper realized by...
Inspired by the physiological structure of hand capable realizing continuous change in finger stiffness when grasping objects different masses, a self-locking soft continuum robot with large variable-stiffness range based on particle jamming and fibre is proposed this paper to meet requirements it practical application. In paper, variable derived due good fluidity rigidity spherical particles low elasticity high toughness fibres. Then, an analysis model established deduce its condition,...
Nowadays improving the accuracy and enlarging measuring range of six-axis force sensors for wider applications in aircraft landing, rocket thrust, spacecraft docking testing experiments has become an urgent objective. However, it is still difficult to achieve high large with traditional parallel due influence gap friction joints. Therefore, overcome mentioned limitations, this paper proposed a 6-Universal-Prismatic-Universal-Revolute (UPUR) joints mechanism flexible develop measurement...
Abstract Kinematic synthesis design typically relies on predefined motion types, but traditional mechanism theories are primarily applied at the theoretical level, limiting their practical application in engineering. To address this, a novel rigid-body identification method is developed, aimed identifying quotient manifold G/H. Firstly, based of MG/H, Lie subgroup generator theorem introduced. Secondly, finite screw displacement theory, Chasles decomposition models for MG/H developed....
Abstract Impaired fracture healing in diabetic patients poses a persistent clinical challenge, with underlying mechanisms that remain to be fully elucidated. These findings reveal high glucose microenvironments generate excessive reactive oxygen species bone marrow mesenchymal stem cells (BMSCs) and marrow‐derived macrophages (BMDMs), leading mitochondrial dysfunction metabolic impairment. pathophysiological disruptions suppress osteogenic differentiation BMSCs while driving pro‐inflammatory...
Abstract Metal–organic frameworks (MOFs) exhibit exceptional characteristics, including high porosity and adjustable properties, rendering them highly suitable for biomedical applications. Recently, researchers have directed their attention toward the integration of MOFs into composites bone tissue regeneration (BTE), presenting distinct advantages over conventional substitutes. In this comprehensive review, authors delve latest advancements concerning MOF‐integrated BTE. This exploration...
SUMMARY This paper investigates a 6-degree-of-freedom foldable parallel mechanism for the ship-based stabilized platform, which is driven by closed chain linkages. The velocity and acceleration mappings between moving platform inputs of linkages are deduced in form first- second-order influence coefficient matrices. continuous stiffness matrix deduced; furthermore, translation rotational along any direction also deduced. With directional stiffness, singularity analyzed, explanation given...
As a position servo system to isolate disturbance from its carrier, stabilized platform requires high-precision and high-adaptability control. However, conventional integer-order PID (IOPID) control fails meet that requirement. In this paper, new controller design scheme is proposed for based on fractional calculus. The designed called fractional-order (FOPID) controller, which has two extra parameters compared controller. On one hand, it provides more degrees of freedom FOPID the other...
Inspired by the twisting and hanging phenomenon of vines, this paper proposes designs a passive variable stiffness soft robotic gripper to grasp an object in simple robust manner using principle jamming. This method has characteristics high reliability good stability, which can achieve grasping rigid load-bearing object. Firstly, according two key issues, design model is proposed, proposed analyzed, relationship between revealed. Secondly, created conventional motor drive method, process...
SUMMARY The force analysis of parallel manipulators is one the important issues for mechanical design and control, but it quite difficult often because excessive unknowns. A new approach using screw theory a 3-RPS mechanism proposed in this paper. It able to markedly reduce number unknowns even make simultaneous equations solve not more than six each time, which may be called decoupling. With method, first main-pair reactions need solved for, then, active forces constraint all other...
In the development of multi-dimensional force sensor, dimension coupling is ubiquitous factor restricting improvement measurement accuracy. To effectively reduce influence on parallel a novel three-dimensional sensor proposed using mechanical decoupling principle, and friction reduced by making rolling instead sliding friction. this paper, mathematical model established combining with structure modeling analysis are carried out. The degree (ε) designed defined calculated, calculation results...
In view of the demand for flexible drive and large load soft robot in practical application, a novel type flexible-actuated multi-degree-of-freedom (multi-DOF) parallel is designed. The proposed combination three groups elements (FAEs) realizes by increasing bearing area at connection between units (FAUs). order to improve driving flexibility, multi-layer FAU used independently so as realize omnidirectional bending movement pneumatic drive. With coupled analysis terms motion force, mapping...
An over-constrained, parallel six-dimensional force sensor has various advantages, including its ability to bear heavy loads and provide redundant measurement information. These advantages render the valuable in important applications field of aerospace (space docking tests, etc). The stiffness each component over-constrained structure a considerable influence on internal distribution structure. Thus, model changes when branches are under tensile or compressive force. This study establishes...
To improve the performances of parallel 6-axis force sensor with Stewart platform, paper plots indices atlases based on screw theory and physical model solution space, summaries laws how structure parameters affect indices. Then, sizable sensor's are optimized in nonlinear single objective multi-objective respectively, order to obtain better than that initial ones. So, powerful basis method raised for design optimization platform general spherical joint.