A5010426536- Pelvic and Acetabular Injuries
- Abdominal Trauma and Injuries
- Thyroid Cancer Diagnosis and Treatment
- Trauma and Emergency Care Studies
- Mesenchymal stem cell research
- Thyroid and Parathyroid Surgery
- Injury Epidemiology and Prevention
- Pregnancy-related medical research
- Appendicitis Diagnosis and Management
- Urological Disorders and Treatments
- Head and Neck Anomalies
- Nosocomial Infections in ICU
- Cardiac, Anesthesia and Surgical Outcomes
- Cancer-related molecular mechanisms research
- Radiomics and Machine Learning in Medical Imaging
- Cancer, Hypoxia, and Metabolism
- Pancreatic and Hepatic Oncology Research
- Sepsis Diagnosis and Treatment
- Adrenal and Paraganglionic Tumors
- Pneumonia and Respiratory Infections
- Abdominal Surgery and Complications
- Neuroendocrine Tumor Research Advances
- Infectious Diseases and Tuberculosis
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Tissue Engineering and Regenerative Medicine
Yonsei University
2015-2024
Wonju Severance Christian Hospital
2009-2023
Chungbuk National University
2015
Korea Research Institute of Bioscience and Biotechnology
1998-2009
Mesenchymal stem cells (MSCs) are multipotent and give rise to distinctly differentiated from all three germ layers. Neuronal differentiation of MSC has great potential for cellular therapy. We examined whether the cluster mechanically made, not neurosphere, could be into neuron-like by growth factors, such as epidermal factor (EGF), hepatocyte (HGF), vascular endothelial (VEGF).BMSCs grown confluent were separated with cell scrapers masses cultured form BMSCs. As described here BMSCs EGF,...
The mortality rate of patients with hemodynamic instability due to severe pelvic fracture is reported be 40-60% despite a multidisciplinary treatment approach. Angioembolization and external fixation the pelvis are main procedures used control bleeding in these patients. Several studies have shown that preperitoneal packing (PPP) effective for hemorrhage control, being small observational nature. purpose this study was describe Korean trauma center's early experience PPP unstable fractures...
There is an increasing incidence of mortality among trauma patients; therefore, it important to analyze the epidemiology in order prevent death. The authors reviewed retrospectively at a regional emergency center Korea and evaluated main factors that led trauma-related deaths.A total 17007 patients were registered registry Wonju Severance Christian Hospital from January 2010 December 2012.The mean age was 35.2 years old. most frequent mechanism blunt injury (90.8%), as well slip-and-fall...
This study assessed the results of robotic thyroidectomy by fellowship-trained surgeons in their initial independent practice, and whether standard fellowship training for surgery shortens learning curve.This prospective cohort evaluated outcomes 125 patients who underwent using gasless transaxillary single-incision technique 2 recently graduated surgeons. Learning curves were analyzed operation time, with proficiency defined as point at which slope time curve became less steep.Of patients,...
Introduction Despite the use of a multidisciplinary treatment approach, mortality rate hemodynamic instability due to severe pelvic fracture remains 40–60%. Several recent studies have shown that preperitoneal packing (PPP) was useful for achieving hemostasis in these patients acute phase. However, few examined postoperative complications. The purpose present study evaluate clinical outcomes and wound infections PPP patients. Materials methods We retrospectively reviewed medical charts 62...
Background: Among patients with trauma, those self‐harm exhibit different characteristics than who experience general accidents. Unstable vital signs following a severe injury often limit accurate imaging and assessment during initial treatment, rendering decision‐making challenging for definitive care. Identifying correlations between damage area severity can improve predictions treatment decisions. We identify differences in of trauma experienced accidents attempted suicide. Methods: This...
Pu'er tea is a fermented drink made from the leaves of plant, Camellia sinensis. Two novel bacteria, designated strains b09i-3T and b13i-1, were isolated during process fermentation this tea. These isolates Gram-positive, endospore-forming, motile rods that grew at 25–42 °C pH 5.5–10.4. The DNA G+C content was 56.6–58.4 mol%, predominant isoprenoid quinone MK-7 cellular fatty acid anteiso-C15 : 0 (49.0–50 % total). Phylogenetic analysis based on 16S rRNA gene sequences showed b13i-1 shared...
