A5034630387- Lung Cancer Diagnosis and Treatment
- Renal and Vascular Pathologies
- Medical Imaging and Pathology Studies
- Infectious Diseases and Tuberculosis
- Epilepsy research and treatment
- Renal cell carcinoma treatment
- Medical Imaging Techniques and Applications
- Neuroscience and Neuropharmacology Research
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Dementia and Cognitive Impairment Research
- Hematological disorders and diagnostics
- Neurological disorders and treatments
- Occupational and environmental lung diseases
- Cardiovascular Effects of Exercise
- Aortic Disease and Treatment Approaches
- Drug-Induced Adverse Reactions
- Atomic and Subatomic Physics Research
- Cerebrovascular and genetic disorders
- Spinal Hematomas and Complications
- Dysphagia Assessment and Management
- Pneumocystis jirovecii pneumonia detection and treatment
- Parkinson's Disease Mechanisms and Treatments
- Genetic Neurodegenerative Diseases
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Palliative Care and End-of-Life Issues
Johannes Gutenberg University Mainz
1996-2017
University Medical Center of the Johannes Gutenberg University Mainz
2011-2015
Klinik und Poliklinik für Nuklearmedizin
2012
Asklepios Klinik Weißenfels
2012
Klinikum Darmstadt
2002-2009
Goethe University Frankfurt
1997
Philipps University of Marburg
1993-1996
University of Tübingen
1992-1994
Universitätsklinikum Tübingen
1992
The use of technical aids to confirm brain death is a controversial matter. Angiography with the intra-arterial administration contrast medium international gold standard, but it not allowed in Germany except cases where provides potential mode treatment. currently approved tests are recordings somatosensory evoked potentials (SSEP), perfusion scintigraphy, transcranial Doppler ultrasonography (TCD), and electroencephalography (EEG). CT angiography (CTA), promising new alternative, being...
<b><i>Background:</i></b> The central nervous system manifestations in Fabry disease (FD) include progressive white matter lesions (WMLs) and stroke. Due to microvascular involvement, men women with FD over 35 years of age develop WMLs. Moreover, the prevalence stroke has been estimated be 12 times higher compared general population. Enzyme replacement therapy (ERT) is available shown beneficial effects on renal, cardiac, peripheral nerve function FD, but ERT effect...
Objective Dopamine is an endogenous neuromodulator in cortical circuits and the basal ganglia. In animal models of temporal lobe epilepsy (TLE), seizure threshold modulated to some extent by dopamine, with D1-receptors having a pro- D2-receptors anticonvulsant effect. We aimed extend our previously reported results on decreased D2/D3 receptor binding lateral epileptogenic correlate them demographic variables gain more comprehensive understanding underlying involvement dopaminergic system...
We constructed and evaluated reference brain FDG-PET databases for usage by three software programs (Computer-aided diagnosis dementia (CAD4D), Statistical Parametric Mapping (SPM) NEUROSTAT), which allow a user-independent detection of dementia-related hypometabolism in patients' FDG-PET.Thirty-seven healthy volunteers were scanned order to construct FDG databases, reflect the normal, age-dependent glucose consumption human brain, using either software. Databases compared each other assess...
Mindfulness denotes a state of consciousness characterized by receptive attention to and awareness present events experiences. As personality trait, it constitutes the ability become aware mental activities such as sensations, images, feelings, thoughts, disengage from judgment, conditioned emotions, their cognitive processing or automatic inhibition. Default brain activity reflects stream sense self at rest. Analysis rest in persons with mindfulness propensity may help elucidate...
Ziel: Bei beatmeten Patienten ist vielerorts der tägliche Röntgenthorax (RT) Bestandteil diagnostischen Routine. Ziele Studie sind unter anderem die Bestimmung von a) Häufigkeit klinisch relevanter Befunde bei Routine-RT chirurgischer Beatmungspatienten, b) Vergleich Erwartungen an den RT Anforderung mit klinischen Relevanz des nach Kenntnis Befundes, c) Indikationen und zusätzlich zur Routine angefertigter RT. Methoden: Prospektive Untersuchung 40 741 Standardisierte Röntgenbefundung....
Evaluation by means of spiral CT as to whether or not a thrombus in proximal deep vein the leg is floating adherent vessel wall.Local application contrast agent into an ipsilateral dorsal foot and were used examine 16 consecutive cases with venous thrombosis proven at conventional venography; addition, colour Doppler flow imaging was performed.At venography, 8/16 thrombi appeared be remaining wall. Spiral-CT showed 15/16 wall; correlated findings venography. At 3/16 considered floating, one...
Drug Prescribing for Patients with Chronic Kidney Disease in General Practice: a Cross-Sectional Study
With the aim to detect Alzheimer's disease (AD) at a pre-dementia stage, new guidelines have been proposed. Imaging findings and CSF biomarkers were suggested as obligatory supportive features, in addition clinical core symptom episodic memory impairment. To test intrinsic consistency of guidelines, we applied them naturalistic non-demented clinic cohort by using different same individuals. We retrospectively studied 70 consecutive patients (global Clinical Dementia Rating 0.5) who underwent...
Einleitung: Die Kernspintomografie gehört zu den wichtigen Instrumenten in der bildgebenden Diagnostik neurologischer Erkrankungen. So werden zum Beispiel bei sporadischen Form Creutzfeld-Jakob-Erkrankung (CJD) häufig bilaterale Hyperintensitäten Basalganglien sowie des Kortex beschrieben. Bei neuen Variante findet sich oft das sogenannte „pulvinar sign“, eine Hyperintensität posterioren Thalamus. Auch anderen Erkrankungen sind ähnliche Veränderungen beschrieben worden. Besonders wichtig...
Dopamine is an endogenous neuromodulator in cortical circuits and basal ganglia. In animal models, it known to affect seizure threshold might have a neuroprotective role temporal lobe epilepsy (TLE).1 models of TLE activation D1- has pro- D2-receptors (D2R) anticonvulsant effect.
The aim of this prospective study was to compare conventional and high resolution CT for demonstrating pulmonary complications. 23 patients treated by bone marrow transplantation were included in the between December 1990 August 1991. These examined radiologically at regular intervals following transplants. In 9 lung changes detected CT: there pneumonic infiltrates, including one CMV pneumonia, two cases mild parenchymal fibrosis, extensive fibrosis miliary tuberculosis. advantages...
Ziele: Die Studie untersucht den Zuwachs an positiven Biopsiebefunden bei Malignomverdacht, wenn mehr als 1 aber maximal 5 Proben entnommen werden. Bringen Gewebeproben einen diagnostischen Gewinn? Methode: Indikation der in dieser eingeschlossenen Biopsien ist die Frage nach Malignität und Histologie Verdacht auf Erstmalignom oder einer Filia versus Zweittumor. Ausgewertet sind prospektiv erfassten Daten CT-gesteuerten Jahre 1998 bis 2001. Durch Schneidbiopsie Koaxialtechnik 175...