Y LI

ORCID: 0000-0003-4718-1825
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About
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Research Areas
  • Tissue Engineering and Regenerative Medicine
  • Hepatitis B Virus Studies
  • Electrospun Nanofibers in Biomedical Applications
  • Analytical Chemistry and Chromatography
  • Analytical Methods in Pharmaceuticals
  • Antibiotics Pharmacokinetics and Efficacy
  • Medicinal Plants and Neuroprotection
  • Memory and Neural Mechanisms
  • Protein purification and stability
  • Calpain Protease Function and Regulation
  • Sirtuins and Resveratrol in Medicine
  • Medicinal Plant Pharmacodynamics Research
  • Plant Genetic and Mutation Studies
  • Antioxidant Activity and Oxidative Stress
  • Biological and pharmacological studies of plants
  • Magnetic and Electromagnetic Effects
  • Layered Double Hydroxides Synthesis and Applications
  • Aldose Reductase and Taurine
  • Liver physiology and pathology
  • PARP inhibition in cancer therapy
  • Traditional Chinese Medicine Analysis
  • Mesoporous Materials and Catalysis
  • Light effects on plants
  • Pharmacology and Obesity Treatment
  • Digestive system and related health

Institute of Process Engineering
2007-2024

University of Chinese Academy of Sciences
2024

Zhujiang Hospital
2024

Southern Medical University
2024

Hunan Institute of Engineering
2008

Lawson Health Research Institute
2008

Western University
2008

Chinese PLA General Hospital
2007

Shenyang Pharmaceutical University
2005-2006

Zhejiang University
2006

Late treatment with erythropoietin (EPO), as well the administration before onset of or during acute stage myocardial infarction (MI), has recently been shown to mitigate post-MI heart failure. We investigated mechanisms, including downstream signaling pathways, for beneficial effect late EPO on chronic failure.EPO (1500 U/kg, twice a week) was administered mice beginning 6 weeks after induction large MI. The 4 diminished left ventricular dilatation and improved function. It significantly...

10.1016/j.cardiores.2006.06.003 article EN Cardiovascular Research 2006-06-07

10.1016/j.pbb.2005.04.016 article EN Pharmacology Biochemistry and Behavior 2005-06-21

Organ and tissue dysfunction represents a clinically significant condition. By integrating cell biology with materials science, engineering enables the reconstruction restoration of damaged tissues or organs, offering noninvasive repair approach. In our study, we replicated cellular growth environment by utilizing human umbilical cord-derived decellularized extracellular matrix (dECM) as modifying agent for polyethylene terephthalate (PET) polymeric fiber scaffold. This allowed us to create...

10.3390/polym16131794 article EN Polymers 2024-06-25

Objective: MHC class II molecules play central roles in immune recognition and rejection. As statins have been shown to inhibit the production of these molecules, we analyzed possible immunosuppressive effect pravastatin, using our rat model orthotopic lung transplantation. Methods: Single transplantation was performed a Fischer 344-to-Wistar Kyoto strain combination. One group received pravastatin i.p. after transplantation, controls NaCl. Statin serum levels were by high performance liquid...

10.1016/j.ejcts.2006.03.072 article EN European Journal of Cardio-Thoracic Surgery 2006-07-22

Acute and chronic liver failure are clinically significant conditions, the artificial support system (ALSS) is emerging as a novel effective approach for clinical management of failure. Within this framework, scaffold materials occupy pivotal position integral components bioreactor. Elevating performance capabilities these scaffolds not only augments therapeutic efficacy but also lays groundwork refining selecting large-scale hepatocyte culture models. In study, we introduced material...

10.3390/app14114537 article EN cc-by Applied Sciences 2024-05-25

It has been reported that serum soluble E-selectin (sE-selectin) may be increased in some inflammatory liver diseases. The purpose of our study was to investigate changes sE-selectin, T lymphocyte subsets, natural killer (NK) cells, and HBV load patients with chronic hepatitis B (CHB), analyze the relationship between them, discuss their significances.Fifty-four fourteen controls were studied. Serum NK virus (HBV) detected by enzyme-linked immunosorbent assay (ELISA), flow cytometry (FCM),...

10.1016/j.hepres.2006.03.006 article EN Hepatology Research 2006-05-05
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