Current management for patients with differentiated thyroid cancer includes near total thyroidectomy and radioactive iodine therapy followed by administration of supraphysiological doses levothyroxine (L-T4). Although hyperthyroidism is a well known risk factor osteoporosis, the effects L-T4 treatment on bone mineral density (BMD) in do not appear to be as significant endogenous hyperthyroidism. In this study, we evaluated impact long-term suppressive BMD turn over markers Korean female...
Two cases of hematological malignancies were reported in an industrial radiography company over a year, which reasonably suspected being consequences prolonged exposure to ionizing radiation because the higher incidence than expected general population. We analyzed chromosomal aberrations peripheral blood lymphocytes from other workers who had been working under similar circumstances as patients company. Among subjects tested, 10 belonged highest band followed up periodically for 1.5 years...
Interferon (IFN)-β and/or tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) secreted by adipose tissue-derived mesenchymal stem cells (ASCs) have been proposed as key mechanistic factors in anti-cancer efficacy lung cancer and breast cells, where they act through paracrine signaling.We hypothesized that IFN-β TRAIL produced ASCs suppress proliferation of hepatocellular carcinoma (HCCs).The present study evaluated the effects on HCCs vitro.We found indirect co-culture with...
An actinomycete strain, 'Nocardia flavorosea' JCM 3332, was found to have properties consistent with its classification in the genus Nocardia. almost complete gene sequence of 16S rDNA strain determined following cloning and sequencing amplified gene. The aligned those available for nocardiae phylogenetic trees were inferred using four tree-making algorithms. organisms consistently formed a distinct clade type Nocardia carnea. However, DNA relatedness experiments showed that N. carnea DSM...
Objective This paper aims to describe the medical service of two polyclinics PyeongChang Winter Olympic Games and analyse injury illness athletes who visited during oilympic period in order provide some insight with respect future construction operation mass gathering events such as Games. Methods The Village was located near Stadium for snow sports Gangneung ice venues athletes. During Games, were consisted emergency outpatient clinics. We retrospectively analysed electronic record data...
The article investigates turbulent flow characteristics and heat transfer enhancement on periodically arranged semicircular ribs fitted in a rectangular channel. channel was fabricated as the aspect ratio of AR 5, rib height to hydraulic diameter 0.07, set e/H 0.117 for various pitch ratios between 8 14. In order predict realistic phenomena near wall, shear stress transport k-ω turbulence v2-f models were chosen. results numerical analysis show characteristics, enhancement, effect friction...
The main issue with the current ultrasonography (US) guidelines is overestimation of malignant and indeterminate nodules as they do not aid in making decisions to treat patients. To overcome this, new US for thyroid that have been shown be better correlated cytologic results proposed. We also suggested specific indications US-guided fine needle aspiration (FNA) using guidelines.Clinical pathologic data from 925 patients 1,419 were retrospectively collected. All subjects underwent US- FNA at...
We evaluated the effectiveness of kaolin-impregnated hemostatic gauze use in preperitoneal pelvic packing (PPP) for patients with hemodynamic instability due to severe fractures.Between May 2014 and October 2018, 53 75 who underwent PPP induced by fracture were enrolled. Their medical records prospectively collected retrospectively analyzed. QuikClot combat (hydrophilic impregnated kaolin) general surgical tape used 21 patients, while was remaining 32 patients.As there differences...
Delta neutrophil index (DNI) can be used as a biomarker for infection to predict patient outcomes. We aimed investigate the relationship between DNI and clinical outcomes in trauma patients who underwent abdominal surgery.We retrospectively analyzed injured emergent surgery regional center of Wonju Severance Christian Hospital March 2016 May 2018. Patient characteristics, operation type, preoperative postoperative laboratory findings, were evaluated. Logistic regression analysis was...